Background
Poikiloderma of Civatte refers to erythema associated with a mottled pigmentation seen on the sides of the neck, more commonly in women. Civatte first described the condition in 1923.
Pathophysiology
Poikiloderma of Civatte is a rather common, benign condition affecting the skin. Many consider it to be a reaction pattern of the skin and not a disease. The term poikiloderma refers to the combination of atrophy, telangiectasia, and pigmentary changes (both hypopigmentation and hyperpigmentation). Poikilodermatous lesions may be seen in certain genodermatoses (Rothmund-Thomson syndrome, Bloom syndrome, dyskeratosis congenita), in connective-tissue diseases (dermatomyositis, lupus erythematosus), in parapsoriasis/mycosis fungoides, and in radiodermatitis.
Epidemiology
Frequency
International
The incidence of poikiloderma of Civatte is unknown; many patients may have a mild form of the disease and may not seek medical attention.
Mortality/Morbidity
In most patients, the condition is of purely cosmetic concern. Patients with the mild form do not seek medical advice.
Race
Poikiloderma of Civatte occurs most commonly in fair-skinned individuals.
Sex
Poikiloderma of Civatte occurs more commonly in females than in males.[1]
Age
Most commonly, individuals affected are middle-aged or elderly women; however, the disease has been seen in other age groups.
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