Colloid Milium Treatment & Management
- Author: Susan Cooper, MB, ChB, MD, MRCGP, FRCP; Chief Editor: Dirk M Elston, MD more...
Medical Care
For colloid milium, no treatment is available that is entirely satisfactory.
Surgical Care
Dermabrasion,[19]cryotherapy, and diathermy have been tried with limited success. Advice about sunscreen use may also be helpful. Systemic ascorbic acid and exfoliating agents have also been tried with variable results. The Er:YAG laser may be more successful for colloid milium than dermabrasion.[20]
Patterson JW, Wilkin JK, Schatzki PF. Nodular colloid degeneration: distinctive histochemical and ultrastructural features. Cutis. Oct 1985;36(4):355-8. [Medline].
Oskay T, Erdem C, Anadolu R, Peksan Y, Ozsoy N, Gul N. Juvenile colloid milium associated with conjunctival and gingival involvement. J Am Acad Dermatol. Dec 2003;49(6):1185-8. [Medline].
Handfield-Jones SE, Atherton DJ, Black MM, Hashimoto K, McKee PH. Juvenile colloid milium: clinical, histological and ultrastructural features. J Cutan Pathol. Oct 1992;19(5):434-8. [Medline].
Gonul M, Cakmak SK, Kilic A, Gul U, Heper AO. Pigmented coalescing papules on the dorsa of the hands: pigmented colloid milium associated with exogenous ochronosis. J Dermatol. Apr 2006;33(4):287-90. [Medline].
Kobayashi H, Hashimoto K. Colloid and elastic fibre: ultrastructural study on the histogenesis of colloid milium. J Cutan Pathol. Apr 1983;10(2):111-22. [Medline].
Hashimoto K, Miller F, Bereston ES. Colloid milium. Histochemical and electron microscopic studies. Arch Dermatol. May 1972;105(5):684-94. [Medline].
Muzaffar W, Dar NR, Malik AM. Colloid milium of the upper eyelid margins: a rare presentation. Ophthalmology. Oct 2002;109(10):1944-6. [Medline].
Chowdhury MM, Blackford S, Williams S. Juvenile colloid milium associated with ligneous conjunctivitis: report of a case and review of the literature. Clin Exp Dermatol. Mar 2000;25(2):138-40. [Medline].
Ojha J, Bhattacharyya I, Islam NM, Wong F, Cohen DM. Colloid milium of the oral cavity: a rare presentation. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. Apr 2008;105(4):e34-8. [Medline].
Lewis AT, Le EH, Quan LT, Krishnan B, Schulmeier J, Hsu S. Unilateral colloid milium of the arm. J Am Acad Dermatol. Feb 2002;46(2 Suppl Case Reports):S5-7. [Medline].
Innocenzi D, Barduagni F, Cerio R, Wolter M. UV-induced colloid milium. Clin Exp Dermatol. Jul 1993;18(4):347-50. [Medline].
Percival GH, Duthie DA. Notes on a case of colloid pseudomilium. Br J Dermatol Syph. Dec 1948;60(12):399-404. [Medline].
Martorell-Calatayud A, Balmer N, Sanmartin O, Botella-Estrada R, Requena C, Guillen-Barona C. Familial juvenile colloid milium: report of a well documented case. J Am Acad Dermatol. Jan 2011;64(1):203-6. [Medline].
Holzberger PC. Concerning adult colloid milium. Arch Dermatol. Nov 1960;82:711-6. [Medline].
Muscardin LM, Bellocci M, Balus L. Papuloverrucous colloid milium: an occupational variant. Br J Dermatol. Oct 2000;143(4):884-7. [Medline].
Findlay GH, Morrison JG, Simson IW. Exogenous ochronosis and pigmented colloid milium from hydroquinone bleaching creams. Br J Dermatol. Dec 1975;93(6):613-22. [Medline].
Lever WG. Colloid milium and nodular colloid degeneration. In: Lever's Histopathology of the Skin. 8th ed. Philadelphia, Pa: WB Saunders; 1997:373-5.
Lai KW, Lambert E, Coleman S, Scott G, Mercurio MG. Nodular amyloidosis: differentiation from colloid milium by electron microscopy. Am J Dermatopathol. Jul 2009;31(5):472-4. [Medline].
Field LM. Re: the long pulsed Er:YAG laser and intravenous sedation versus dermabrasion (or laser) utilizing tumescent anesthesia for colloid milium. Dermatol Surg. Aug 2002;28(8):780. [Medline].
Ammirati CT, Giancola JM, Hruza GJ. Adult-onset facial colloid milium successfully treated with the long-pulsed Er:YAG laser. Dermatol Surg. Mar 2002;28(3):215-9. [Medline].

