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Vein of Galen Malformation Differential Diagnoses

  • Author: Raj D Sheth, MD; Chief Editor: Amy Kao, MD  more...
 
Updated: Nov 18, 2015
 
 
 
Contributor Information and Disclosures
Author

Raj D Sheth, MD Chief, Division of Pediatric Neurology, Nemours Children's Clinic; Professor of Neurology, Mayo College of Medicine; Professor of Pediatrics, University of Florida College of Medicine

Raj D Sheth, MD is a member of the following medical societies: American Academy of Neurology, American Academy of Pediatrics, American Epilepsy Society, American Neurological Association, Child Neurology Society

Disclosure: Nothing to disclose.

Specialty Editor Board

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

Kenneth J Mack, MD, PhD Senior Associate Consultant, Department of Child and Adolescent Neurology, Mayo Clinic

Kenneth J Mack, MD, PhD is a member of the following medical societies: American Academy of Neurology, Child Neurology Society, Phi Beta Kappa, Society for Neuroscience

Disclosure: Nothing to disclose.

Chief Editor

Amy Kao, MD Attending Neurologist, Children's National Medical Center

Amy Kao, MD is a member of the following medical societies: American Academy of Neurology, American Epilepsy Society, Child Neurology Society

Disclosure: Have stock from Cellectar Biosciences; have stock from Varian medical systems; have stock from Express Scripts.

Additional Contributors

Ann M Neumeyer, MD Medical Director, Lurie Center for Autism; Assistant Professor of Neurology, Harvard Medical School; Child Neurologist, Massachusetts General Hospital

Ann M Neumeyer, MD is a member of the following medical societies: American Academy of Neurology, Child Neurology Society, Massachusetts Medical Society

Disclosure: Nothing to disclose.

Acknowledgements

The authors and editors of Medscape Reference gratefully acknowledge the contributions of previous author, Ernesto Tiznado-Garcia, MD, to the development and writing of this article.

References
  1. Golombek SG, Ally S, Woolf PK. A newborn with cardiac failure secondary to a large vein of Galen malformation. South Med J. 2004 May. 97(5):516-8. [Medline].

  2. Incorpora G, Pavone P, Platania N, Trifiletti RR, Parano E. Vein of Galen malformation and infantile spasms. J Child Neurol. 1999 Mar. 14(3):196-8. [Medline].

  3. Revencu N, Boon LM, Mulliken JB, et al. Parkes Weber syndrome, vein of Galen aneurysmal malformation, and other fast-flow vascular anomalies are caused by RASA1 mutations. Hum Mutat. 2008 Jul. 29(7):959-65. [Medline].

  4. Deloison B, Chalouhi GE, Sonigo P, Zerah M, Millischer AE, Dumez Y, et al. Hidden mortality of prenatally diagnosed vein of Galen aneurysmal malformation: retrospective study and review of the literature. Ultrasound Obstet Gynecol. 2012 Dec. 40 (6):652-8. [Medline].

  5. Jagadeesan BD, Cross DT 3rd, Delgado Almandoz JE, et al. Susceptibility-Weighted Imaging: A New Tool in the Diagnosis and Evaluation of Abnormalities of the Vein of Galen in Children. AJNR Am J Neuroradiol. 2012 Apr 19. [Medline].

  6. Gladstone DJ, Silver FL, Willinsky RA, Tyndel FJ, Wennberg R. Deep cerebral venous thrombosis: an illustrative case with reversible diencephalic dysfunction. Can J Neurol Sci. 2001 May. 28(2):159-62. [Medline].

  7. Jee RC, Lin SH. Teaching NeuroImages: Reversible bilateral thalamic lesions in vein of Galen thrombosis. Neurology. 2009 Sep 22. 73(12):e57. [Medline].

  8. Yan J, Wen J, Gopaul R, Zhang CY, Xiao SW. Outcome and complications of endovascular embolization for vein of Galen malformations: a systematic review and meta-analysis. J Neurosurg. 2015 Oct. 123 (4):872-90. [Medline].

  9. Hoang S, Choudhri O, Edwards M, Guzman R. Vein of Galen malformation. Neurosurg Focus. 2009 Nov. 27(5):E8. [Medline].

  10. Lasjaunias PL, Chng SM, Sachet M, Alvarez H, Rodesch G, Garcia-Monaco R. The management of vein of Galen aneurysmal malformations. Neurosurgery. 2006 Nov. 59(5 Suppl 3):S184-94; discussion S3-13. [Medline].

  11. Lylyk P, Vinuela F, Dion JE, et al. Therapeutic alternatives for vein of Galen vascular malformations. J Neurosurg. 1993 Mar. 78(3):438-45. [Medline].

  12. Moriarity JL Jr, Steinberg GK. Surgical obliteration for vein of Galen malformation: a case report. Surg Neurol. 1995 Oct. 44(4):365-9; discussion 369-70. [Medline].

  13. Iizuka Y, Kakihara T, Suzuki M, Komura S, Azusawa H. Endovascular remodeling technique for vein of Galen aneurysmal malformations--angiographic confirmation of a connection between the median prosencephalic vein and the deep venous system. J Neurosurg Pediatrics. 2008 Jan. 1(1):75-8. [Medline].

  14. Feletti A, Denaro L, Marton E, d'Avella D, Longatti P. Endoscopic treatment of hydrocephalus due to aneurysm of the vein of Galen: case report and literature review. Minim Invasive Neurosurg. 2007 Oct. 50(5):285-91. [Medline].

  15. Abend NS, Ichord R, Aijun Zhang, Hurst R. Vein of galen aneurysmal malformation with deep venous communication and subarachnoid hemorrhage. J Child Neurol. 2008 Apr. 23(4):441-6. [Medline].

  16. Geibprasert S, Krings T, Armstrong D, Terbrugge KG, Raybaud CA. Predicting factors for the follow-up outcome and management decisions in vein of Galen aneurysmal malformations. Childs Nerv Syst. 2010 Jan. 26(1):35-46. [Medline].

  17. de Koning TJ, Gooskens R, Veenhoven R, et al. Arteriovenous malformation of the vein of Galen in three neonates: emphasis on associated early ischaemic brain damage. Eur J Pediatr. 1997 Mar. 156(3):228-9. [Medline].

  18. Porzionato A, Macchi V, Parenti A, De Caro R. Vein of Galen aneurysm: anatomical study of an adult autopsy case. Clin Anat. 2004 Sep. 17(6):458-62. [Medline].

  19. Squires LA, Thomas S, Betz BW, Cottingham S. Vein of Galen malformation with diencephalic syndrome: a clinical pathologic report. J Child Neurol. 1998 Nov. 13(11):575-7. [Medline].

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Cerebral MRI showing large flow void in the central region with enlarged straight sinus.
Coronal MRI of head showing large central vein of Galen malformation with moderate degree of hydrocephalus.
Cranial MRI showing flow void in the sagittal plain and drainage to the straight and transverse sinuses.
Sagittal cerebral MRI with gadolinium showing the relationship of a vein of Galen malformation to the corpus callosum.
MRI venogram showing vein of Galen malformation with draining veins.
Venogram showing the draining vasculature for the vein of Galen malformation.
Skull radiograph showing coils that have been placed during an intravascular embolization of a vein of Galen malformation. Note the ventriculoperitoneal shunt catheter in the anterior head region to relieve hydrocephalus.
 
 
 
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