eMedicine Specialties > Neurology > Headache and Pain

Migraine Headache: Follow-up

Author: Jasvinder Chawla, MBBS, MD, MBA, Chief of Neurology, Hines Veterans Affairs Hospital; Associate Professor and Director, Neurology Residency Training Program, Loyola University Medical Center
Contributor Information and Disclosures

Updated: Sep 4, 2008

Follow-up

Further Inpatient Care

Inpatient care for migraine may be indicated for the following:

  • Treatment of severe nausea, vomiting, and subsequent dehydration
  • Treatment of severe refractory migraine pain (ie, status migrainosus)
  • Detoxification from overuse of combination analgesics, ergots, or opioids

Further Outpatient Care

Many age related factors influence the clinical expression of headache and these should be taken into account in the diagnosis as well as treatment of patients with juvenile headaches.

Inpatient & Outpatient Medications

For recommended medications in comorbid conditions, see Table 3.

Deterrence/Prevention

See Treatment for information on migraine prophylaxis.

Complications

Ischemic stroke may occur as a rare but serious complication of migraine. Risk factors for stroke include migraine with aura, female sex, cigarette smoking, and estrogen use.

Patient Education

For excellent patient education resources, see eMedicine's Headache Center. Also, visit eMedicine's patient education articles Causes and Treatments of Migraine and Related Headaches, Migraine Headache, Alternative and Complementary Approaches to Migraine and Cluster Headaches, Migraine Headache FAQs, and Understanding Migraine and Cluster Headache Medications.

 
Acknowledgments

The authors and editors of eMedicine gratefully acknowledge the contributions of previous author Amelito Malapira, MD and Jorge E Mendizabal, MDto the development and writing of this article.



More on Migraine Headache

Overview: Migraine Headache
Differential Diagnoses & Workup: Migraine Headache
Treatment & Medication: Migraine Headache
Follow-up: Migraine Headache
Multimedia: Migraine Headache
References

References

  1. Perciaccante A. Migraine is characterized by a cardiac autonomic dysfunction. Headache. Jun 2008;48(6):973. [Medline].

  2. Harling DW, Peatfield RC, Van Hille PT. Thunderclap headache: is it migraine?. Cephalalgia. Jun 1989;9(2):87-90. [Medline].

  3. Forsyth PA, Posner JB. Headaches in patients with brain tumors: a study of 111 patients. Neurology. Sep 1993;43(9):1678-83. [Medline].

  4. Agarwal S, Magu S, Kamal K. Reversible white matter abnormalities in a patient with migraine. Neurol India. Apr-Jun 2008;56(2):182-5. [Medline].

  5. Guyuron B, Kriegler JS, Davis J. Comprehensive surgical treatment of migraine headaches. Plast Reconstr Surg. Jan 2005;115(1):1-9. [Medline].

  6. Dirnberger F, Becker K. Surgical treatment of migraine headaches by corrugator muscle resection. Plast Reconstr Surg. Sep 1 2004;114(3):652-7; discussion 658-9. [Medline].

  7. Conway S, Delplanche C, Crowder J. Botox therapy for refractory chronic migraine. Headache. Apr 2005;45(4):355-7. [Medline].

  8. Schulte-Mattler WJ, Martinez-Castrillo JC. Botulinum toxin therapy of migraine and tension-type headache: comparing different botulinum toxin preparations. Eur J Neurol. Feb 2006;13 Suppl 1:51-4. [Medline].

  9. [Best Evidence] Brandes JL, Kudrow D, Stark SR, O'Carroll CP, Adelman JU, O'Donnell FJ, et al. Sumatriptan-naproxen for acute treatment of migraine: a randomized trial. JAMA. Apr 4 2007;297(13):1443-54. [Medline].

  10. Anand KS, Prasad A, Singh MM. Botulinum toxin type a in prophylactic treatment of migraine. Am J Ther. May-Jun 2006;13(3):183-7. [Medline].

  11. Aurora S. Botulinum toxin type A for the treatment of migraine. Expert Opin Pharmacother. Jun 2006;7(8):1085-95. [Medline].

  12. Biousse V, D'Anglejan-Chatillon J, Massiou H, Bousser MG. Head pain in non-traumatic carotid artery dissection: a series of 65 patients. Cephalalgia. Feb 1994;14(1):33-6. [Medline].

  13. Busch V, Gaul C. Exercise in migraine therapy--is there any evidence for efficacy? A critical review. Headache. Jun 2008;48(6):890-9. [Medline].

  14. Cutrer FM, Moskowitz MA. Wolff Award 1996. The actions of valproate and neurosteroids in a model of trigeminal pain. Headache. Nov-Dec 1996;36(10):579-85. [Medline].

  15. Dennis M, Warlow C. Migraine aura without headache: transient ischaemic attack or not?. J Neurol Neurosurg Psychiatry. Jun 1992;55(6):437-40. [Medline].

  16. Evans RW, Rosen N. Expert opinion: migraine, psychiatric comorbidities, and treatment. Headache. Jun 2008;48(6):952-8. [Medline].

  17. Fisher CM. Late-life migraine accompaniments--further experience. Stroke. Sep-Oct 1986;DA - 19861119(5):1033-42. [Medline].

  18. [Best Evidence] Freitag F, Diamond M, Diamond S, Janssen I, Rodgers A, Skobieranda F. Efficacy and tolerability of coadministration of rizatriptan and acetaminophen vs rizatriptan or acetaminophen alone for acute migraine treatment. Headache. Jun 2008;48(6):921-30. [Medline].

  19. Hazard E, Munakata J, Bigal ME, Rupnow MF, Lipton RB. The Burden of Migraine in the United States: Current and Emerging Perspectives on Disease Management and Economic Analysis. Value Health. Jul 30 2008;[Medline].

  20. Ingvardsen BK, Laursen H, Olsen UB, Hansen AJ. Possible mechanism of c-fos expression in trigeminal nucleus caudalis following cortical spreading depression. Pain. Sep 1997;72(3):407-15. [Medline].

  21. Kawabe K, Ikeda K, Igarashi O, Iwasaki Y. Vertigo, dizziness, and syncope in migraine. Headache. Jun 2008;48(6):973-4. [Medline].

  22. Lauritzen M. Pathophysiology of the migraine aura. The spreading depression theory. Brain. Feb 1994;117 (Pt 1):199-210. [Medline].

  23. Lipton RB, Stewart WF. Migraine headaches: epidemiology and comorbidity. Clin Neurosci. 1998;5(1):2-9. [Medline].

  24. Mathew NT, Kurman R, Perez F. Drug induced refractory headache--clinical features and management. Headache. Oct 1990;30(10):634-8. [Medline].

  25. Moskowitz MA, Nozaki K, Kraig RP. Neocortical spreading depression provokes the expression of c-fos protein-like immunoreactivity within trigeminal nucleus caudalis via trigeminovascular mechanisms. J Neurosci. Mar 1993;13(3):1167-77. [Medline].

  26. Olesen J. Synthesis of migraine mechanisms. In: Olesen J, Tfelt-Hansen P, Welch KMA, eds. The Headaches. New York: Raven; 1993:247-54.

  27. Olesen J, Friberg L, Olsen TS. Timing and topography of cerebral blood flow, aura, and headache during migraine attacks. Ann Neurol. Dec 1990;28(6):791-8. [Medline].

  28. Ramadan NM, Schultz LL, Gilkey SJ. Migraine prophylactic drugs: proof of efficacy, utilization and cost. Cephalalgia. Apr 1997;17(2):73-80. [Medline].

  29. Rapoport AM. Pharmacological prevention of migraine. Clin Neurosci. 1998;5(1):55-9. [Medline].

  30. Raps EC, Rogers JD, Galetta SL. The clinical spectrum of unruptured intracranial aneurysms. Arch Neurol. Mar 1993;50(3):265-8. [Medline].

  31. Raskin NH, Hosobuchi Y, Lamb S. Headache may arise from perturbation of brain. Headache. Sep 1987;27(8):416-20. [Medline].

  32. Rothrock JF, Reed RC. Preventive Migraine Therapy. Abcomm, Inc.; 1998:1-16.

  33. Silberstein S, Diener HC, Lipton R, Goadsby P, Dodick D, Bussone G, et al. Epidemiology, risk factors, and treatment of chronic migraine: a focus on topiramate. Headache. Jul 2008;48(7):1087-95. [Medline].

  34. Silberstein SD. Agents for migraine and other headaches. In: Rowland LP, ed. Current Neurologic Drugs. Philadelphia: William & Wilkins; 1998:24-81.

  35. Silberstein SD. Evaluation and emergency treatment of headache. Headache. Sep 1992;32(8):396-407. [Medline].

  36. Silberstein SD. Preventive treatment of migraine: an overview. Cephalalgia. Apr 1997;17(2):67-72. [Medline].

  37. Silberstein SD, Lipton RB. Overview of diagnosis and treatment of migraine. Neurology. Oct 1994;44(10 Suppl 7):S6-16. [Medline].

  38. Silberstein SD, Lipton RB, Goadsby PJ. Headache in Clinical Practice. Oxford: Isis Medical Media Ltd; 1998:31-40, 41-60, 61-90.

  39. Stewart WF, Shechter A, Lipton RB. Migraine heterogeneity. Disability, pain intensity, and attack frequency and duration. Neurology. Jun 1994;44(6 Suppl 4):S24-39. [Medline].

  40. Termine C, Ferri M, Balottin U. Acute treatment of migraine in children and adolescents. Funct Neurol. Apr-Jun 2008;23(2):63-9. [Medline].

  41. Tfelt-Hansen P, Lipton RB. Prioritizing acute pharmacotherapy. In: Olesen J, Tfelt-Hansen P, Welch KMA, eds. The Headaches. New York: Raven; 1993:359-62.

  42. Tfelt-Hansen P, Stewrt Johnson E. Nonsteroidal antiinflammatory drugs in the treatment of the acute migraine attack. In: Olesen J, Tfelt-Hansen P, Welch KMA, eds. The Headaches. New York: Raven; 1993:305-12.

  43. Tfelt-Hansen P, Welch KMA. Prioritizing prophylactic treatment. In: Olesen J, Tfelt-Hansen P, Welch KMA, eds. The Headaches. New York: Raven; 1993:403-4.

  44. Vermeulen M, van Gijn J. The diagnosis of subarachnoid haemorrhage. J Neurol Neurosurg Psychiatry. May 1990;53(5):365-72. [Medline].

  45. Ward TN. Management of an acute primary headache. Clin Neurosci. 1998;5(1):50-4. [Medline].

  46. Weiller C, May A, Limmroth V. Brain stem activation in spontaneous human migraine attacks. Nat Med. Jul 1995;1(7):658-60. [Medline].

  47. Wijdicks EF, Kerkhoff H, van Gijn J. Long-term follow-up of 71 patients with thunderclap headache mimicking subarachnoid haemorrhage. Lancet. Jul 9 1988;2(8602):68-70. [Medline].

  48. Woods RP, Iacoboni M, Mazziotta JC. Brief report: bilateral spreading cerebral hypoperfusion during spontaneous migraine headache. N Engl J Med. Dec 22 1994;331(25):1689-92. [Medline].

Further Reading

Keywords

complex migraine, migraine equivalent, migraine variant, classic migraine, cluster headache, aura

Contributor Information and Disclosures

Author

Jasvinder Chawla, MBBS, MD, MBA, Chief of Neurology, Hines Veterans Affairs Hospital; Associate Professor and Director, Neurology Residency Training Program, Loyola University Medical Center
Jasvinder Chawla, MBBS, MD, MBA is a member of the following medical societies: American Academy of Neurology, American Association of Neuromuscular and Electrodiagnostic Medicine, American Clinical Neurophysiology Society, and American Medical Association
Disclosure: Nothing to disclose.

Medical Editor

Joseph Quinn, MD, Assistant Professor, Department of Neurology, Portland VA Medical Center, Oregon Health Sciences University
Joseph Quinn, MD is a member of the following medical societies: American Academy of Neurology, Society for Neuroscience, and Society for Pediatric Radiology
Disclosure: Nothing to disclose.

Pharmacy Editor

Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine
Disclosure: eMedicine Salary Employment

Managing Editor

James H Halsey, MD, Professor, Department of Neurology, University of Alabama Medical Center
James H Halsey, MD is a member of the following medical societies: American Academy of Neurology, American Heart Association, American Medical Association, American Neurological Association, American Society of Neuroimaging, Medical Association of the State of Alabama, New York Academy of Sciences, Pan American Medical Association, Sigma Xi, Society for Neuroscience, and Southern Medical Association
Disclosure: Nothing to disclose.

CME Editor

Matthew J Baker, MD, Consulting Staff, Collier Neurologic Specialists, Naples Community Hospital
Matthew J Baker, MD is a member of the following medical societies: American Academy of Neurology
Disclosure: Nothing to disclose.

Chief Editor

Helmi L Lutsep, MD, Professor, Department of Neurology, Oregon Health & Science University; Associate Director, Oregon Stroke Center
Helmi L Lutsep, MD is a member of the following medical societies: American Academy of Neurology and American Stroke Association
Disclosure: Co-Axia Consulting fee Review panel membership; Talecris Consulting fee Review panel membership; AGA Medical Consulting fee Review panel membership; Boehringer Ingelheim Honoraria Speaking and teaching; Concentric Medical Consulting fee Review panel membership; Abbott Consulting fee Consulting; Sanofi  Consulting

 
 
HONcode

We subscribe to the
HONcode principles of the
Health On the Net Foundation

All material on this website is protected by copyright, Copyright© 1994- by Medscape.
This website also contains material copyrighted by 3rd parties.

DISCLAIMER: The content of this Website is not influenced by sponsors. The site is designed primarily for use by qualified physicians and other medical professionals. The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for educational and informational purposes only. In no way should it be considered as offering medical advice. Please check with a physician if you suspect you are ill.