eMedicine Specialties > Dermatology > Viral Infections

Cutaneous Manifestations of Hepatitis C: Treatment & Medication

Author: Robert A Schwartz, MD, MPH, Professor and Head, Dermatology, Professor of Pathology, Pediatrics, Medicine, and Preventive Medicine and Community Health, UMDNJ-New Jersey Medical School
Coauthor(s): Arthur P Birnkrant, MD, Clinical Instructor, Department of Dermatology, University of Medicine and Dentistry of New Jersey
Contributor Information and Disclosures

Updated: Sep 8, 2009

Treatment

Medical Care

Treatment of patients with extrahepatic dermatologic manifestations of hepatitis C virus (HCV) infection is the same as that of HCV infective state and the customary treatments of the individual conditions. Many, if not all, of the dermatologic manifestations disappear when appropriate HCV treatment or viral clearance occurs. Malignant conditions may even disappear with effective therapy for the underlying chronic hepatitis C infection.

  • Currently, medical treatment of patients with HCV infection consists of interferon and ribavirin therapy.
  • Medical therapy for patients with individual extrahepatic dermatologic manifestations of HCV infection depends on the condition.

Also see the clinical guideline summary from the British Association for Sexual Health and HIV: United Kingdom national guideline on the management of the viral hepatitides A, B, and C 2008.69

Consultations

  • Involving specialists for both treatment and follow-up care often maximizes the care of individuals with extrahepatic cutaneous manifestations of hepatitis C virus (HCV). Monitoring of liver status and liver disease progression is beyond the usual purview of dermatologists and may necessitate consultation with gastroenterologists and hepatic specialists in the care of patients.
  • Cutaneous manifestations, serious vasculitis, lymphomas, hepatomas, and metabolic disorders may require high-level management with a team approach. Individual specialists may be an important resource in the care of patients.

More on Cutaneous Manifestations of Hepatitis C

Overview: Cutaneous Manifestations of Hepatitis C
Differential Diagnoses & Workup: Cutaneous Manifestations of Hepatitis C
Treatment & Medication: Cutaneous Manifestations of Hepatitis C
Follow-up: Cutaneous Manifestations of Hepatitis C
Multimedia: Cutaneous Manifestations of Hepatitis C
References
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References

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Further Reading

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Keywords

hepatitis C virus, hepatitis C virus skin disease, HCV skin disease, lichen planus, acral necrolytic erythema, sialadenitis, chronic hepatitis C, cryoglobulinemia, leukocytoclastic vasculitis, Mooren corneal ulcer, antiphospholipid syndrome, Behcet's disease, Behcet disease, canities, Hyde's prurigo nodularis, Hyde prurigo nodularis, thyroiditis, thrombocytopenia, vitiligo, polyarteritis nodosa, pruritus, urticaria, hepatic failure, thyroid failure, porphyria cutanea tarda, non-Hodgkin lymphoma, verrucous squamous cell carcinoma of the tongue, mucosa-associated lymphoid tumor syndrome, MALT syndrome, hepatoma, lichen planus, erythema dyschromicum perstans, disseminated superficial actinic porokeratosis, hepatocellular cancer, granuloma annulare, symmetric polyarthritis, livido reticularis, arteriovenous hemangiomas, Gougerot-Blum disease, capillaritis of the lower legs, Schamberg's disease, Schamberg disease, progressive pigmented purpura

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Contributor Information and Disclosures

Author

Robert A Schwartz, MD, MPH, Professor and Head, Dermatology, Professor of Pathology, Pediatrics, Medicine, and Preventive Medicine and Community Health, UMDNJ-New Jersey Medical School
Robert A Schwartz, MD, MPH is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American College of Physicians, and Sigma Xi
Disclosure: Nothing to disclose.

Coauthor(s)

Arthur P Birnkrant, MD, Clinical Instructor, Department of Dermatology, University of Medicine and Dentistry of New Jersey
Arthur P Birnkrant, MD is a member of the following medical societies: American Academy of Dermatology and American Society for MOHS Surgery
Disclosure: Nothing to disclose.

Medical Editor

Craig A Elmets, MD, Director of Dermatology, Departments of Dermatology, Pathology, and Environmental Health Sciences; Professor, The Kirklin Clinic, University of Alabama at Birmingham
Craig A Elmets, MD is a member of the following medical societies: American Academy of Dermatology, American Association of Immunologists, American College of Physicians, American Federation for Medical Research, and Society for Investigative Dermatology
Disclosure: Palomar Medical Technologies Stock None; Amgen Consulting fee Review panel membership; Astellas Consulting fee Review panel membership; Massachusetts Medical Society Salary Employment; Abbott Laboratories Grant/research funds Independent contractor

Pharmacy Editor

David F Butler, MD, Professor of Dermatology, Texas A&M University College of Medicine; Chair, Department of Dermatology, Director, Dermatology Residency Training Program, Scott and White Clinic, Northside Clinic
David F Butler, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American Medical Association, American Society for Dermatologic Surgery, American Society for MOHS Surgery, Association of Military Dermatologists, and Phi Beta Kappa
Disclosure: Nothing to disclose.

Managing Editor

Jeffrey P Callen, MD, Professor of Medicine, Chief, Division of Dermatology, University of Louisville School of Medicine
Jeffrey P Callen, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American College of Physicians, and American College of Rheumatology
Disclosure: Amgen Honoraria Consulting; Abbott Honoraria Consulting; Electrical Optical Sciences Honoraria Consulting; Centocor Honoraria Consulting; Medicis Honoraria Consulting; Celgene Honoraria Consulting

CME Editor

Catherine Quirk, MD, Clinical Assistant Professor, Department of Dermatology, Brown University
Catherine Quirk, MD is a member of the following medical societies: Alpha Omega Alpha and American Academy of Dermatology
Disclosure: Nothing to disclose.

Chief Editor

Dirk M Elston, MD, Director, Department of Dermatology, Geisinger Medical Center
Dirk M Elston, MD is a member of the following medical societies: American Academy of Dermatology
Disclosure: Nothing to disclose.

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