eMedicine Specialties > Ophthalmology > Cornea
Dystrophy, Map-dot-fingerprint: Differential Diagnoses & Workup
Updated: May 26, 2009
- Overview
- Differential Diagnoses & Workup
- Treatment & Medication
- Follow-up
- Multimedia
Differential Diagnoses
Corneal Abrasion
Dystrophy, Fuchs Endothelial
Herpes Simplex
Herpes Zoster
Other Problems to Be Considered
Corneal trauma
Diabetes mellitus (can be thickened and redundant basement membrane)
Corneal suture lines (junction of a healing corneal epithelial defect)
Radial keratotomy (can have corneal epithelial opacities clinically indistinguishable from map-dot-fingerprint dystrophy)
Workup
Histologic Findings
The corneal maps in map-dot-fingerprint dystrophy histologically represent areas of multilaminar basement membrane, which extend into the epithelium. The corneal dots in map-dot-fingerprint dystrophy are intraepithelial microcysts that contain nuclear, cytoplasmic, and lipid debris. The corneal fingerprints in map-dot-fingerprint dystrophy are curvilinear clusters of reduplicated and thickened basement membrane and fibrillogranular material.
Blebs, a less common manifestation of map-dot-fingerprint dystrophy, are localized areas of fibrillogranular material or thickened basement membrane.
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| Overview: Dystrophy, Map-dot-fingerprint |
Differential Diagnoses & Workup: Dystrophy, Map-dot-fingerprint |
| Treatment & Medication: Dystrophy, Map-dot-fingerprint |
| Follow-up: Dystrophy, Map-dot-fingerprint |
| Multimedia: Dystrophy, Map-dot-fingerprint |
| References |
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References
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Further Reading
Keywords
map-dot-fingerprint dystrophy, corneal map-dot-fingerprint dystrophy, Cogan’s dystrophy, Cogan's microcystic dystrophy, anterior basement membrane dystrophy, epithelial basement membrane dystrophy, corneal dystrophy, corneal dystrophies, corneal degeneration, corneal erosion
Differential Diagnoses & Workup: Dystrophy, Map-dot-fingerprint