Roseola Infantum Differential Diagnoses
- Author: Christopher R Gorman, MD; Chief Editor: William D James, MD more...
Also consider the following:
Viral syndromes with fever and exanthem
In patients who are immunocompromised, many differential diagnoses, including viral, bacterial, fungal, and immunologic conditions, exist.
In 2005, Ward suggested testing for human herpesvirus (HHV)–6 and HHV-7 primary infection when serious neurological disease/encephalitis is temporally related to immunization, lest the condition be misdiagnosed as a vaccine reaction.[8, 9]
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Vianna RA, de Oliveira SA, Camacho LA, et al. Role of human herpesvirus 6 infection in young Brazilian children with rash illnesses. Pediatr Infect Dis J. 2008 Jun. 27(6):533-7. [Medline].
Magalhães Ide M, Martins RV, Vianna RO, Moysés N, Afonso LA, Oliveira SA, et al. Detection of human herpesvirus 7 infection in young children presenting with exanthema subitum. Mem Inst Oswaldo Cruz. 2011 May. 106(3):371-3. [Medline].
Ward KN. The natural history and laboratory diagnosis of human herpesviruses-6 and -7 infections in the immunocompetent. J Clin Virol. 2005 Mar. 32(3):183-93. [Medline].
Ward KN, Andrews NJ, Verity CM, Miller E, Ross EM. Human herpesviruses-6 and -7 each cause significant neurological morbidity in Britain and Ireland. Arch Dis Child. 2005 Jun. 90(6):619-23. [Medline].
Stone RC, Micali GA, Schwartz RA. Roseola infantum and its causal human herpesviruses. Int J Dermatol. 2014 Apr. 53(4):397-403. [Medline].
Rapaport D, Engelhard D, Tagger G, Or R, Frenkel N. Antiviral prophylaxis may prevent human herpesvirus-6 reactivation in bone marrow transplant recipients. Transpl Infect Dis. 2002 Mar. 4(1):10-6. [Medline].