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Paraneoplastic Cerebellar Degeneration: Multimedia
Updated: Jul 13, 2009
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| Follow-up: Paraneoplastic Cerebellar Degeneration |
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References
Lorusso L, Hart IK, Giometto B, et al. Immunological features of neurological paraneoplastic syndromes. Int J Immunopathol Pharmacol. May-Aug 2004;17(2):135-44. [Medline].
BRAIN WR, DANIEL PM, GREENFIELD JG. Subacute cortical cerebellar degeneration and its relation to carcinoma. J Neurol Neurosurg Psychiatry. May 1951;14(2):59-75. [Medline].
Posner JB. Paraneoplastic cerebellar degeneration. Can J Neurol Sci. May 1993;20 Suppl 3:S117-22. [Medline].
Inuzuka T. Autoantibodies in paraneoplastic neurological syndrome. Am J Med Sci. Apr 2000;319(4):217-26. [Medline].
Bolla L, Palmer RM. Paraneoplastic cerebellar degeneration. Case report and literature review. Arch Intern Med. Jun 9 1997;157(11):1258-62. [Medline].
Nath U, Grant R. Neurological paraneoplastic syndromes. J Clin Pathol. Dec 1997;50(12):975-80. [Medline].
Albert ML, Austin LM, Darnell RB. Detection and treatment of activated T cells in the cerebrospinal fluid of patients with paraneoplastic cerebellar degeneration. Ann Neurol. Jan 2000;47(1):9-17. [Medline].
Okano HJ, Park WY, Corradi JP, Darnell RB. The cytoplasmic Purkinje onconeural antigen cdr2 down-regulates c-Myc function: implications for neuronal and tumor cell survival. Genes Dev. Aug 15 1999;13(16):2087-97. [Medline].
Rojas I, Graus F, Keime-Guibert F, et al. Long-term clinical outcome of paraneoplastic cerebellar degeneration and anti-Yo antibodies. Neurology. Sep 12 2000;55(5):713-5. [Medline].
Schmahmann JD, Sherman JC. The cerebellar cognitive affective syndrome. Brain. Apr 1998;121 ( Pt 4):561-79. [Medline].
Peterson K, Rosenblum MK, Kotanides H, Posner JB. Paraneoplastic cerebellar degeneration. I. A clinical analysis of 55 anti-Yo antibody-positive patients. Neurology. Oct 1992;42(10):1931-7. [Medline].
Tanaka M, Tanaka K, Shinozawa K, et al. Cytotoxic T cells react with recombinant Yo protein from a patient with paraneoplastic cerebellar degeneration and anti-Yo antibody. J Neurol Sci. Nov 26 1998;161(1):88-90. [Medline].
Greenlee JE, Brashear HR. Antibodies to cerebellar Purkinje cells in patients with paraneoplastic cerebellar degeneration and ovarian carcinoma. Ann Neurol. Dec 1983;14(6):609-13. [Medline].
Jaeckle KA, Graus F, Houghton A. Autoimmune response of patients with paraneoplastic cerebellar degeneration to a Purkinje cell cytoplasmic protein antigen. Ann Neurol. Nov 1985;18(5):592-600. [Medline].
Mason WP, Graus F, Lang B, Honnorat J, Delattre JY, Valldeoriola F. Small-cell lung cancer, paraneoplastic cerebellar degeneration and the Lambert-Eaton myasthenic syndrome. Brain. Aug 1997;120 ( Pt 8):1279-300. [Medline].
Wilkinson PC, Zeromski J. Immunofluorescent detection of antibodies against neurones in sensory carcinomatous neuropathy. Brain. Sep 1965;88(3):529-83. [Medline].
Graus F, Cordon-Cardo C, Posner JB. Neuronal antinuclear antibody in sensory neuronopathy from lung cancer. Neurology. Apr 1985;35(4):538-43. [Medline].
Graus F, Elkon KB, Cordon-Cardo C, Posner JB. Sensory neuronopathy and small cell lung cancer. Antineuronal antibody that also reacts with the tumor. Am J Med. Jan 1986;80(1):45-52. [Medline].
Dalmau J, Gonzalez RG, Lerwill MF. Case records of the Massachusetts General Hospital. Case 4-2007. A 56-year-old woman with rapidly progressive vertigo and ataxia. N Engl J Med. Feb 8 2007;356(6):612-20. [Medline].
Rosenfeld MR, Dalmau J. Current Therapies for Paraneoplastic Neurologic Syndromes. Curr Treat Options Neurol. Jan 2003;5(1):69-77. [Medline].
Bataller L, Dalmau J. Paraneoplastic neurologic syndromes: approaches to diagnosis and treatment. Semin Neurol. Jun 2003;23(2):215-24. [Medline].
Dalmau JO, Posner JB. Paraneoplastic syndromes. Arch Neurol. Apr 1999;56(4):405-8. [Medline].
Darnell RB. The importance of defining the paraneoplastic neurologic disorders. N Engl J Med. Jun 10 1999;340(23):1831-3. [Medline].
Darnell RB, Posner JB. Paraneoplastic syndromes involving the nervous system. N Engl J Med. Oct 16 2003;349(16):1543-54. [Medline].
Graus F, Delattre JY, Antoine JC, et al. Recommended diagnostic criteria for paraneoplastic neurological syndromes. J Neurol Neurosurg Psychiatry. Aug 2004;75(8):1135-40. [Medline].
Greenlee JE. Cytotoxic T cells in paraneoplastic cerebellar degeneration. Ann Neurol. Jan 2000;47(1):4-5. [Medline].
Greenlee JE, Brashear HR, Jaeckle KA, et al. Pursuing an occult carcinoma in a patient with subacute cerebellar degeneration and anticerebellar antibodies. Need for vigorous follow-up. West J Med. Feb 1992;156(2):199-202. [Medline].
Jaeckle KA. Paraneoplastic nervous system syndromes. Curr Opin Oncol. May 1996;8(3):204-8. [Medline].
Pittock SJ, Kryzer TJ, Lennon VA. Paraneoplastic antibodies coexist and predict cancer, not neurological syndrome. Ann Neurol. Nov 2004;56(5):715-9. [Medline].
Rousseau A, Benyahia B, Dalmau J, Connan F, Guillet JG, Delattre JY, et al. T cell response to Hu-D peptides in patients with anti-Hu syndrome. J Neurooncol. Feb 2005;71(3):231-6. [Medline].
Sommer C, Weishaupt A, Brinkhoff J, Biko L, Wessig C, Gold R. Paraneoplastic stiff-person syndrome: passive transfer to rats by means of IgG antibodies to amphiphysin. Lancet. Apr 16-22 2005;365(9468):1406-11. [Medline].
Voltz RD, Posner JB, Dalmau J, Graus F. Paraneoplastic encephalomyelitis: an update of the effects of the anti- Hu immune response on the nervous system and tumour. J Neurol Neurosurg Psychiatry. Aug 1997;63(2):133-6. [Medline].
Further Reading
Keywords
paraneoplastic neurologic syndrome, PCD, breast cancer, ovarian cancer, uterine cancer, lung cancer, occult gynecologic cancers, malignancy, paraneoplastic cerebellar degeneration




Multimedia: Paraneoplastic Cerebellar Degeneration