Laboratory Studies
- Potassium hydroxide (KOH) slide preparation and culture for Candida species
- A KOH preparation allows for the rapid visualization of the candidal hyphae.
- Culture often isolates candidal species in these cases and helps to direct proper treatment.
Imaging Studies
- No imaging studies are indicated.
Other Tests
- Rarely, serologic tests for candidal species may be indicated, particularly in unclear cases and for academic interest.
Procedures
- Biopsy from the involved area
- Biopsy is performed in doubtful cases and if antifungal treatment fails to produce a favorable response.
- A biopsy is especially warranted if premalignant or malignant lesions, such as erythroplasia of Queyrat or Bowen disease, are suspected and need to be excluded.
Histologic Findings
The histologic findings are nonspecific and eczematous in nature. Dermis contains lymphoplasmacytic infiltrates. Special stains for fungi, such as the periodic acid-Schiff (PAS) stain, may exhibit fungal elements characteristic of candidal organisms.
See the image below.
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