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Postoperative Corneal Melt Differential Diagnoses

  • Author: Arun Verma, MD; Chief Editor: Hampton Roy, Sr, MD  more...
 
Updated: Dec 01, 2015
 
 
 
Contributor Information and Disclosures
Author

Arun Verma, MD Senior Consultant, Department of Ophthalmology, Dr Daljit Singh Eye Hospital, India

Disclosure: Nothing to disclose.

Specialty Editor Board

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

Christopher J Rapuano, MD Professor, Department of Ophthalmology, Jefferson Medical College of Thomas Jefferson University; Director of the Cornea Service, Co-Director of Refractive Surgery Department, Wills Eye Hospital

Christopher J Rapuano, MD is a member of the following medical societies: American Academy of Ophthalmology, American Ophthalmological Society, American Society of Cataract and Refractive Surgery, Contact Lens Association of Ophthalmologists, International Society of Refractive Surgery, Cornea Society, Eye Bank Association of America

Disclosure: Serve(d) as a director, officer, partner, employee, advisor, consultant or trustee for: Cornea Society, Allergan, Bausch & Lomb, Bio-Tissue, Shire, TearScience, TearLab<br/>Serve(d) as a speaker or a member of a speakers bureau for: Allergan, Bausch & Lomb, Bio-Tissue, TearScience.

Chief Editor

Hampton Roy, Sr, MD Associate Clinical Professor, Department of Ophthalmology, University of Arkansas for Medical Sciences

Hampton Roy, Sr, MD is a member of the following medical societies: American Academy of Ophthalmology, American College of Surgeons, Pan-American Association of Ophthalmology

Disclosure: Nothing to disclose.

Additional Contributors

Richard W Allinson, MD Associate Professor, Department of Ophthalmology, Texas A&M University Health Science Center; Senior Staff Ophthalmologist, Scott and White Clinic

Richard W Allinson, MD is a member of the following medical societies: American Academy of Ophthalmology, American Medical Association, Texas Medical Association

Disclosure: Nothing to disclose.

References
  1. Cottinger, AJ, Berkley, RP, Nordan IT, et al. Bacterial corneal ulcers following keratorefractive surgery. A retrospective study of 14163 procedures. Paper presented at: Ocular Microbiology Immunology Group Meeting. San Francisco, CA; September 28, 1985.

  2. Kymionis GD, Kankariya VP, Kontadakis GA. Combined treatment with flap amputation, phototherapeutic keratectomy, and collagen crosslinking in severe intractable post-LASIK atypical mycobacterial infection with corneal melt. J Cataract Refract Surg. 2012 Apr. 38(4):713-5. [Medline].

  3. Greiner MA, Li JY, Mannis MJ. Longer-term vision outcomes and complications with the Boston type 1 keratoprosthesis at the University of California, Davis. Ophthalmology. 2011 Aug. 118(8):1543-50. [Medline].

  4. Sivaraman KR, Hou JH, Allemann N, de la Cruz J, Cortina MS. Retroprosthetic membrane and risk of sterile keratolysis in patients with type I Boston Keratoprosthesis. Am J Ophthalmol. 2013 May. 155(5):814-22. [Medline].

  5. Praidou A, Brazitikos P, Dastiridou A, Androudi S. Severe unilateral corneal melting after uneventful phacoemulsification cataract surgery. Clin Exp Optom. 2013 Jan. 96(1):109-11. [Medline].

  6. Yang HK, Kline OR Jr. Corneal melting with intraocular lenses. Arch Ophthalmol. 1982 Aug. 100(8):1272-4. [Medline].

  7. Gelender H. Descemetocele after intraocular lens implantation. Arch Ophthalmol. 1982 Jan. 100(1):72-6. [Medline].

  8. Insler MS, Boutros G, Boulware DW. Corneal ulceration following cataract surgery in patients with rheumatoid arthritis. J Am Intraocul Implant Soc. 1985 Nov. 11(6):594-7. [Medline].

  9. Utine CA, Tzu JH, Akpek EK. Lamellar keratoplasty using gamma-irradiated corneal lenticules. Am J Ophthalmol. 2011 Jan. 151(1):170-174.e1. [Medline].

  10. Barletta JP, Angella G, Balch KC, Dimova HG, Stern GA, Moser MT, et al. Inhibition of pseudomonal ulceration in rabbit corneas by a synthetic matrix metalloproteinase inhibitor. Invest Ophthalmol Vis Sci. 1996 Jan. 37(1):20-8. [Medline].

  11. Barletta JP, Balch KC, Dimova, et al. Inhibition of Pseudomonas corneal ulcers by a synthetic matrix metalloprotease inhibitor Galardin (GM[6001]). Invest Ophthalmol Vis Sci. 1993. 34:1058.

  12. Benson WE, Diamond JG, Tasman W. Intraocular irrigating solutions for pars plana vitrectomy. A prospective, randomized, double-blind study. Arch Ophthalmol. 1981 Jun. 99(6):1013-5. [Medline].

  13. Bernauer W, Ficker LA, Watson PG, Dart JK. The management of corneal perforations associated with rheumatoid arthritis. An analysis of 32 eyes. Ophthalmology. 1995 Sep. 102(9):1325-37. [Medline].

  14. Binder PS, Baumgartner SD, Fogle JA. Histopathology of a case of epikeratophakia (aphakic epikeratoplasty). Arch Ophthalmol. 1985 Sep. 103(9):1357-63. [Medline].

  15. Binder PS, Zavala EY. Why do some epikeratoplasties fail?. Arch Ophthalmol. 1987 Jan. 105(1):63-9. [Medline].

  16. Cameron ME. Preventable complications of pterygium excision with beta-irradiation. Br J Ophthalmol. 1972 Jan. 56(1):52-6. [Medline].

  17. Castillo A, Diaz-Valle D, Gutierrez AR, Toledano N, Romero F. Peripheral melt of flap after laser in situ keratomileusis. J Refract Surg. 1998 Jan-Feb. 14(1):61-3. [Medline].

  18. Chung H, Tolentino FI, Cajita VN, Acosta J, Refojo MF. Reevaluation of corneal complications after closed vitrectomy. Arch Ophthalmol. 1988 Jul. 106(7):916-9. [Medline].

  19. Clewes AR, Tunn EJ, Kaye S, Bucknall RC. Use of intravenous cyclophosphamide in the prevention of corneal melt: justified or not?. Rheumatology (Oxford). 2005 Feb. 44(2):257-8. [Medline].

  20. Dougherty PJ, Hardten DR, Lindstrom RL. Corneoscleral melt after pterygium surgery using a single intraoperative application of mitomycin-C. Cornea. 1996 Sep. 15(5):537-40. [Medline].

  21. Dua HS, Saini JS, Azuara-Blanco A, Gupta P. Limbal stem cell deficiency: concept, aetiology, clinical presentation, diagnosis and management. Indian J Ophthalmol. 2000 Jun. 48(2):83-92. [Medline].

  22. Edelhauser HF, Hine JE, Pederson H, Van Horn DL, Schultz RO. The effect of phenylephrine on the cornea. Arch Ophthalmol. 1979 May. 97(5):937-47. [Medline].

  23. Ewing-Chow DA, Romanchuk KG, Gilmour GR, Underhill JH, Climenhaga DB. Corneal melting after pterygium removal followed by topical mitomycin C therapy. Can J Ophthalmol. 1992 Jun. 27(4):197-9. [Medline].

  24. Farrell PL, Smith RE. Bacterial corneoscleritis complicating pterygium excision. Am J Ophthalmol. 1989 May 15. 107(5):515-7. [Medline].

  25. Foulks GN, Thoft RA, Perry HD, Tolentino FI. Factors related to corneal epithelial complications after closed vitrectomy in diabetics. Arch Ophthalmol. 1979 Jun. 97(6):1076-8. [Medline].

  26. Gelender H. Corneal melting syndrome. Arch Ophthalmol. 1983 Feb. 101(2):303. [Medline].

  27. Gilliland GD, Hutton WL, Fuller DG. Retained intravitreal lens fragments after cataract surgery. Ophthalmology. 1992 Aug. 99(8):1263-7; discussion 1268-9. [Medline].

  28. Grayson, M. Diseases of the Cornea. 2nd ed. St Louis: CV Mosby; 1983.

  29. Gupta S, Basti S. Corneoscleral, ciliary body, and vitreoretinal toxicity after excessive instillation of mitomycin C. Am J Ophthalmol. 1992 Oct 15. 114(4):503-4. [Medline].

  30. Hoffer KJ, Darin JJ, Pettit TH, Hofbauer JD, Elander R, Levenson JE. Three years experience with radial keratotomy. The UCLA study. Ophthalmology. 1983 Jun. 90(6):627-36. [Medline].

  31. Hong C, Kitazawa Y, Tanishima T. Influence of argon laser treatment of glaucoma on corneal endothelium. Jpn J Ophthalmol. 1983. 27(4):567-74. [Medline].

  32. Lam DS, Leung AT, Wu JT, Fan DS, Cheng AC, Wang Z. Culture-negative ulcerative keratitis after laser in situ keratomileusis. J Cataract Refract Surg. 1999 Jul. 25(7):1004-8. [Medline].

  33. Latina MA, Melamed S, March WF, Kass MA, Kolker AE. Gonioscopic ab interno laser sclerostomy. A pilot study in glaucoma patients. Ophthalmology. 1992 Nov. 99(11):1736-44. [Medline].

  34. Leahey AB, Gottsch JD, Stark WJ. Clinical experience with N-butyl cyanoacrylate (Nexacryl) tissue adhesive. Ophthalmology. 1993 Feb. 100(2):173-80. [Medline].

  35. Lemp MA. Cornea and sclera. Arch Ophthalmol. 1974 Aug. 92(2):158-70. [Medline].

  36. Liu SM, Su J, Hemady RK. Corneal melting after avulsion of a Molteno shunt plate. J Glaucoma. 1997 Dec. 6(6):357-8. [Medline].

  37. Mamalis N, Johnson MD, Haines JM, Teske MP, Olson RJ. Corneal-scleral melt in association with cataract surgery and intraocular lenses: a report of four cases. J Cataract Refract Surg. 1990 Jan. 16(1):108-15. [Medline].

  38. Mandelbaum S, Waring GO 3rd, Forster RK, Culbertson WW, Rowsey JJ, Espinal ME. Late development of ulcerative keratitis in radial keratotomy scars. Arch Ophthalmol. 1986 Aug. 104(8):1156-60. [Medline].

  39. Margherio RR, Cox MS Jr, Trese MT, Murphy PL, Johnson J, Minor LA. Removal of epimacular membranes. Ophthalmology. 1985 Aug. 92(8):1075-83. [Medline].

  40. Margo CE, Polack FM, Hood CI. Aspergillus panophthalmitis complicating treatment of pterygium. Cornea. 1988. 7(4):285-9. [Medline].

  41. Morgan KS, Asbell PA, McDonald MB, May JG, Loupe DN, Kaufman HE. Preliminary visual results of pediatric epikeratophakia. Arch Ophthalmol. 1983 Oct. 101(10):1540-4. [Medline].

  42. Nelson JD, Williams P, Lindstrom RL, Doughman DJ. Map-fingerprint-dot changes in the corneal epithelial basement membrane following radial keratotomy. Ophthalmology. 1985 Feb. 92(2):199-205. [Medline].

  43. Ohashi Y, Matsuda M, Hosotani H, Tano Y, Ishimoto I, Fukuda M, et al. Aldose reductase inhibitor (CT-112) eyedrops for diabetic corneal epitheliopathy. Am J Ophthalmol. 1988 Mar 15. 105(3):233-8. [Medline].

  44. Pflugfelder SC, Saulson R, Ullman S. Peripheral corneal ulceration in a patient with AIDS-related complex. Am J Ophthalmol. 1987 Nov 15. 104(5):542-3. [Medline].

  45. Portnoy SL, Insler MS, Kaufman HE. Surgical management of corneal ulceration and perforation. Surv Ophthalmol. 1989 Jul-Aug. 34(1):47-58. [Medline].

  46. Pérez-Santonja JJ, Bellot J, Claramonte P, Ismail MM, Alió JL. Laser in situ keratomileusis to correct high myopia. J Cataract Refract Surg. 1997 Apr. 23(3):372-85. [Medline].

  47. Quillen DA, Rosenwasser GO. Aerosol application of cyanoacrylate adhesive. J Refract Corneal Surg. 1994 Mar-Apr. 10(2):149-50. [Medline].

  48. Refojo MF, Dohlman CH, Ahmad B, Carroll JM, Allen JC. Evaluation of adhesives for corneal surgery. Arch Ophthalmol. 1968 Nov. 80(5):645-56. [Medline].

  49. Rosenbery S. Corneal dellen following contact-lens wear. Am J Ophthalmol. 1969 Jun. 67(6):970. [Medline].

  50. Roy FH. Ocular Differential Diagnosis. 4th ed. Philadelphia: Lea and Febiger; 1984.

  51. Rubinfeld RS, Pfister RR, Stein RM, Foster CS, Martin NF, Stoleru S, et al. Serious complications of topical mitomycin-C after pterygium surgery. Ophthalmology. 1992 Nov. 99(11):1647-54. [Medline].

  52. Schwartz DE. Corneal sensitivity in diabetics. Arch Ophthalmol. 1974 Mar. 91(3):174-8. [Medline].

  53. Shivitz IA, Arrowsmith PN. Delayed keratitis after radial keratotomy. Arch Ophthalmol. 1986 Aug. 104(8):1153-5. [Medline].

  54. Smith RE, Schanzlin DJ. Rheumatoid diseases. Smolin, Thoft, eds. The Cornea: Scientific Foundations and Clinical Practice. 2nd ed. Boston: Little, Brown & Co; 1997.

  55. Smith SG, Lindstrom RL, Nelson JD, Weiss JL, Doughman DJ. Corneal ulcer-infiltrate associated with soft contact lens use following penetrating keratoplasty. Cornea. 1984. 3(2):131-4. [Medline].

  56. Soong HK, Quigley HA. Dellen associated with filtering blebs. Arch Ophthalmol. 1983 Mar. 101(3):385-7. [Medline].

  57. Stern GA, Weitzenkorn D, Valenti J. Adherence of Pseudomonas aeruginosa to the mouse cornea. Epithelial v stromal adherence. Arch Ophthalmol. 1982 Dec. 100(12):1956-8. [Medline].

  58. Swinger CA, Villasenor RA. Homoplastic keratomileusis for correction of myopia. J Refr Surg. 1985. 1:219-23.

  59. Townsend WM. Corneal melt after cataract surgery. Conjunctival flaps. The Cornea. New York: Churchill Livingstone; 1988. 669.

  60. Vitrectomy with silicone oil or perfluoropropane gas in eyes with severe proliferative vitreoretinopathy: results of a randomized clinical trial. Silicone Study Report 2. Arch Ophthalmol. 1992 Jun. 110(6):780-92. [Medline].

  61. Vitrectomy with silicone oil or sulfur hexafluoride gas in eyes with severe proliferative vitreoretinopathy: results of a randomized clinical trial. Silicone Study Report 1. Arch Ophthalmol. 1992 Jun. 110(6):770-9. [Medline].

  62. Waring GO 3rd, Lynn MJ, Gelender H, Laibson PR, Lindstrom RL, Myers WD, et al. Results of the prospective evaluation of radial keratotomy (PERK) study one year after surgery. Ophthalmology. 1985 Feb. 92(2):177-98, 307. [Medline].

  63. Weiss JL, Williams P, Lindstrom RL, Doughman DJ. The use of tissue adhesive in corneal perforations. Ophthalmology. 1983 Jun. 90(6):610-5. [Medline].

  64. Wilhelmus KR. Corneal edema following argon laser iridotomy. Ophthalmic Surg. 1992 Aug. 23(8):533-7. [Medline].

  65. Wilhelmus KR, Hamburg S. Bacterial keratitis following radial keratotomy. Cornea. 1983. 2:143-6.

  66. Zabel RW, MacDonald IM, Mintsioulis G. Corneal endothelial decompensation after argon laser iridotomy. Can J Ophthalmol. 1991 Dec. 26(7):367-73. [Medline].

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