eMedicine Specialties > Neurology > Pediatric Neurology

Neonatal Injuries in Child Abuse: Differential Diagnoses & Workup

Author: Nitin C Patel, MD, MPH, Associate Professor of Clinical Neurology and Child Health, Department of Child Health, Interim Division Chief for Developmental Pediatrics and Child Neurology, Specialist in Pediatrics/Neurology, University of Missouri Hospital and Clinics at Columbia
Coauthor(s): Robin D Davenport, BS, MSN, Pediatric Nurse Practitioner, Department of Pediatric Neurology, University of Missouri Health Care Hospitals and Clinics; Bhagwan I Moorjani, MD, FAAP, FAAN, Consulting Staff, Department of Neuroscience, Director, Department of Neuroscience, Division of Evoked Response Laboratory, Children's National Medical Center
Contributor Information and Disclosures

Updated: Mar 18, 2009

Differential Diagnoses

Blood Dyscrasias and Stroke
Subdural Empyema
Cerebellar Hemorrhage
Subdural Hematoma
Epidural Hematoma
Head Injury
Intracranial Hemorrhage

Other Problems to Be Considered

Accidental trauma (eg, subdural hematoma, especially in children with enlarged extra-axial spaces)
Arteriovenous malformation
Bleeding disorders
Connective tissue disorder (ie, osteogenesis imperfecta)
Infectious subdural effusion
Metabolic disorders, especially glutaric aciduria type 1 (can cause retinal hemorrhages and intracranial lesions)

Workup

Laboratory Studies

Laboratory studies for shaken baby syndrome are nonspecific and are not diagnostic.

  • Leukocytosis is seen in approximately 50% of patients.
  • Serum chemistry findings are usually normal, but they may reveal evidence of acidosis.
  • The cerebrospinal fluid may be bloody, possibly indicating subarachnoid hemorrhage.

Imaging Studies

  • The true nature of the problem is often discovered only after CT is performed and evidence of intracranial pathology is found.
  • The key to diagnosing shaken baby syndrome is neuroimaging.
    • CT scanning of the brain is sufficient to diagnose subdural hemorrhage (see Media file 1), cerebral edema (see Media file 2), and/or subarachnoid hemorrhage. CT is usually the first neuroimaging study obtained in the ED.

      CT scan shows a subdural hematoma.

      CT scan shows a subdural hematoma.

      CT scan shows a subdural hematoma.

      CT scan shows a subdural hematoma.


      CT scan shows cerebral edema with loss of gray ma...

      CT scan shows cerebral edema with loss of gray matter–white matter distinction.

      CT scan shows cerebral edema with loss of gray ma...

      CT scan shows cerebral edema with loss of gray matter–white matter distinction.

    • As a follow-up study, MRI can be used to determine the extent of the neurologic injury (see Media files 3-6). MRI may be helpful for continued management and prognosis.

      T1-weighted MRIs reveal bilateral chronic subdura...

      T1-weighted MRIs reveal bilateral chronic subdural hematomas as well as severe encephalomalacia involving the parietal, occipital, and temporal lobes.

      T1-weighted MRIs reveal bilateral chronic subdura...

      T1-weighted MRIs reveal bilateral chronic subdural hematomas as well as severe encephalomalacia involving the parietal, occipital, and temporal lobes.


      T1-weighted MRIs show chronic bilateral subdural ...

      T1-weighted MRIs show chronic bilateral subdural hematomas.

      T1-weighted MRIs show chronic bilateral subdural ...

      T1-weighted MRIs show chronic bilateral subdural hematomas.


      T2-weighted MRIs show encephalomalacia after shak...

      T2-weighted MRIs show encephalomalacia after shaken baby syndrome.

      T2-weighted MRIs show encephalomalacia after shak...

      T2-weighted MRIs show encephalomalacia after shaken baby syndrome.


      Sagittal MRIs show chronic subdural hematoma.

      Sagittal MRIs show chronic subdural hematoma.

      Sagittal MRIs show chronic subdural hematoma.

      Sagittal MRIs show chronic subdural hematoma.

    • Retinal hemorrhages can be seen as early as 48 hours before any intracranial lesions can be detected on brain CT or MRI.
  • As long as the fontanelle is still open, ultrasonography can be performed to identify an intracranial hemorrhage. However, a negative head sonogram does not rule out intracranial pathology.

Other Tests

  • An ophthalmologic evaluation is extremely important and helpful in diagnosis.
    • A dilated eye examination is preferred. However, in the ED, all patients (regardless of the presenting complaint) should receive retinal examination with a direct ophthalmoscope.
    • Papilledema indicates increased intracranial pressure, and retinal hemorrhage strongly suggests shaken baby syndrome (see Media file 7).

      Funduscopic image shows intraretinal hemorrhages,...

      Funduscopic image shows intraretinal hemorrhages, subhyaloid hemorrhages, localized hemorrhagic choroid detachments, and thin retinal folds.

      Funduscopic image shows intraretinal hemorrhages,...

      Funduscopic image shows intraretinal hemorrhages, subhyaloid hemorrhages, localized hemorrhagic choroid detachments, and thin retinal folds.

  • All patients in whom abuse is suspected must be given a long-bone skeletal survey to check for new or healing fractures, which help in the diagnosis.

More on Neonatal Injuries in Child Abuse

Overview: Neonatal Injuries in Child Abuse
Differential Diagnoses & Workup: Neonatal Injuries in Child Abuse
Treatment & Medication: Neonatal Injuries in Child Abuse
Follow-up: Neonatal Injuries in Child Abuse
Multimedia: Neonatal Injuries in Child Abuse
References

References

  1. Caffey J. Multiple fractures in long bones of infants suffering from chronic subdural hematoma. AJR Am J Roentgenol. 1946;36:163-73.

  2. Kempe CH, Silverman FN, Steele BF, et al. The battered-child syndrome. JAMA. Jul 7 1962;181:17-24. [Medline].

  3. Gilkes MJ, Mann TP. Fundi of battered babies. Lancet. 1967;2:468-9.

  4. Caffey J. On the theory and practice of shaking infants. Its potential residual effects of permanent brain damage and mental retardation. Am J Dis Child. Aug 1972;124(2):161-9. [Medline].

  5. Geddes JF, Hackshaw AK, Vowles GH. Neuropathology of inflicted head injury in children. I. Patterns of brain damage. Brain. Jul 2001;124(Pt 7):1290-8. [Medline].

  6. Geddes JF, Vowles GH, Hackshaw AK, et al. Neuropathology of inflicted head injury in children. II. Microscopic brain injury in infants. Brain. Jul 2001;124(Pt 7):1299-306. [Medline].

  7. HHS. Child Maltreatment 2006. Administration for Children and Families [serial online]. Chapter 3:Accessed September 23, 2008. Available at http://www.acf.hhs.gov/programs/cb/pubs/cm06/chapter3.htm.

  8. Missouri Department of Social Services Children's Division. Child Abuse and Neglect in Missouri: Report for Calendar Year 2006: Research and Evaluation. Available at http://digitalarchive.oclc.org/da/ViewObject.jsp?objid=0000020618&reqid=9295. Accessed November 2007.

  9. Bates B. Abused Moms Are More Likely to Spank Infants. Pediatric News. July 2008;Behavior PediatricsChild Abuse Introductionhttp://www.emedicinehealth.com/Articles/9844-1.asp: 22. Available at www.pediatricnews.com.

  10. Kanter RK. Retinal hemorrhage after cardiopulmonary resuscitation or child abuse. J Pediatr. Mar 1986;108(3):430-2. [Medline].

  11. Ludwig S, Warman M. Shaken baby syndrome: a review of 20 cases. Ann Emerg Med. Feb 1984;13(2):104-7. [Medline].

  12. Wilkinson WS, Han DP, Rappley MD, Owings CL. Retinal hemorrhage predicts neurologic injury in the shaken baby syndrome. Arch Ophthalmol. Oct 1989;107(10):1472-4. [Medline].

  13. Alexander R, Sato Y, Smith W, Bennett T. Incidence of impact trauma with cranial injuries ascribed to shaking. Am J Dis Child. Jun 1990;144(6):724-6. [Medline].

  14. Andreadou E, Yapijakis C, Paraskevas GP, et al. Hereditary neuropathy with liability to pressure palsies: the same molecular defect can result in diverse clinical presentation. J Neurol. Mar 1996;243(3):225-30. [Medline].

  15. Bruce DA, Zimmerman RA. Shaken impact syndrome. Pediatr Ann. Aug 1989;18(8):482-4, 486-9, 492-4. [Medline].

  16. Coody D, Brown M, Montgomery D, et al. Shaken baby syndrome: identification and prevention for nurse practitioners. J Pediatr Health Care. Mar-Apr 1994;8(2):50-6. [Medline].

  17. Donohoe M. Shaken baby syndrome (SBS) and non-accidental injuries (NAI). Vaccine Website. Available at http://www.whale.to/v/sbs.html. Accessed March 18, 2009.

  18. Duhaime AC, Alario AJ, Lewander WJ, et al. Head injury in very young children: mechanisms, injury types, and ophthalmologic findings in 100 hospitalized patients younger than 2 years of age. Pediatrics. Aug 1992;90(2 Pt 1):179-85. [Medline].

  19. Duhaime AC, Gennarelli TA, Thibault LE, et al. The shaken baby syndrome. A clinical, pathological, and biomechanical study. J Neurosurg. Mar 1987;66(3):409-15. [Medline].

  20. Ewigman B, Kivlahan C. Child maltreatment fatalities. Pediatr Ann. Aug 1989;18(8):476-8, 480-1. [Medline].

  21. Geddes JF, Plunkett J. The evidence base for shaken baby syndrome. BMJ. Mar 27 2004;328(7442):719-20. [Medline].

  22. Giardino AP, Christian CW, Giardino ER. A Practical Guide to the Evaluation of Child Physical Abuse and Neglect. Thousand Oaks, Calif: Sage; 1997.

  23. Hahn YS, Raimondi AJ, McLone DG, Yamanouchi Y. Traumatic mechanisms of head injury in child abuse. Childs Brain. 1983;10(4):229-41. [Medline].

  24. Ingrahan FD, Matson DD. Subdural hematoma in infancy. J Pediatr. 1944;24:1-37.

  25. Lancon JA, Haines DE, Parent AD. Anatomy of the shaken baby syndrome. Anat Rec. Feb 1998;253(1):13-8. [Medline].

  26. Manning SC, Casselbrant M, Lammers D. Otolaryngologic manifestations of child abuse. Int J Pediatr Otorhinolaryngol. Sep 1990;20(1):7-16. [Medline].

  27. Singer HS, Kossoff EH, Hartman AL, Crawford TO. Shaken baby syndrome (shaken-impact syndrome). In: Treatment of Pediatric Neurologic Disorders. Taylor & Francis; 2005:329-344.

  28. Spaide RF, Swengel RM, Scharre DW, Mein CE. Shaken baby syndrome. Am Fam Physician. Apr 1990;41(4):1145-52. [Medline].

  29. Truth Foundation. Shaken Baby Syndrome: Questions and Controversies. Truth Foundation. Available at http://www.sbstruth.com/Questions%20and%20controversies.htm.

  30. US Department of Health an Human Services. Administration for Children and Families. Factsheets/Publications. Child Maltreatment Reports. Child Maltreatment 2006: Reports from the States to the National Child Abuse and Neglect Data Systems. Available at http://www.acf.hhs.gov/programs/cb/publications/cmreports.htm.

Further Reading

Keywords

shaken baby syndrome, shaken-baby syndrome, SBS, shaking, neurologic injury in child abuse, battered child syndrome, battered-child syndrome, child abuse, shaken infant, shaking impact syndrome, shaking-impact syndrome, retinal hemorrhage

Contributor Information and Disclosures

Author

Nitin C Patel, MD, MPH, Associate Professor of Clinical Neurology and Child Health, Department of Child Health, Interim Division Chief for Developmental Pediatrics and Child Neurology, Specialist in Pediatrics/Neurology, University of Missouri Hospital and Clinics at Columbia
Nitin C Patel, MD, MPH is a member of the following medical societies: American Academy of Neurology, American Epilepsy Society, American Headache Society, and Child Neurology Society
Disclosure: Nothing to disclose.

Coauthor(s)

Robin D Davenport, BS, MSN, Pediatric Nurse Practitioner, Department of Pediatric Neurology, University of Missouri Health Care Hospitals and Clinics
Disclosure: Nothing to disclose.

Bhagwan I Moorjani, MD, FAAP, FAAN, Consulting Staff, Department of Neuroscience, Director, Department of Neuroscience, Division of Evoked Response Laboratory, Children's National Medical Center
Bhagwan I Moorjani, MD, FAAP, FAAN is a member of the following medical societies: American Academy of Neurology
Disclosure: Nothing to disclose.

Medical Editor

Robert Stanley Rust Jr, MD, MA, Thomas E Worrell Jr Professor of Epileptology and Neurology, Co-Director of FE Dreifuss Child Neurology and Epilepsy Clinics, Director, Child Neurology, University of Virginia; Chair-Elect, Child Neurology Section, American Academy of Neurology
Robert Stanley Rust Jr, MD, MA is a member of the following medical societies: American Academy of Neurology, American Epilepsy Society, American Headache Society, American Neurological Association, Child Neurology Society, International Child Neurology Association, and Society for Pediatric Research
Disclosure: Nothing to disclose.

Pharmacy Editor

Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine
Disclosure: Nothing to disclose.

Managing Editor

Kenneth J Mack, MD, PhD, Senior Associate Consultant, Department of Child and Adolescent Neurology, Mayo Clinic
Kenneth J Mack, MD, PhD is a member of the following medical societies: American Academy of Neurology, Child Neurology Society, Phi Beta Kappa, and Society for Neuroscience
Disclosure: Nothing to disclose.

CME Editor

Matthew J Baker, MD, Consulting Staff, Collier Neurologic Specialists, Naples Community Hospital
Matthew J Baker, MD is a member of the following medical societies: American Academy of Neurology
Disclosure: Nothing to disclose.

Chief Editor

Amy Kao, MD, Assistant Professor, Department of Pediatrics, Division of Pediatric Neurology, Department of Neurology, Oregon Health and Science University; Consulting Staff, Shriners Hospital for Children
Amy Kao, MD is a member of the following medical societies: American Academy of Neurology, American Academy of Pediatrics, American Epilepsy Society, and Child Neurology Society
Disclosure: Nothing to disclose.

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