eMedicine Specialties > Endocrinology > Adrenal Gland

Cushing Syndrome: Multimedia

Author: Gail K Adler, MD, PhD, FAHA, Assistant Professor, Department of Medicine, Division of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital, Harvard Medical School
Contributor Information and Disclosures

Updated: Oct 1, 2009

Multimedia

Physical findings in Cushing syndrome.
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Media file 1: Physical findings in Cushing syndrome.
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Physical findings in Cushing syndrome.

Physical findings in Cushing syndrome.

Diagnosis of Cushing syndrome.
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Media file 2: Diagnosis of Cushing syndrome.
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Diagnosis of Cushing syndrome.

Diagnosis of Cushing syndrome.

Etiology of Cushing syndrome.
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Media file 3: Etiology of Cushing syndrome.
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Etiology of Cushing syndrome.

Etiology of Cushing syndrome.

More on Cushing Syndrome

Overview: Cushing Syndrome
Differential Diagnoses & Workup: Cushing Syndrome
Treatment & Medication: Cushing Syndrome
Follow-up: Cushing Syndrome
Multimedia: Cushing Syndrome
References
Further Reading
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References

  1. Ilias I, Torpy DJ, Pacak K, Mullen N, Wesley RA, Nieman LK. Cushing's syndrome due to ectopic corticotropin secretion: twenty years' experience at the National Institutes of Health. J Clin Endocrinol Metab. Aug 2005;90(8):4955-62. [Medline].

  2. Flack MR, Oldfield EH, Cutler GB Jr, et al. Urine free cortisol in the high-dose dexamethasone suppression test for the differential diagnosis of the Cushing syndrome. Ann Intern Med. Feb 1 1992;116(3):211-7. [Medline].

  3. Kidambi S, Raff H, Findling JW. Limitations of nocturnal salivary cortisol and urine free cortisol in the diagnosis of mild Cushing's syndrome. Eur J Endocrinol. Dec 2007;157(6):725-31. [Medline].

  4. Tyrrell JB, Findling JW, Aron DC, Fitzgerald PA, Forsham PH. An overnight high-dose dexamethasone suppression test for rapid differential diagnosis of Cushing's syndrome. Ann Intern Med. Feb 1986;104(2):180-6. [Medline].

  5. Raff H. Utility of salivary cortisol measurements in Cushing's syndrome and adrenal insufficiency. J Clin Endocrinol Metab. Jul 14 2009;[Medline].

  6. Carroll T, Raff H, Findling JW. Late-night salivary cortisol for the diagnosis of Cushing syndrome: a meta-analysis. Endocr Pract. Jul-Aug 2009;15(4):335-42. [Medline].

  7. Chrousos GP, Gold PW. The concepts of stress and stress system disorders. Overview of physical and behavioral homeostasis. JAMA. Mar 4 1992;267(9):1244-52. [Medline].

  8. Johanssen S, Allolio B. Mifepristone (RU 486) in Cushing's syndrome. Eur J Endocrinol. Nov 2007;157(5):561-9. [Medline].

  9. Batista DL, Oldfield EH, Keil MF, et al. Postoperative testing to predict recurrent Cushing disease in children. J Clin Endocrinol Metab. Aug 2009;94(8):2757-65. [Medline].

  10. Eddy RL, Jones AL, Gilliland PF, Ibarra JD Jr, Thompson JQ, MacMurry JF Jr. Cushing's syndrome: a prospective study of diagnostic methods. Am J Med. Nov 1973;55(5):621-30. [Medline].

  11. Findling JW, Doppman JL. Biochemical and radiologic diagnosis of Cushing's syndrome. Endocrinol Metab Clin North Am. Sep 1994;23(3):511-37. [Medline].

  12. Kaye TB, Crapo L. The Cushing syndrome: an update on diagnostic tests. Ann Intern Med. Mar 15 1990;112(6):434-44. [Medline].

  13. Newell-Price J, Trainer P, Besser M, Grossman A. The diagnosis and differential diagnosis of Cushing's syndrome and pseudo-Cushing's states. Endocr Rev. Oct 1998;19(5):647-72. [Medline].

  14. Nieman L, Cutler GB Jr. Cushing's syndrome. In: Degroot LJ, Besser M, Burger HG, et al, eds. Endocrinology. 3rd ed. Philadelphia, Pa: WB Saunders; 1995:1741-69.

  15. Pavlatos FC, Smilo RP, Forsham PH. A rapid screening test for Cushing's syndrome. JAMA. Aug 30 1965;193:720-3. [Medline].

  16. Plotz CM, Knowlton AI, Ragan C. The natural history of Cushing's syndrome. Am J Med. Nov 1952;13(5):597-614. [Medline].

  17. Raff H, Findling JW. A physiologic approach to diagnosis of the Cushing syndrome. Ann Intern Med. Jun 17 2003;138(12):980-91. [Medline].

  18. Yanovski JA, Cutler GB Jr. Glucocorticoid action and the clinical features of Cushing's syndrome. Endocrinol Metab Clin North Am. Sep 1994;23(3):487-509. [Medline].

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Keywords

Cushing's syndrome, Cushing syndrome, cortisol, Cushing's disease, Cushings disease, pituitary, pituitary gland, pituitary tumor, ACTH, pituitary glands, pituitary tumors, hypercortisolism, adrenocorticotropic hormone, ACTH-independent hypercortisolism, ACTH-dependent hypercortisolism, endogenous glucocorticoids, exogenous glucocorticoids, exogenous steroids, moon facies, facial plethora, supraclavicular fat pads, buffalo hump, truncal obesity, purple striae, proximal muscle weakness, easy bruising, hirsutism, growth retardation, HPA-axis suppression, adrenal insufficiency, hypothalamic-pituitary-adrenal axis suppression

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Contributor Information and Disclosures

Author

Gail K Adler, MD, PhD, FAHA, Assistant Professor, Department of Medicine, Division of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital, Harvard Medical School
Gail K Adler, MD, PhD, FAHA is a member of the following medical societies: American Heart Association and Endocrine Society
Disclosure: Nothing to disclose.

Medical Editor

Frederick H Ziel, MD, Associate Professor of Medicine, David Geffen School of Medicine at UCLA; Physician-In-Charge, Endocrinology/Diabetes Center, Director of Medical Education, Kaiser Permanente Woodland Hills; Chair of Endocrinology, Co-Chair of Diabetes Complete Care Program, Southern California Permanente Medical Group
Frederick H Ziel, MD is a member of the following medical societies: American Association of Clinical Endocrinologists, American College of Endocrinology, American College of Physicians, American College of Physicians-American Society of Internal Medicine, American Diabetes Association, American Federation for Medical Research, American Medical Association, American Society for Bone and Mineral Research, California Medical Association, Endocrine Society, and International Society for Clinical Densitometry
Disclosure: Nothing to disclose.

Pharmacy Editor

Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine
Disclosure: eMedicine Salary Employment

Managing Editor

Don S Schalch, MD, Professor Emeritus, Department of Internal Medicine, Division of Endocrinology, University of Wisconsin Hospitals and Clinics
Don S Schalch, MD is a member of the following medical societies: American Diabetes Association, American Federation for Medical Research, Central Society for Clinical Research, and Endocrine Society
Disclosure: Nothing to disclose.

CME Editor

Mark Cooper, MBBS, PhD, FRACP, Head, Diabetes & Metabolism Division, Baker Heart Research Institute, Professor of Medicine, Monash University
Disclosure: Nothing to disclose.

Chief Editor

George T Griffing, MD, Professor of Medicine, St Louis University School of Medicine
George T Griffing, MD is a member of the following medical societies: American Association for the Advancement of Science, American College of Medical Practice Executives, American College of Physician Executives, American College of Physicians, American Diabetes Association, American Federation for Medical Research, American Heart Association, Central Society for Clinical Research, Endocrine Society, International Society for Clinical Densitometry, and Southern Society for Clinical Investigation
Disclosure: Nothing to disclose.

 
 
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