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Primary Malignant Skull Tumors Follow-up

  • Author: Draga Jichici, MD, FRCP, FAHA; Chief Editor: Tarakad S Ramachandran, MBBS, MBA, MPH, FAAN, FACP, FAHA, FRCP, FRCPC, FRS, LRCP, MRCP, MRCS  more...
Updated: Dec 11, 2014

Further Outpatient Care

See the list below:

  • Postoperative
  • Radiation therapy
  • Chemotherapy

Further Inpatient Care

See the list below:

  • Postoperative
  • Chemotherapy


See the list below:

  • Postoperative complications
    • Cranial nerve palsy
    • Meningitis
    • Paralysis
    • Cognitive dysfunction
  • Carcinomatous meningitis
  • Wound infection
  • Immunosuppression due to chemotherapy and radiation therapy
  • Recurrence
  • Metastasis


See the list below:

  • Osteosarcoma has a 5-year survival rate between 20% and 50%.
  • Chondrosarcoma has a 10-year survival rate of 30-80%, depending on the grade of the initial tumor.
  • Fibrosarcomas metastasize in 50% of cases, and the 10-year survival rate is 40%.
  • Ewing sarcoma has a 5-year survival rate of 40-65%.
  • Giant cell tumor has a recurrence rate of 30% in 2 years, but otherwise its prognosis is relatively good.
  • Angiosarcomas, if properly treated, have a cure rate of about 50%.
  • Chordomas, although difficult to resect completely, are slow-growing tumors and have a 5-year survival rate of 40%.
  • Myeloma survival rates vary depending on the grade. However, even in patients with widespread disease, complete remission can be achieved for up to 2-3 years (or longer).

Patient Education

See the list below:

  • The lesion should be identified and treated promptly.
  • If required, patients should be referred for psychological counseling.
Contributor Information and Disclosures

Draga Jichici, MD, FRCP, FAHA Associate Clinical Professor, Department of Neurology and Critical Care Medicine, McMaster University School of Medicine, Canada

Draga Jichici, MD, FRCP, FAHA is a member of the following medical societies: American Academy of Neurology, Royal College of Physicians and Surgeons of Canada, Canadian Medical Protective Association, Canadian Medical Protective Association, Neurocritical Care Society, Canadian Critical Care Society, Canadian Critical Care Society, Canadian Neurocritical Care Society, Canadian Neurological Sciences Federation

Disclosure: Nothing to disclose.

Specialty Editor Board

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

Jorge C Kattah, MD Head, Associate Program Director, Professor, Department of Neurology, University of Illinois College of Medicine at Peoria

Jorge C Kattah, MD is a member of the following medical societies: American Academy of Neurology, American Neurological Association, New York Academy of Sciences

Disclosure: Nothing to disclose.

Chief Editor

Tarakad S Ramachandran, MBBS, MBA, MPH, FAAN, FACP, FAHA, FRCP, FRCPC, FRS, LRCP, MRCP, MRCS Professor Emeritus of Neurology and Psychiatry, Clinical Professor of Medicine, Clinical Professor of Family Medicine, Clinical Professor of Neurosurgery, State University of New York Upstate Medical University; Neuroscience Director, Department of Neurology, Crouse Irving Memorial Hospital

Tarakad S Ramachandran, MBBS, MBA, MPH, FAAN, FACP, FAHA, FRCP, FRCPC, FRS, LRCP, MRCP, MRCS is a member of the following medical societies: American College of International Physicians, American Heart Association, American Stroke Association, American Academy of Neurology, American Academy of Pain Medicine, American College of Forensic Examiners Institute, National Association of Managed Care Physicians, American College of Physicians, Royal College of Physicians, Royal College of Physicians and Surgeons of Canada, Royal College of Surgeons of England, Royal Society of Medicine

Disclosure: Nothing to disclose.

Additional Contributors

Spiros Manolidis, MD Associate Professor of Otolaryngology and Neurological Surgery, Columbia University

Spiros Manolidis, MD is a member of the following medical societies: American Academy of Otolaryngology-Head and Neck Surgery, American Auditory Society, American Head and Neck Society, American Medical Association, Canadian Society of Otolaryngology-Head & Neck Surgery, Society of University Otolaryngologists-Head and Neck Surgeons, Texas Medical Association

Disclosure: Nothing to disclose.


The authors and editors of Medscape Reference gratefully acknowledge the contributions of previous author Efstathios Papavassiliou, MD to the development and writing of this article.

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Head CT scan of a 60-year-old man with a history of multiple myeloma for 2 years, showing multiple lytic lesions that involve both the inner and outer tables as well as the diploë.
This head CT scan shows multiple lytic lesions of the skull involving both the inner and outer tables.
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