eMedicine Specialties > Neurology > Neurological Infections
HIV-1 Associated Vacuolar Myelopathy: Follow-up
Updated: Mar 14, 2007
Follow-up
Further Outpatient Care
- Coordinate care with the primary care physician and an infectious disease specialist.
Prognosis
- The prognosis is poor.
Patient Education
- For excellent patient education resources, visit eMedicine's Immune System Center, Dementia Center, and Sexually Transmitted Diseases Center. Also, see eMedicine's patient education articles Dementia Due to HIV Infection and HIV/AIDS.
Miscellaneous
Medicolegal Pitfalls
- Failure to exclude other causes of myelopathy related or unrelated to HIV infection, since HIV-related vacuolar myelopathy is a diagnosis of exclusion
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Follow-up: HIV-1 Associated Vacuolar Myelopathy |
| Multimedia: HIV-1 Associated Vacuolar Myelopathy |
| References |
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References
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Di Rocco A, Tagliati M, Danisi F, et al. A pilot study of L-methionine for the treatment of AIDS-associated myelopathy. Neurology. Jul 1998;51(1):266-8. [Medline].
Di Rocco A, Werner P, Bottiglieri T, et al. Treatment of AIDS-associated myelopathy with L-methionine: a placebo-controlled study. Neurology. Oct 12 2004;63(7):1270-5. [Medline].
DiRocco A. HIV-associated myelopathy. Current Treatment Options in Infectious Diseases. Vol 5. 2003:457-465.
Eilbott DJ, Peress N, Burger H, et al. Human immunodeficiency virus type 1 in spinal cords of acquired immunodeficiency syndrome patients with myelopathy: expression and replication in macrophages. Proc Natl Acad Sci U S A. May 1989;86(9):3337-41. [Medline].
Fernandez-Fernandez FJ, de la Fuente-Aguado J, Ocampo-Hermida A. Remission of HIV-associated myelopathy after highly active antiretroviraltherapy. J Postgrad Med. 2004;50(3):195-6. [Medline].
Gendelman HE, Lipton SA, Epstein L. The Neurology of AIDS. New York: Chapman & Hall;1998.
Petito CK, Navia BA, Cho ES, et al. Vacuolar myelopathy pathologically resembling subacute combined degeneration in patients with the acquired immunodeficiency syndrome. N Engl J Med. Apr 4 1985;312(14):874-9. [Medline].
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Sartoretti-Schefer S, Blattler T, Wichmann W. Spinal MRI in vacuolar myelopathy, and correlation with histopathological findings. Neuroradiology. Dec 1997;39(12):865-9. [Medline].
Staudinger R, Henry K. Remission of HIV myelopathy after highly active antiretroviral therapy. Neurology. Jan 11 2000;54(1):267-8. [Medline].
Tagliati M, Di Rocco A, Danisi F, Simpson DM. The role of somatosensory evoked potentials in the diagnosis of AIDS-associated myelopathy. Neurology. Apr 11 2000;54(7):1477-82. [Medline].
Tyor WR, Glass JD, Baumrind N, et al. Cytokine expression of macrophages in HIV-1-associated vacuolar myelopathy. Neurology. May 1993;43(5):1002-9. [Medline].
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Further Reading
Keywords
HIV-1 associated myelopathy, AIDS myelopathy, AIDS dementia complex, peripheral neuropathies, opportunistic central nervous system infections, opportunistic peripheral nervous system infections, central nervous system malignancies, cytomegalovirus, progressive multifocal leukoencephalopathy, lymphoma, HIV-1 infection complications, neuropathy, HAART, highly active antiretroviral therapy
Follow-up: HIV-1 Associated Vacuolar Myelopathy