Lattice Corneal Dystrophy Treatment & Management
- Author: Natalie A Afshari, MD, MA, FACS; Chief Editor: Hampton Roy, Sr, MD more...
When recurrent erosions occur with lattice corneal dystrophy, they are treated similarly to any other form of recurrent erosions. Under the care of an ophthalmologist, a bandage contact lens along with antibiotics can be prescribed. Alternatively, patching with an antibiotic ointment can be used. Once the acute episode of recurrent erosions has resolved, preventative treatments may include Muro 128 drops, lubrication drops, and lubricating ointment at bedtime. If recurrent corneal erosions occur despite medical therapy, excimer laser phototherapeutic keratectomy (PTK) may be considered.[7, 8]
Excessive corneal erosions or mild visual decreases can be treated with laser phototherapeutic keratectomy (PTK). The excimer laser removes any opacities, smooths the corneal surface, and allows the epithelium to re-adhere more tightly. If visual acuity worsens and opacities are deep, a lamellar or full-thickness corneal transplant can be performed. Corneal transplants are usually not necessary until after age 40 years. Although the success rate for a corneal transplant is very high, amyloid deposits can recur in the grafted tissue 2-14 years later.
A recent study examined the histopathological and ultrastructural correlate of delayed epithelial healing in eyes with lattice corneal dystrophy; the study concluded that histopathological findings may correspond to reduced cell matrix interactions and may help explain the delayed healing.
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