Polymorphous Light Eruption Differential Diagnoses
- Author: Noah S Scheinfeld, MD, JD, FAAD; Chief Editor: Dirk M Elston, MD more...
Guarrera M, Cardo P, Rebora AE, Schena D, Calzavara-Pinton P, Venturini M, et al. Polymorphous light eruption and benign summer light eruption in Italy. Photodermatol Photoimmunol Photomed. Feb 2011;1:35-9. [Medline].
Richards HL, Ling TC, Evangelou G, et al. Psychologic distress in polymorphous light eruption and its relationship to patients' beliefs about their condition. J Am Acad Dermatol. Mar 2007;56(3):426-31. [Medline].
Metelitsa AI, Lauzon GJ. Tobacco and the skin. Clin Dermatol. Jul-Aug 2010;4:384-90. [Medline].
Norris PG, Barker JN, Allen MH, et al. Adhesion molecule expression in polymorphic light eruption. J Invest Dermatol. Oct 1992;99(4):504-8. [Medline].
Stephansson E, Ros AM. Expression of intercellular adhesion molecule-1 (ICAM-1) and OKM5 in UVA- and UVB-induced lesions in patients with lupus erythematosus and polymorphous light eruption. Arch Dermatol Res. 1993;285(6):328-33. [Medline].
Aubin F. Why is polymorphous light eruption so common in young women?. Arch Dermatol Res. Oct 2004;296(5):240-1. [Medline].
Schornagel IJ, Sigurdsson V, Nijhuis EH, Bruijnzeel-Koomen CA, Knol EF. Decreased neutrophil skin infiltration after UVB exposure in patients with polymorphous light eruption. J Invest Dermatol. Jul 2004;123(1):202-6. [Medline].
Kolgen W, van Meurs M, Jongsma M, et al. Differential expression of cytokines in UV-B-exposed skin of patients with polymorphous light eruption: correlation with Langerhans cell migration and immunosuppression. Arch Dermatol. Mar 2004;140(3):295-302. [Medline].
Wackernagel A, Back B, Quehenberger F, Cerroni L, Kerl H, Wolf P. Langerhans cell resistance, CD11b+ cell influx, and cytokine mRNA expression in skin after UV exposure in patients with polymorphous light eruption as compared with healthy control subjects. J Invest Dermatol. May 2004;122(5):1342-4. [Medline].
Koulu LM, Laihia JK, Peltoniemi HH, Jansén CT. UV-induced tolerance to a contact allergen is impaired in polymorphic light eruption. J Invest Dermatol. Nov 2010;130(11):2578-82. [Medline].
Kerr HA, Lim HW. Photodermatoses in African Americans: a retrospective analysis of 135 patients over a 7-year period. J Am Acad Dermatol. Oct 2007;57(4):638-43. [Medline].
Benanni B, Bruckner T, Bock M, et al. Low incidence of polymorphous light eruption in renal transplant recipients. Acta Derm Venereol. 2007;87(4):372-4. [Medline].
Hönigsmann H. Polymorphous light eruption. Photodermatol Photoimmunol Photomed. Jun 2008;24(3):155-61. [Medline].
Deng D, Hang Y, Chen H, Li H. Prevalence of photodermatosis in four regions at different altitudes in Yunnan province, China. J Dermatol. Aug 2006;33(8):537-40. [Medline].
Draelos ZK, Hansen RC. Polymorphic light eruption in pediatric patients with American Indian ancestry. Pediatr Dermatol. Nov 1986;3(5):384-9. [Medline].
Naleway AL, Greenlee RT, Melski JW. Characteristics of diagnosed polymorphous light eruption. Photodermatol Photoimmunol Photomed. Aug 2006;22(4):205-7. [Medline].
Lugovic Mihic L, Bulat V, Situm M, Cavka V, Krolo I. Allergic hypersensitivity skin reactions following sun exposure. Coll Antropol. Oct 2008;32 Suppl 2:153-7. [Medline].
Jansen CT. The natural history of polymorphous light eruptions. Arch Dermatol. Feb 1979;115(2):165-9. [Medline].
Majoie IM, van Weelden H, Sybesma IM, Coenraads PJ, Sigurdsson V. Polymorphous light eruption-like skin lesions in welders caused by ultraviolet C light. J Am Acad Dermatol. Jan 2010;62(1):150-1. [Medline].
Kontos AP, Cusack CA, Chaffins M, Lim HW. Polymorphous light eruption in African Americans: pinpoint papular variant. Photodermatol Photoimmunol Photomed. Dec 2002;18(6):303-6. [Medline].
Chiam LY, Chong WS. Pinpoint papular polymorphous light eruption in Asian skin: a variant in darker-skinned individuals. Photodermatol Photoimmunol Photomed. 2009;25:71-4. [Medline].
Gronhagen CM, Gunnarsson I, Svenungsson E, Nyberg F. Cutaneous manifestations and serological findings in 260 patients with systemic lupus erythematosus. Lupus. Sep 2010;19(10):1187-94. [Medline].
Popovic K, Nyberg F, Wahren-Herlenius M, Nyberg F. A serology-based approach combined with clinical examination of 125 Ro/SSA-positive patients to define incidence and prevalence of subacute cutaneous lupus erythematosus. Arthritis Rheum. Jan 2007;56(1):255-64. [Medline].
Schornagel IJ, Guikers KL, Van Weelden H, Brijnzeel-Koomen CA, Sigurdsson V. The polymorphous light eruption-severity assessment score does not reliably predict the results of phototesting. J Eur Acad Dermatol Venereol. Jun 2008;22(6):675-80. [Medline].
Leroy D, Dompmartin A, Verneuil L, Michel M, Faguer K. [Polychromatic phototest sensibility is superior to UVA phototest in polymorphic light eruptions]. Ann Dermatol Venereol. Jun-Jul 2002;129(6-7):860-4. [Medline].
Hadshiew IM, Treder-Conrad C, v Bülow R, et al. Polymorphous light eruption (PLE) and a new potent antioxidant and UVA-protective formulation as prophylaxis. Photodermatol Photoimmunol Photomed. Aug 2004;20(4):200-4. [Medline].
Gruber-Wackernagel A, Bambach I, Legat FJ, et al. Randomized double-blinded placebo-controlled intra-individual trial on topical treatment with a 1,25-dihydroxyvitamin D(3) analogue in polymorphic light eruption. Br J Dermatol. Jul 2011;165(1):152-63. [Medline].
Jeanmougin M, Peyron JL, Thomas P, Beani JC, Guez E, Bachot N. [Polymorphic light eruption: prophylaxis using a topical combination of antioxidants and UVA protection formulations]. Ann Dermatol Venereol. May 2006;133(5 Pt 1):425-8. [Medline].
DeLeo VA, Clark S, Fowler J, Poncet M, Loesche C, Soto P. A new ecamsule-containing SPF 40 sunscreen cream for the prevention of polymorphous light eruption: a double-blind, randomized, controlled study in maximized outdoor conditions. Cutis. Feb 2009;83(2):95-103. [Medline].
Fourtanier A, Moyal D, Seite S. Sunscreens containing the broad-spectrum UVA absorber, Mexoryl SX, prevent the cutaneous detrimental effects of UV exposure: a review of clinical study results. Photodermatol Photoimmunol Photomed. Aug 2008;24(4):164-74. [Medline].
Murphy GM, Logan RA, Lovell CR, Morris RW, Hawk JL, Magnus IA. Prophylactic PUVA and UVB therapy in polymorphic light eruption--a controlled trial. Br J Dermatol. Apr 1987;116(4):531-8. [Medline].
Bilsland D, George SA, Gibbs NK, Aitchison T, Johnson BE, Ferguson J. A comparison of narrow band phototherapy (TL-01) and photochemotherapy (PUVA) in the management of polymorphic light eruption. Br J Dermatol. Dec 1993;129(6):708-12. [Medline].
Barolet D, Boucher A. LED photoprevention: reduced MED response following multiple LED exposures. Lasers Surg Med. Feb 2008;40(2):106-12. [Medline].
Jansen CT. Oral carotenoid treatment in polymorphous light eruption: a cross-over comparison with oxychloroquine and placebo. Photodermatol. Jun 1985;2(3):166-9. [Medline].
Neumann R, Rappold E, Pohl-Markl H. Treatment of polymorphous light eruption with nicotinamide: a pilot study. Br J Dermatol. Jul 1986;115(1):77-80. [Medline].
Ahmed RS, Suke SG, Seth V, Jain A, Bhattacharya SN, Banerjee BD. Impact of oral vitamin E supplementation on oxidative stress & lipid peroxidation in patients with polymorphous light eruption. Indian J Med Res. Jun 2006;123(6):781-7. [Medline].
Norris PG, Hawk JL. Successful treatment of severe polymorphous light eruption with azathioprine. Arch Dermatol. Oct 1989;125(10):1377-9. [Medline].
Boonstra HE, van Weelden H, Toonstra J, van Vloten WA. Polymorphous light eruption: A clinical, photobiologic, and follow-up study of 110 patients. J Am Acad Dermatol. Feb 2000;42(2 Pt 1):199-207. [Medline].
Calzavara Pinton PG, Venturini M, Capezzera R, Zane C, Facchetti F. Photosensitive erythema multiforme and erythema multiforme-like polymorphous light eruption. Photodermatol Photoimmunol Photomed. Jun 2003;19(3):157-9. [Medline].
Dummer R, Ivanova K, Scheidegger EP, Burg G. Clinical and therapeutic aspects of polymorphous light eruption. Dermatology. 2003;207(1):93-5. [Medline].
Epstein JH. Polymorphous light eruption. J Am Acad Dermatol. Oct 1980;3(4):329-43. [Medline].
Epstein JH. Polymorphous light eruption. Photodermatol Photoimmunol Photomed. Jun 1997;13(3):89-90. [Medline].
Fesq H, Ring J, Abeck D. Management of polymorphous light eruption : clinical course, pathogenesis, diagnosis and intervention. Am J Clin Dermatol. 2003;4(6):399-406. [Medline].
Jansen CT. The morphologic features of polymorphous light eruptions. Cutis. Aug 1980;26(2):164-7, 169-70. [Medline].
McFadden N, Larsen TE. Polymorphous light eruption: the properties of a UVA-induced PLME patient group. Photodermatol. Feb 1986;3(1):36-40. [Medline].
Muhlbauer JE, Mihm MC Jr, Harrist TJ. Papular polymorphous light eruption. Fibrin, complement, and immunoglobulin deposition. Arch Dermatol. Jul 1984;120(7):866-8. [Medline].
Schornagel IJ, Knol EF, van Weelden H, Guikers CL, Bruijnzeel-Koomen CA, Sigurdsson V. Diagnostic phototesting in polymorphous light eruption: the optimal number of irradiations. Br J Dermatol. Dec 2005;153(6):1234-6. [Medline].

