eMedicine Specialties > Ophthalmology > Cornea
Dystrophy, Granular: Differential Diagnoses & Workup
Updated: Mar 15, 2006
- Overview
- Differential Diagnoses & Workup
- Treatment & Medication
- Follow-up
- Multimedia
Differential Diagnoses
Dystrophy, Crystalline
Dystrophy, Lattice
Dystrophy, Macular
Dystrophy, Map-dot-fingerprint
Other Problems to Be Considered
Corneal opacities
Workup
Other Tests
- Corneal biopsy (which would never be indicated clinically) would reveal eosinophilic hyaline deposits in corneal stroma. When a corneal transplant is performed, the specimen is submitted for histopathologic evaluation
- Masson trichrome stains deposits bright red.
Histologic Findings
When corneal specimens are obtained, light microscopy reveals eosinophilic hyaline deposits in the corneal stroma; the source of hyaline material is still unknown. Masson trichrome stains the deposits bright red.
More on Dystrophy, Granular |
| Overview: Dystrophy, Granular |
Differential Diagnoses & Workup: Dystrophy, Granular |
| Treatment & Medication: Dystrophy, Granular |
| Follow-up: Dystrophy, Granular |
| Multimedia: Dystrophy, Granular |
| References |
| « Previous Page | Next Page » |
References
Albert D, Jakobiec F. Principles and Practice of Ophthalmology. Vol 1. 1994:26-49.
Das S, Langenbucher A, Seitz B. Excimer laser phototherapeutic keratectomy for granular and lattice corneal dystrophy: a comparative study. J Refract Surg. Nov-Dec 2005;21(6):727-31. [Medline].
Grunauer-Kloevekorn C, Brautigam S, Wolter-Roessler M. Molecular genetic analysis of the BIGH3 gene in lattice type I (Biber-Haab-Dimmer) and granular type II (Avellino) corneal dystrophy: is indirect mutation analysis for hot spots recommended?. Klin Monatsbl Augenheilkd. Dec 2005;222(12):1017-23. [Medline].
Klintworth GK. Advances in the molecular genetics of corneal dystrophies. Am J Ophthalmol. Dec 1999;128(6):747-54. [Medline].
Krachmer J. Cornea. Vol 2. 1996.
Yamamoto S, Okada M, Tsujikawa M, et al. The spectrum of beta ig-h3 gene mutations in Japanese patients with corneal dystrophy. Cornea. May 2000;19(3 Suppl):S21-3. [Medline].
Further Reading
Keywords
granular dystrophy, corneal dystrophy, granular corneal dystrophy
Differential Diagnoses & Workup: Dystrophy, Granular