Dermatologic Manifestations of Rubella Medication

  • Author: Peter C Lombardo, MD; Chief Editor: Dirk M Elston, MD  more...
Updated: Oct 13, 2015

Medication Summary

No specific medication is available for rubella, except that given for symptomatic relief. High fever and polyarthralgia are rare in children; however, if present, acetaminophen may be used. In adults, in whom fever and polyarthralgia are more common, acetaminophen, aspirin, or other nonsteroidal anti-inflammatory drugs (NSAIDs) are useful.


Analgesics, salicylate

Class Summary

These agents can reduce inflammation and fever.

Aspirin (Anacin, Ascriptin, Bayer Aspirin)


Aspirin treats mild to moderate pain and headache. It inhibits prostaglandin synthesis, which prevents the formation of platelet-aggregating thromboxane A2. Aspirin acts on the heat-regulating center of the hypothalamus and vasodilates peripheral vessels to reduce fever.


Nonsteroidal anti-inflammatory agents

Class Summary

These agents have analgesic and antipyretic activities. Their mechanism of action is not known, but they may inhibit cyclo-oxygenase activity and prostaglandin synthesis. Other mechanisms (eg, inhibition of leukotriene synthesis, lysosomal enzyme release, lipoxygenase activity, neutrophil aggregation, various cell membrane functions) may also exist. Although its effects in the treatment of pain tend to be patient-specific, ibuprofen is usually DOC for initial therapy.

Ibuprofen (Ibuprin, Advil, Motrin)


Ibuprofen is the drug of choice for mild to moderate pain. It inhibits inflammatory reactions and pain by decreasing prostaglandin synthesis. It is one of the few NSAIDs indicated for reduction of fever.

Contributor Information and Disclosures

Peter C Lombardo, MD Clinical Associate Professor, Department of Dermatology, Columbia University College of Physicians and Surgeons; Private Practice, Sutton Place Dermatology, PC

Peter C Lombardo, MD is a member of the following medical societies: American Academy of Dermatology, Dermatologic Society of Greater New York, New York State Society of Dermatology and Dermatological Surgery, American Medical Association, New York Academy of Medicine

Disclosure: Nothing to disclose.

Specialty Editor Board

Richard P Vinson, MD Assistant Clinical Professor, Department of Dermatology, Texas Tech University Health Sciences Center, Paul L Foster School of Medicine; Consulting Staff, Mountain View Dermatology, PA

Richard P Vinson, MD is a member of the following medical societies: American Academy of Dermatology, Texas Medical Association, Association of Military Dermatologists, Texas Dermatological Society

Disclosure: Nothing to disclose.

Van Perry, MD Assistant Professor, Department of Medicine, Division of Dermatology, University of Texas School of Medicine at San Antonio

Van Perry, MD is a member of the following medical societies: American Academy of Dermatology

Disclosure: Nothing to disclose.

Chief Editor

Dirk M Elston, MD Professor and Chairman, Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina College of Medicine

Dirk M Elston, MD is a member of the following medical societies: American Academy of Dermatology

Disclosure: Nothing to disclose.

Additional Contributors

Gregory J Raugi, MD, PhD Professor, Department of Internal Medicine, Division of Dermatology, University of Washington at Seattle School of Medicine; Chief, Dermatology Section, Primary and Specialty Care Service, Veterans Administration Medical Center of Seattle

Gregory J Raugi, MD, PhD is a member of the following medical societies: American Academy of Dermatology

Disclosure: Nothing to disclose.


The authors and editors of Medscape Reference gratefully acknowledge the contributions of previous Chief Editor, William D. James, MD, to the development and writing of this article.

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