Radial Mononeuropathy 

  • Author: Wayne E Anderson, DO; Chief Editor: Nicholas Lorenzo, MD   more...
 
Updated: Jun 11, 2010
 

Background

Radial neuropathies result from injury due to penetrating wounds or fractures of the arm, compression, or ischemia. Most commonly, they present with a wrist drop. The pattern of clinical involvement is dependent on the level of injury.

Radial neuropathies can occur from surgical procedures such as humeral nailing performed to stabilize an acute humeral fracture.[1]

The terms Saturday night palsy and honeymooner's palsy refer to the concept of placing one's arm over another chair, with the resultant pressure causing injury to the radial nerve.

Next

Pathophysiology

An introduction to radial nerve anatomy is essential for understanding the common mechanisms and location of its injury. The radial nerve branches from the posterior cord of the brachial plexus. It receives root innervation from C5-T1 spinal roots. In the upper arm, the radial nerve gives off a branch to the triceps muscle before it wraps around the humerus at the spiral groove. Three sensory branches, which supply the skin over the triceps and posterior forearm, also are given off at this level. Here, its proximity to the humerus makes it susceptible to compression and/or trauma.

After exiting the spiral groove, the radial nerve supplies the brachioradialis muscle before dividing into the posterior interosseous branch and a sensory branch. The posterior interosseous branch is a pure motor nerve that supplies the supinator. It then dives into the supinator through the fascia to supply the muscles of the wrist and finger extension. This fascia is another common site for nerve damage to occur. The sensory branch that arises approximately at the elbow travels down the forearm, becoming superficial at the wrist before it supplies the lateral aspect of the dorsum of the hand.

The Radial Nerve from Gray's Anatomy (published 19The Radial Nerve from Gray's Anatomy (published 1918, public domain, copyright expired).
Previous
Next

Epidemiology

Frequency

United States

Radial neuropathy is the fourth most common mononeuropathy.

Race

No racial preponderance is known.

Sex

No gender predilection has been observed.

Age

Radial neuropathy is reported in all age groups.

Previous
 
 
Contributor Information and Disclosures
Author

Wayne E Anderson, DO  Assistant Professor of Internal Medicine/Neurology, Western University of Health Sciences; Assistant Professor of Family Medicine, Touro University College of Osteopathic Medicine; Consulting Staff in Pain Management, Department of Neurology, California Pacific Medical Center; Consulting Staff in Neurology, Department of Neurology, California Pacific Medical Center

Wayne E Anderson, DO is a member of the following medical societies: American Academy of Neurology, American Medical Association, American Society of Law, Medicine & Ethics, California Medical Association, and San Francisco Medical Society

Disclosure: Cephalon Honoraria Speaking and teaching; Pfizer Honoraria Speaking and teaching; King Honoraria Speaking and teaching; Forest Honoraria Speaking and teaching

Specialty Editor Board

Aashit K Shah, MD  Associate Professor of Neurology, Wayne State University; Program Director, Clinical Neurophysiology Fellowship, Department of Neurology, Detroit Medical Center

Aashit K Shah, MD is a member of the following medical societies: American Academy of Neurology, American Clinical Neurophysiology Society, and American Epilepsy Society

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD  Senior Pharmacy Editor, eMedicine

Disclosure: eMedicine Salary Employment

Neil A Busis, MD  Chief, Division of Neurology, Department of Medicine, Head, Clinical Neurophysiology Laboratory, University of Pittsburgh Medical Center-Shadyside

Neil A Busis, MD is a member of the following medical societies: American Academy of Neurology and American Association of Neuromuscular and Electrodiagnostic Medicine

Disclosure: Nothing to disclose.

Chief Editor

Nicholas Lorenzo, MD  Chief Editor, eMedicine Neurology; Consulting Staff, Neurology Specialists and Consultants

Nicholas Lorenzo, MD is a member of the following medical societies: Alpha Omega Alpha and American Academy of Neurology

Disclosure: Nothing to disclose.

References
  1. Rommens PM, Kuechle R, Bord T, Lewens T, Engelmann R, Blum J. Humeral nailing revisited. Injury. Apr 14 2008;[Medline].

  2. Moore FG. Radial neuropathies in wheelchair users. Am J Phys Med Rehabil. Dec 2009;88(12):1017-9. [Medline].

  3. Furuta T, Okamoto Y, Tohno E, Minami M, Nishiura Y, Ohtomo K. Magnetic resonance microscopy imaging of posterior interosseous nerve palsy. Jpn J Radiol. Jan 2009;27(1):41-4. [Medline].

  4. Jou IM, Wang HN, Wang PH, Yong IS, Su WR. Compression of the radial nerve at the elbow by a ganglion: two case reports. J Med Case Reports. Jun 5 2009;3:7258. [Medline].

  5. Shobha N, Taly AB, Sinha S, Venkatesh T. Radial neuropathy due to occupational lead exposure: Phenotypic and electrophysiological characteristics of five patients. Ann Indian Acad Neurol. Apr 2009;12(2):111-5. [Medline].

  6. Lo YL, Fook-Chong S, Leoh TH, Dan YF, Tan YE, Lee MP. Rapid ultrasonographic diagnosis of radial entrapment neuropathy at the spiral groove. J Neurol Sci. May 10 2008;[Medline].

  7. Liotta G, Granata G, Librante A, Di Pasquale A, Caliandro P, Martinoli C, et al. Atypical double nerve lesion after humeral fracture: diagnosis by ultrasound. Muscle Nerve. Feb 2010;41(2):287-8. [Medline].

  8. Visser LH. High-resolution sonography of the superficial radial nerve with two case reports. Muscle Nerve. Mar 2009;39(3):392-5. [Medline].

  9. Lee FC, Singh H, Nazarian LN, Ratliff JK. High-resolution ultrasonography in the diagnosis and intraoperative management of peripheral nerve lesions. J Neurosurg. Mar 12 2010;[Medline].

  10. Bumbasirevic M, Lesic A, Bumbasirevic V, Cobeljic G, Milosevic I, Atkinson HD. The management of humeral shaft fractures with associated radial nerve palsy: a review of 117 cases. Arch Orthop Trauma Surg. Aug 11 2009;[Medline].

  11. Krishnan KG, Schackert G. An analysis of results after selective tendon transfers through the interosseous membrane to provide selective finger and thumb extension in chronic irreparable radial nerve lesions. J Hand Surg [Am]. Feb 2008;33(2):223-31. [Medline].

  12. Bishop J, Ring D. Management of radial nerve palsy associated with humeral shaft fracture: a decision analysis model. J Hand Surg Am. Jul-Aug 2009;34(6):991-6.e1. [Medline].

  13. Hak DJ. Radial nerve palsy associated with humeral shaft fractures. Orthopedics. Feb 2009;32(2):111. [Medline].

  14. Wang JP, Shen WJ, Chen WM, Huang CK, Shen YS, Chen TH. Iatrogenic radial nerve palsy after operative management of humeral shaft fractures. J Trauma. Mar 2009;66(3):800-3. [Medline].

  15. Campbell WW. Focal neuropathies. In: Campbell WW, ed. Essentials of Electrodiagnostic Medicine. Baltimore, Md: Williams & Wilkins; 1999:255-278.

  16. Fardin P, Negrin P, Sparta S, et al. Posterior interosseous nerve neuropathy. Clinical and electromyographical aspects. Electromyogr Clin Neurophysiol. Apr-May 1992;32(4-5):229-34. [Medline].

  17. Fluri F, Lyrer P, Gratwohl A, Raetz-Bravo AE, Steck AJ. Lead poisoning from the beauty case: neurologic manifestations in an elderly woman. Neurology. Aug 28 2007;69(9):929-30. [Medline].

  18. Hanz KR, Saint-Cyr M, Semmler MJ, Rohrich RJ. Extensor tendon injuries: acute management and secondary reconstruction. Plast Reconstr Surg. Mar 2008;121(3):109e-120e. [Medline].

  19. Leis AA, Wells KJ. Radial nerve cutaneous innervation to the ulnar dorsum of the hand. Clin Neurophysiol. Mar 2008;119(3):662-6. [Medline].

  20. Malikowski T, Micklesen PJ, Robinson LR. Prognostic values of electrodiagnostic studies in traumatic radial neuropathy. Muscle Nerve. Sep 2007;36(3):364-7. [Medline].

  21. Pollock FH, Drake D, Bovill EG, et al. Treatment of radial neuropathy associated with fractures of the humerus. J Bone Joint Surg Am. Feb 1981;63(2):239-43. [Medline].

  22. Shapiro BE, Preston DC. Entrapment and compressive neuropathies. Med Clin North Am. May 2003;87(3):663-96, viii. [Medline].

  23. Stone DA, Laureno R. Handcuff neuropathies. Neurology. Jan 1991;41(1):145-7. [Medline].

  24. Turner OA, Taslitz N, Ward S. The radial nerve. In: Handbook of Peripheral Nerve Entrapments. Clifton, NJ: Humana Press; 1990:79-91.

  25. Walczyk S, Pieniazek M, Pelczar-Pieniazek M, Tabasz M. Appropriateness and effectiveness of physiotherapeutic treatment procedure after tendon transfer in patients with irreversible radial nerve injury. Ortop Traumatol Rehabil. Apr 30 2005;7(2):187-97. [Medline].

Previous
Next
 
The Radial Nerve from Gray's Anatomy (published 1918, public domain, copyright expired).
 
 
 
All material on this website is protected by copyright, Copyright © 1994-2012 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.

DISCLAIMER: The content of this Website is not influenced by sponsors. The site is designed primarily for use by qualified physicians and other medical professionals. The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for educational and informational purposes only. In no way should it be considered as offering medical advice. Please check with a physician if you suspect you are ill.