Neonatal Injuries in Child Abuse Workup
- Author: Nitin C Patel, MD, MPH; Chief Editor: Amy Kao, MD more...
Laboratory Studies
Laboratory studies for shaken baby syndrome are nonspecific and are not diagnostic.
- Leukocytosis is seen in approximately 50% of patients.
- Serum chemistry findings are usually normal, but they may reveal evidence of acidosis.
- The cerebrospinal fluid may be bloody, possibly indicating subarachnoid hemorrhage.
- Obtain urine for organic acids to rule out a diagnosis of glutaric acidemia.
Imaging Studies
- The true nature of the problem is often discovered only after CT is performed and evidence of intracranial pathology is found.
- The key to diagnosing shaken baby syndrome is neuroimaging.
- CT scanning of the brain is sufficient to diagnose subdural hemorrhage (see the first image below), cerebral edema (see the second image below), and/or subarachnoid hemorrhage. CT is usually the first neuroimaging study obtained in the ED.
CT scan shows a subdural hematoma.
CT scan shows cerebral edema with loss of gray matter–white matter distinction. - As a follow-up study, MRI can be used to determine the extent of the neurologic injury (see the images below). MRI may be helpful for continued management and prognosis.
T1-weighted MRIs reveal bilateral chronic subdural hematomas as well as severe encephalomalacia involving the parietal, occipital, and temporal lobes.
T1-weighted MRIs show chronic bilateral subdural hematomas.
T2-weighted MRIs show encephalomalacia after shaken baby syndrome.
Sagittal MRIs show chronic subdural hematoma. - Retinal hemorrhages can be seen as early as 48 hours before any intracranial lesions can be detected on brain CT or MRI.
- CT scanning of the brain is sufficient to diagnose subdural hemorrhage (see the first image below), cerebral edema (see the second image below), and/or subarachnoid hemorrhage. CT is usually the first neuroimaging study obtained in the ED.
- As long as the fontanelle is still open, ultrasonography can be performed to identify an intracranial hemorrhage. However, a negative head sonogram does not rule out intracranial pathology.
Other Tests
- An ophthalmologic evaluation is extremely important and helpful in diagnosis.
- A dilated eye examination is preferred. However, in the ED, all patients (regardless of the presenting complaint) should receive retinal examination with a direct ophthalmoscope.
- Papilledema indicates increased intracranial pressure, and retinal hemorrhage strongly suggests shaken baby syndrome (see the image below).
Funduscopic image shows intraretinal hemorrhages, subhyaloid hemorrhages, localized hemorrhagic choroid detachments, and thin retinal folds.
- All patients in whom abuse is suspected must be given a long-bone skeletal survey to check for new or healing fractures, which help in the diagnosis.
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