eMedicine Specialties > Neurology > Neurological Infections

Leprosy: Multimedia

Author: Ramaratnam Sridharan, MBBS, MD, Head, Department of Neurology, Professor of Neurology, Chennai Neurospeciality and Research Institute, India
Coauthor(s): Nicholas Y Lorenzo, MD, Chief Editor, eMedicine Neurology; Consulting Staff, Neurology Specialists and Consultants; Lakshmi Narasimhan Ranganathan, MD, Tutor, Institute Of Mental Health, Chennai, India; Senior Civil Assistant Surgeon, Tamil Nadu Medical Services; Srinivasaraman Govindarajan, DMRD, DNB, Fellow in Radiology, Barnard Institute of Radiology, India
Contributor Information and Disclosures

Updated: Feb 27, 2007

Multimedia

Infiltrated, scaly skin patch, with thickening of...
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Media file 1: Infiltrated, scaly skin patch, with thickening of the cutaneous nerve close to the patch, in a patient with tuberculoid leprosy.
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Infiltrated, scaly skin patch, with thickening of...

Infiltrated, scaly skin patch, with thickening of the cutaneous nerve close to the patch, in a patient with tuberculoid leprosy.

Patient with lepromatous leprosy showing multiple...
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Media file 2: Patient with lepromatous leprosy showing multiple skin nodules with diffuse infiltration.
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Patient with lepromatous leprosy showing multiple...

Patient with lepromatous leprosy showing multiple skin nodules with diffuse infiltration.

Infiltration of the ear lobes in a patient with l...
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Media file 3: Infiltration of the ear lobes in a patient with lepromatous leprosy.
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Infiltration of the ear lobes in a patient with l...

Infiltration of the ear lobes in a patient with lepromatous leprosy.

Advanced lepromatous leprosy with amputation of t...
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Media file 4: Advanced lepromatous leprosy with amputation of toes and trophic ulceration.
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Advanced lepromatous leprosy with amputation of t...

Advanced lepromatous leprosy with amputation of toes and trophic ulceration.

Bilateral total claw hand.
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Media file 5: Bilateral total claw hand.
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Bilateral total claw hand.

Bilateral total claw hand.

Anteroposterior (AP) radiograph of the foot shows...
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Media file 6: Anteroposterior (AP) radiograph of the foot shows absence of the second to fifth toes and distal tapering of the metatarsals secondary to neuropathy; this is the licked–candy stick appearance. The phalanges of the great toe show destruction secondary to osteomyelitis
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Anteroposterior (AP) radiograph of the foot shows...

Anteroposterior (AP) radiograph of the foot shows absence of the second to fifth toes and distal tapering of the metatarsals secondary to neuropathy; this is the licked–candy stick appearance. The phalanges of the great toe show destruction secondary to osteomyelitis

Sagittal fat-saturated T2-weighted image shows am...
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Media file 7: Sagittal fat-saturated T2-weighted image shows amputation of the great toe with increased signal intensity in the head of the first metatarsal indicating osteomyelitis. A small abscess is noted beneath the head of the first metatarsal.
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Sagittal fat-saturated T2-weighted image shows am...

Sagittal fat-saturated T2-weighted image shows amputation of the great toe with increased signal intensity in the head of the first metatarsal indicating osteomyelitis. A small abscess is noted beneath the head of the first metatarsal.

More on Leprosy

Overview: Leprosy
Differential Diagnoses & Workup: Leprosy
Treatment & Medication: Leprosy
Follow-up: Leprosy
Multimedia: Leprosy
References
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References

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  19. Mohanty KK, Joshi B, Katoch K, Sengupta U. Leprosy reactions: humoral and cellular immune responses to M. leprae, 65kDa, 28kDa, and 18 kDa antigens. Int J Lepr Other Mycobact Dis. Jun 2004;72(2):149-58. [Medline].

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  25. WHO. World Health Organization (WHO) Leprosy Elimination Programme (LEP). Elimination of Leprosy as a Public Health Problem. Available at www.who.int/lep. [Full Text].

  26. Waters MFR. Recent developments in leprosy research. In: Chopra JS, Jagannathan K, Sawhney IMS. Advances in Neurology. Amersterdam, the Netherlands: Excerpta Medica;. 1990;273-82.

  27. Zhang L, Namisato M, Matsuoka M. A mutation at codon 516 in the rpoB gene of Mycobacterium leprae confers resistance to rifampin. Int J Lepr Other Mycobact Dis. Dec 2004;72(4):468-72. [Medline].

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Further Reading

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Keywords

leprosy, Hansen's disease, Hansen disease, Mycobacterium leprae, M leprae, tuberculoid leprosy, TT leprosy, lepromatous leprosy, LL leprosy, tuberculoid leprosy, BT leprosy, midborderline leprosy, BB leprosy, borderline lepromatous leprosy, BL leprosy, paucibacillary leprosy, PB leprosy, multibacillary leprosy, MB leprosy, erythema nodosum leprosum, ENL

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Contributor Information and Disclosures

Author

Ramaratnam Sridharan, MBBS, MD, Head, Department of Neurology, Professor of Neurology, Chennai Neurospeciality and Research Institute, India
Ramaratnam Sridharan, MBBS, MD is a member of the following medical societies: American Academy of Neurology
Disclosure: Nothing to disclose.

Coauthor(s)

Nicholas Y Lorenzo, MD, Chief Editor, eMedicine Neurology; Consulting Staff, Neurology Specialists and Consultants
Nicholas Y Lorenzo, MD is a member of the following medical societies: Alpha Omega Alpha and American Academy of Neurology
Disclosure: Nothing to disclose.

Lakshmi Narasimhan Ranganathan, MD, Tutor, Institute Of Mental Health, Chennai, India; Senior Civil Assistant Surgeon, Tamil Nadu Medical Services
Disclosure: Nothing to disclose.

Srinivasaraman Govindarajan, DMRD, DNB, Fellow in Radiology, Barnard Institute of Radiology, India
Disclosure: Nothing to disclose.

Medical Editor

Marion Priscilla Short, MD, Assistant Professor, Departments of Neurology, Pediatrics, and Pathology, University of Chicago Hospitals and Clinics
Marion Priscilla Short, MD is a member of the following medical societies: American Academy of Neurology, American Association of Neuropathologists, American College of Medical Genetics, American Medical Association, and American Society of Human Genetics
Disclosure: Nothing to disclose.

Pharmacy Editor

Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine
Disclosure: Nothing to disclose.

Managing Editor

Glenn Lopate, MD, Associate Professor, Department of Neurology, Division of Neuromuscular Diseases, Washington University School of Medicine; Chief of Neurology, St Louis ConnectCare, Consulting Staff, Barnes Jewish Hospital
Glenn Lopate, MD is a member of the following medical societies: American Academy of Neurology, American Association of Neuromuscular and Electrodiagnostic Medicine, and Phi Beta Kappa
Disclosure: Nothing to disclose.

CME Editor

Matthew J Baker, MD, Consulting Staff, Collier Neurologic Specialists, Naples Community Hospital
Matthew J Baker, MD is a member of the following medical societies: American Academy of Neurology
Disclosure: Nothing to disclose.

Chief Editor

Michael K Racke, MD, Professor, Neurology and Molecular Virology, Immunology, and Medical Genetics; Chairman of Neurology, Chief, Neurology Service, Ohio State University Medical Center
Michael K Racke, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Neurology, American Association for the Advancement of Science, American Association of Immunologists, and American Neurological Association
Disclosure: Teva Neuroscience Consulting fee Consulting; Peptimmune Inc. Consulting fee Consulting; Bristol Myers Squibb Consulting fee Consulting; EMD Serono Honoraria Speaking and teaching

 
 
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