Colloid Milium Differential Diagnoses

  • Author: Susan Cooper, MB, ChB, MD, MRCGP, FRCP; Chief Editor: Dirk M Elston, MD   more...
 
Updated: Aug 2, 2011
 
 

Differential Diagnoses

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Contributor Information and Disclosures
Author

Susan Cooper, MB, ChB, MD, MRCGP, FRCP  Consultant Dermatologist and Honorary Senior Clinical Lecturer, Department of Dermatology, Churchill Hospital, UK

Susan Cooper, MB, ChB, MD, MRCGP, FRCP is a member of the following medical societies: Royal College of Physicians

Disclosure: Nothing to disclose.

Coauthor(s)

Elizabeth Soilleux, PhD, MRCPath  Consultant Pathologist and Honorary Senior Clinical Lecturer, Department of Cellular Pathology, John Radcliffe Hospital, UK

Disclosure: Nothing to disclose.

Specialty Editor Board

Marjan Garmyn, MD, PhD  Professor, Faculty of Medicine, Katholieke Universiteit Leuven, Belgium; Chair and Adjunct Head, Department of Dermatology, University of Leuven, Belgium

Disclosure: Nothing to disclose.

David F Butler, MD  Professor of Dermatology, Texas A&M University College of Medicine; Chair, Department of Dermatology, Director, Dermatology Residency Training Program, Scott and White Clinic, Northside Clinic

David F Butler, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American Medical Association, American Society for Dermatologic Surgery, American Society for MOHS Surgery, Association of Military Dermatologists, and Phi Beta Kappa

Disclosure: Nothing to disclose.

Edward F Chan, MD  Clinical Assistant Professor, Department of Dermatology, University of Pennsylvania School of Medicine

Edward F Chan, MD is a member of the following medical societies: American Academy of Dermatology, American Society of Dermatopathology, and Society for Investigative Dermatology

Disclosure: Nothing to disclose.

Catherine M Quirk, MD  Clinical Assistant Professor, Department of Dermatology, University of Pennsylvania

Catherine M Quirk, MD is a member of the following medical societies: Alpha Omega Alpha and American Academy of Dermatology

Disclosure: Nothing to disclose.

Chief Editor

Dirk M Elston, MD  Director, Ackerman Academy of Dermatopathology, New York

Dirk M Elston, MD is a member of the following medical societies: American Academy of Dermatology

Disclosure: Nothing to disclose.

Acknowledgments

The authors and editors of Medscape Reference gratefully acknowledge the contributions of previous coauthor, Ravi Ratnavel, MD, to the development and writing of this article.

References

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  11. Innocenzi D, Barduagni F, Cerio R, Wolter M. UV-induced colloid milium. Clin Exp Dermatol. Jul 1993;18(4):347-50. [Medline].

  12. Percival GH, Duthie DA. Notes on a case of colloid pseudomilium. Br J Dermatol Syph. Dec 1948;60(12):399-404. [Medline].

  13. Martorell-Calatayud A, Balmer N, Sanmartin O, Botella-Estrada R, Requena C, Guillen-Barona C. Familial juvenile colloid milium: report of a well documented case. J Am Acad Dermatol. Jan 2011;64(1):203-6. [Medline].

  14. Holzberger PC. Concerning adult colloid milium. Arch Dermatol. Nov 1960;82:711-6. [Medline].

  15. Muscardin LM, Bellocci M, Balus L. Papuloverrucous colloid milium: an occupational variant. Br J Dermatol. Oct 2000;143(4):884-7. [Medline].

  16. Findlay GH, Morrison JG, Simson IW. Exogenous ochronosis and pigmented colloid milium from hydroquinone bleaching creams. Br J Dermatol. Dec 1975;93(6):613-22. [Medline].

  17. Lever WG. Colloid milium and nodular colloid degeneration. In: Lever's Histopathology of the Skin. 8th ed. Philadelphia, Pa: WB Saunders; 1997:373-5.

  18. Lai KW, Lambert E, Coleman S, Scott G, Mercurio MG. Nodular amyloidosis: differentiation from colloid milium by electron microscopy. Am J Dermatopathol. Jul 2009;31(5):472-4. [Medline].

  19. Field LM. Re: the long pulsed Er:YAG laser and intravenous sedation versus dermabrasion (or laser) utilizing tumescent anesthesia for colloid milium. Dermatol Surg. Aug 2002;28(8):780. [Medline].

  20. Ammirati CT, Giancola JM, Hruza GJ. Adult-onset facial colloid milium successfully treated with the long-pulsed Er:YAG laser. Dermatol Surg. Mar 2002;28(3):215-9. [Medline].

 
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Hematoxylin and eosin–stained section of skin (X40) showing a central focus of amorphous, eosinophilic, homogenous colloid with surrounding fissuring.
Elastic van Gieson stain of the same area showing strong (black) staining of the colloid for elastin.
 
 
 
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