Neurotic Excoriations Treatment & Management
- Author: Noah S Scheinfeld, MD, JD, FAAD; Chief Editor: Dirk M Elston, MD more...
Medical Care
In 2005, Krishnan and Koo[10] reported that the pathology of the opioid neurotransmitter system and the central nervous system is the neurological basis for neurotic excoriations and thus psychiatric medications that can normalize nervous system pathology can abate neurotic excoriations.
In the treatment of neurotic excoriations, studies have shown that the serotonergic effect of selective serotonin reuptake inhibitors (SSRIs) produce an antipruritic effect.[11] The relief of pruritus is unrelated to changes in the patient's mood and happens faster than would be expected for antidepressant effects.
For its sedating and antipsychotic effects, doxepin (10-25 mg PO qhs) is a useful medication in treating neurotic excoriations.
Dereli et al[12] found that gabapentin is a useful treatment for recalcitrant chronic prurigo nodularis.
Surgical Care
Physical barriers such as an Unna sleeve can be an effective treatment for neurotic excoriations.[13]
Consultations
Consult a psychiatrist and a psychologist. Neurotic excoriations can be associated with psychopathology. Social stressors may be well hidden because of shame or a delusional belief system. Suppression, inappropriate channeling, and repression of aggression can be a result of unmet emotional needs. Conflicts can result from past or current situations. Resolving these issues alone can be difficult. Neurotic excoriations can be associated with anxiety disorders, low self-confidence, generalized apprehension, meticulousness, depressive mood, and hypersensitivity to perceived self-negativism. Thus, the intervention of a psychiatrist or other trained mental health care professionals can be useful. Patients can benefit from psychotherapy and other forms of counseling.[14]
Jafferany M, Vander Stoep A, Dumitrescu A, Hornung RL. The knowledge, awareness, and practice patterns of dermatologists toward psychocutaneous disorders: results of a survey study. Int J Dermatol. Jul 2010;49(7):784-9. [Medline].
Brodin MB. Neurotic excoriations. J Am Acad Dermatol. Aug 2010;2:341-2. [Medline].
Jafferany M, Vander Stoep A, Dumitrescu A, Hornung RL. The knowledge, awareness, and practice patterns of dermatologists toward psychocutaneous disorders: results of a survey study. Int J Dermatol. Jul 2010;7:784-9. [Medline].
Shah KN, Fried RG. Factitial dermatoses in children. Curr Opin Pediatr. Aug 2006;18(4):403-9. [Medline].
Andreoli E, Finore ED, Provini A, Paradisi M. [Self-inflicted dermatitis: a case in pediatric age]. Minerva Pediatr. Jun 2008;60(3):355-9. [Medline].
Cyr PR, Dreher GK. Neurotic excoriations. Am Fam Physician. Dec 15 2001;64(12):1981-4. [Medline].
Setyadi HG, Cohen PR, Schulze KE, et al. Trigeminal trophic syndrome. South Med J. Jan 2007;100(1):43-8. [Medline].
Shenefelt PD. Using hypnosis to facilitate resolution of psychogenic excoriations in acne excoriée. Am J Clin Hypn. Jan 2004;46(3):239-45. [Medline].
Koblenzer CS. Neurotic excoriations and dermatitis artefacta. Dermatol Clin. Jul 1996;14(3):447-55. [Medline].
Krishnan A, Koo J. Psyche, opioids, and itch: therapeutic consequences. Dermatol Ther. Jul-Aug 2005;18(4):314-22. [Medline].
Fellner MJ, Majeed MH. Tales of bugs, delusions of parasitosis, and what to do. Clin Dermatol. Jan-Feb 2009;27(1):135-8. [Medline].
Dereli T, Karaca N, Inanir I, Oztürk G. Gabapentin for the treatment of recalcitrant chronic prurigo nodularis. Eur J Dermatol. Jan-Feb 2008;18(1):85-6. [Medline].
Paley K, Prevost N, English JC 3rd. Unna sleeve for neurotic excoriations. Cutis. Mar 2010;85(3):149-52. [Medline].
Fried RG. Nonpharmacologic treatments in psychodermatology. Dermatol Clin. Jan 2002;20(1):177-85. [Medline].
Gupta MA, Gupta AK. Olanzapine may be an effective adjunctive therapy in the management of acne excoriée: a case report. J Cutan Med Surg. Jan-Feb 2001;5(1):25-7. [Medline].
Biondi M, Arcangeli T, Petrucci RM. Paroxetine in a case of psychogenic pruritus and neurotic excoriations. Psychother Psychosom. May-Jun 2000;69(3):165-6. [Medline].
Gupta MA, Gupta AK. Fluoxetine is an effective treatment for neurotic excoriations: case report. Cutis. May 1993;51(5):386-7. [Medline].
Fried R. Psychodermatology. Dialogues in Dermatology. American Academy of Dermatology. Available at http://www.aad.org/Marketplace/Catalog/dialogues.html. Accessed 2003.

