eMedicine Specialties > Neurology > Pediatric Neurology
Myoclonic Epilepsy Beginning in Infancy or Early Childhood: Follow-up
Updated: Aug 21, 2008
Follow-up
Further Outpatient Care
- Serial EEGs often are required to ensure that patients are responding to treatment and that subclinical seizures are not occurring.
- Typical EEG findings in responsive patients include the disappearance of polyspike and wave activity and other associated epileptiform discharges.
Prognosis
- Prognosis depends on the underlying etiology and the syndrome type.
- Patients with a benign syndrome typically respond well to medication. These patients usually have a good prognosis and often outgrow the epilepsy.
- In symptomatic myoclonic epilepsy syndromes, the prognosis is usually less favorable with regard to seizure control and developmental progress.
More on Myoclonic Epilepsy Beginning in Infancy or Early Childhood |
| Overview: Myoclonic Epilepsy Beginning in Infancy or Early Childhood |
| Differential Diagnoses & Workup: Myoclonic Epilepsy Beginning in Infancy or Early Childhood |
| Treatment & Medication: Myoclonic Epilepsy Beginning in Infancy or Early Childhood |
Follow-up: Myoclonic Epilepsy Beginning in Infancy or Early Childhood |
| References |
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References
Zara F, Gennaro E, Stabile M, Carbone I, Malacarne M, Majello L, et al. Mapping of a locus for a familial autosomal recessive idiopathic myoclonic epilepsy of infancy to chromosome 16p13. Am J Hum Genet. May 2000;66(5):1552-7. [Medline].
Wang PJ, Lee WT, Hwu WL, Young C, Yau KI, Shen YZ. The controversy regarding diagnostic criteria for early myoclonic encephalopathy. Brain Dev. Oct 1998;20(7):530-5. [Medline].
Aicardi J. Myoclonic epilepsies of infancy and childhood. Adv Neurol. 1986;43:11-31. [Medline].
Sheth RD. Electroencephalogram in developmental delay: specific electroclinical syndromes. Semin Pediatr Neurol. Mar 1998;5(1):45-51. [Medline].
Doose H, Lunau H, Castiglione E, Waltz S. Severe idiopathic generalized epilepsy of infancy with generalized tonic-clonic seizures. Neuropediatrics. Oct 1998;29(5):229-38. [Medline].
Wallace SJ. Myoclonus and epilepsy in childhood: a review of treatment with valproate, ethosuximide, lamotrigine and zonisamide. Epilepsy Res. Jan 1998;29(2):147-54. [Medline].
Lombroso CT. Early myoclonic encephalopathy, early infantile epileptic encephalopathy, and benign and severe infantile myoclonic epilepsies: a critical review and personal contributions. J Clin Neurophysiol. Jul 1990;7(3):380-408. [Medline].
Shahwan A, Farrell M, Delanty N. Progressive myoclonic epilepsies: a review of genetic and therapeutic aspects. Lancet Neurol. Apr 2005;4(4):239-48. [Medline].
Further Reading
Keywords
myoclonic epilepsy, myoclonic seizures, astatic myoclonic epilepsy of Doose, benign infantile myoclonic epilepsy, infantile spasms, progressive myoclonic epilepsy, severe infantile myoclonic epilepsy
Follow-up: Myoclonic Epilepsy Beginning in Infancy or Early Childhood