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Favre-Racouchot Syndrome (Nodular Elastosis With Cysts and Comedones) Treatment & Management

  • Author: Robert P Feinstein, MD; Chief Editor: Dirk M Elston, MD  more...
Updated: Sep 08, 2015

Medical Care

Sun protection may be of benefit in preventing progression. Advise the patient to avoid sun exposure, particularly between 10:00 am and 2:00 pm. Select sunscreen to provide good protection throughout the UV-A and UV-B range. Sunscreens containing micropulverized titanium dioxide or Parsol 1789 provide the best protection throughout the UV-A range. Smoking cessation also is critical. Application of topical retinoids including tretinoin,[15] adapalene, or tazarotene in various bases will loosen the comedones and assist in the extraction of individual comedones.


Surgical Care

Comedo extraction is effective. However, these comedones are more difficult to extract than are those seen in acne vulgaris. The concomitant use of topical retinoids assists in the extraction process.[16]

Dermabrasion of the affected area has been reported to produce variable cosmetic results.[17]

The comedones can be removed via careful curettage with good cosmetic results.[18]

Chemical peels, laser peels, and staged excision of the involved area have been reported, but the cosmetic result is highly variable.

Treatment with carbon dioxide laser has been reported. Mavilia et al evaluated 50 patients with a superpulsed carbon dioxide laser in an attempt to vaporize epidermis.[19] They then extracted both cystic and comedonal material via soft pressure with a pair of forceps. The laser treatment was performed without topical or intralesional anesthetics, as no pain was reported using the laser parameters they described. The technique proved to be safe and effective in all of the patients treated, assuring an excellent cosmetic result. Rai et al, using a similar approach, confirmed these findings.[20]

Contributor Information and Disclosures

Robert P Feinstein, MD Associate Clinical Professor, Department of Dermatology, Columbia University College of Physicians and Surgeons

Robert P Feinstein, MD is a member of the following medical societies: American Academy of Dermatology, American Medical Association, Noah Worcester Dermatological Society, Phi Beta Kappa

Disclosure: Nothing to disclose.

Specialty Editor Board

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

Edward F Chan, MD Clinical Assistant Professor, Department of Dermatology, University of Pennsylvania School of Medicine

Edward F Chan, MD is a member of the following medical societies: American Academy of Dermatology, American Society of Dermatopathology, Society for Investigative Dermatology

Disclosure: Nothing to disclose.

Chief Editor

Dirk M Elston, MD Professor and Chairman, Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina College of Medicine

Dirk M Elston, MD is a member of the following medical societies: American Academy of Dermatology

Disclosure: Nothing to disclose.

Additional Contributors

Andrea Leigh Zaenglein, MD Professor of Dermatology and Pediatrics, Department of Dermatology, Hershey Medical Center, Pennsylvania State University College of Medicine

Andrea Leigh Zaenglein, MD is a member of the following medical societies: American Academy of Dermatology, Society for Pediatric Dermatology

Disclosure: Received consulting fee from Galderma for consulting; Received consulting fee from Valeant for consulting; Received consulting fee from Promius for consulting; Received consulting fee from Anacor for consulting; Received grant/research funds from Stiefel for investigator; Received grant/research funds from Astellas for investigator; Received grant/research funds from Ranbaxy for other; Received consulting fee from Ranbaxy for consulting.

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