Pseudoatrophoderma Colli Medication

Author: Anna Choczaj-Kukula, MD, PhD; Chief Editor: Dirk M Elston, MD more...

Updated: Jan 25, 2012

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Medication Summary
Keratolytics
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References

Medication Summary

The goals of pharmacotherapy are to reduce morbidity and to prevent complications.

Class Summary

These agents are used for symptomatic relief of dry scaling skin and for exfoliation.

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Ammonium lactate 12% (Lac-Hydrin, AmLactin)

Alpha-hydroxy acid; normal constituent of tissues and blood. Believed to act as humectant when applied to the skin. This may influence hydration of the stratum corneum. In addition, when applied to the skin, may act to decrease corneocyte cohesion. The mechanisms by which this is accomplished are not yet known. Relieves itching and aids healing of skin in mild eczemas and dermatoses, itching skin, minor wounds, and minor skin irritations. Found in a variety of topical emollient lotions. Ammonium lactate 5% lotion is available over the counter, and lactic acid 12% cream and lotion are available by prescription.

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Contributor Information and Disclosures

Author

Anna Choczaj-Kukula, MD, PhD Locum Consultant Dermatologist, Barnet and Chase Farm NHS Trust; Honorary Clinical Research Fellow, Royal Free Hospital, UK

Anna Choczaj-Kukula, MD, PhD is a member of the following medical societies: American Academy of Dermatology, British Association of Dermatologists, European Academy of Dermatology and Venereology, and Royal Society of Medicine

Disclosure: Johnson & Johnson Salary Management position

Coauthor(s)

Camila K Janniger, MD Clinical Professor of Dermatology, Clinical Associate Professor of Pediatrics, Chief of Pediatric Dermatology, University of Medicine and Dentistry of New Jersey-New Jersey Medical School

Camila K Janniger, MD is a member of the following medical societies: American Academy of Dermatology

Disclosure: Nothing to disclose.

Chief Editor

Dirk M Elston, MD Director, Ackerman Academy of Dermatopathology, New York

Dirk M Elston, MD is a member of the following medical societies: American Academy of Dermatology

Disclosure: Nothing to disclose.

Additional Contributors

David F Butler, MD Professor of Dermatology, Texas A&M University College of Medicine; Chair, Department of Dermatology, Director, Dermatology Residency Training Program, Scott and White Clinic

Disclosure: Nothing to disclose.

Glen H Crawford, MD Assistant Clinical Professor, Department of Dermatology, University of Pennsylvania School of Medicine; Chief, Division of Dermatology, The Pennsylvania Hospital

Disclosure: Nothing to disclose.

Robert A Schwartz, MD, MPH Professor and Head, Dermatology, Professor of Pathology, Pediatrics, Medicine, and Preventive Medicine and Community Health, UMDNJ-New Jersey Medical School

Disclosure: Nothing to disclose.

Albert C Yan, MD Section Chief, Associate Professor, Department of Pediatrics, Section of Dermatology, Children's Hospital of Philadelphia and University of Pennsylvania

Disclosure: Nothing to disclose.

References

Becker SW, Muir KB. Pseudo-atrophoderma colli: A hitherto undescribed condition. Arch Dermatol Syphilol. 1934;29:53-6.
Ayres S Jr, Ayres S 3rd. Pseudoatrophoderma colli. Arch Dermatol. 1955;71:763-4.
Obermayer ME, Becker SW. Pseudoatrophoderma colli. Arch Dermatol. 1955;72:281-2.
Palomeque FE, Hairston MA Jr. Confluent and reticulated papillomatosis of Gougerot and Carteaud. Arch Dermatol. Jul 1965;92(1):49-51. [Medline].
Frost K, Epstein E. Pseudoatrophoderma colli in sisters. Arch Dermatol Syphilol. 1939;40:755-61.
Kauh YC, Knepp ME, Luscombe HA. Pseudoatrophoderma colli. A familial case. Arch Dermatol. Oct 1980;116(10):1181-2. [Medline].
Kanan MW, Kandil E. Pseudoatrophoderma colli in a male. Br J Dermatol. Jan 1969;81(1):65-8. [Medline].
Kesten BM, James HD. Pseudoatrophoderma colli, acanthosis nigricans, and confluent and reticular papillomatosis. AMA Arch Derm. Apr 1957;75(4):525-42. [Medline].

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Pseudoatrophoderma Colli Medication

Medication Summary

Keratolytics

Class Summary

Ammonium lactate 12% (Lac-Hydrin, AmLactin)