eMedicine Specialties > Neurology > Neuromuscular Diseases

Myasthenia Gravis: Multimedia

Author: Aashit K Shah, MD, Associate Professor of Neurology, Wayne State University; Program Director, Clinical Neurophysiology Fellowship, Department of Neurology, Detroit Medical Center
Contributor Information and Disclosures

Updated: Jan 15, 2009

Multimedia

Normal neuromuscular junction showing a presynapt...Media file 1: Normal neuromuscular junction showing a presynaptic terminal with a motor nerve ending in an enlargement (bouton terminale): Synaptic cleft and postsynaptic membrane with multiple folds and embedded with several acetylcholine receptors.
Normal neuromuscular junction showing a presynapt...

Normal neuromuscular junction showing a presynaptic terminal with a motor nerve ending in an enlargement (bouton terminale): Synaptic cleft and postsynaptic membrane with multiple folds and embedded with several acetylcholine receptors.

Acetylcholine receptor. Note 5 subunits, each wit...Media file 2: Acetylcholine receptor. Note 5 subunits, each with 4 membrane-spanning domains forming a rosette with a central opening. The central opening acts as an ion channel.
Acetylcholine receptor. Note 5 subunits, each wit...

Acetylcholine receptor. Note 5 subunits, each with 4 membrane-spanning domains forming a rosette with a central opening. The central opening acts as an ion channel.

A typical recording of compound muscle action pot...Media file 3: A typical recording of compound muscle action potentials with repetitive nerve stimulation at low frequency in a patient with myasthenia gravis. Note the gradual decline in the amplitude of the compound muscle action potential with slight improvement after the fifth or sixth potential.
A typical recording of compound muscle action pot...

A typical recording of compound muscle action potentials with repetitive nerve stimulation at low frequency in a patient with myasthenia gravis. Note the gradual decline in the amplitude of the compound muscle action potential with slight improvement after the fifth or sixth potential.

CT scan of chest showing an anterior mediastinal ...Media file 4: CT scan of chest showing an anterior mediastinal mass (thymoma) in a patient with myasthenia gravis.
CT scan of chest showing an anterior mediastinal ...

CT scan of chest showing an anterior mediastinal mass (thymoma) in a patient with myasthenia gravis.

More on Myasthenia Gravis

Overview: Myasthenia Gravis
Differential Diagnoses & Workup: Myasthenia Gravis
Treatment & Medication: Myasthenia Gravis
Follow-up: Myasthenia Gravis
Multimedia: Myasthenia Gravis
References

References

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Further Reading

Keywords

myasthenia gravis, autoimmune neuromuscular disease, skeletal muscle weakness, fatigability on exertion, muscle weakness, acetylcholine receptor, AChR, seronegative myasthenia gravis, SNMG, muscle-specific kinase, MuSK, MG

Contributor Information and Disclosures

Author

Aashit K Shah, MD, Associate Professor of Neurology, Wayne State University; Program Director, Clinical Neurophysiology Fellowship, Department of Neurology, Detroit Medical Center
Aashit K Shah, MD is a member of the following medical societies: American Academy of Neurology, American Clinical Neurophysiology Society, and American Epilepsy Society
Disclosure: Nothing to disclose.

Medical Editor

Donald B Sanders, MD, EMG Laboratory Director, Professor of Medicine (Neurology), Division of Neurology, Duke University Medical Center
Donald B Sanders, MD is a member of the following medical societies: American Academy of Neurology, American Association of Neuromuscular and Electrodiagnostic Medicine, American Neurological Association, and New York Academy of Sciences
Disclosure: Nothing to disclose.

Pharmacy Editor

Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine
Disclosure: Nothing to disclose.

Managing Editor

Glenn Lopate, MD, Associate Professor, Department of Neurology, Division of Neuromuscular Diseases, Washington University School of Medicine; Chief of Neurology, St Louis ConnectCare, Consulting Staff, Barnes Jewish Hospital
Glenn Lopate, MD is a member of the following medical societies: American Academy of Neurology, American Association of Neuromuscular and Electrodiagnostic Medicine, and Phi Beta Kappa
Disclosure: Nothing to disclose.

CME Editor

Selim R Benbadis, MD, Professor, Director of Comprehensive Epilepsy Program, Departments of Neurology and Neurosurgery, University of South Florida School of Medicine, Tampa General Hospital
Selim R Benbadis, MD is a member of the following medical societies: American Academy of Neurology, American Academy of Sleep Medicine, American Clinical Neurophysiology Society, American Epilepsy Society, and American Medical Association
Disclosure: Nothing to disclose.

Chief Editor

Nicholas Y Lorenzo, MD, Chief Editor, eMedicine Neurology; Consulting Staff, Neurology Specialists and Consultants
Nicholas Y Lorenzo, MD is a member of the following medical societies: Alpha Omega Alpha and American Academy of Neurology
Disclosure: Nothing to disclose.

 
 
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