Dermatologic Manifestations of Rubella Medication
- Author: Peter C Lombardo, MD; Chief Editor: Dirk M Elston, MD more...
No specific medication is available for rubella, except that given for symptomatic relief. High fever and polyarthralgia are rare in children; however, if present, acetaminophen may be used. In adults, in whom fever and polyarthralgia are more common, acetaminophen, aspirin, or other nonsteroidal anti-inflammatory drugs (NSAIDs) are useful.
These agents can reduce inflammation and fever.
Aspirin treats mild to moderate pain and headache. It inhibits prostaglandin synthesis, which prevents the formation of platelet-aggregating thromboxane A2. Aspirin acts on the heat-regulating center of the hypothalamus and vasodilates peripheral vessels to reduce fever.
Nonsteroidal anti-inflammatory agents
These agents have analgesic and antipyretic activities. Their mechanism of action is not known, but they may inhibit cyclo-oxygenase activity and prostaglandin synthesis. Other mechanisms (eg, inhibition of leukotriene synthesis, lysosomal enzyme release, lipoxygenase activity, neutrophil aggregation, various cell membrane functions) may also exist. Although its effects in the treatment of pain tend to be patient-specific, ibuprofen is usually DOC for initial therapy.
Ibuprofen is the drug of choice for mild to moderate pain. It inhibits inflammatory reactions and pain by decreasing prostaglandin synthesis. It is one of the few NSAIDs indicated for reduction of fever.
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