Map-dot-fingerprint Dystrophy Workup

  • Author: David Verdier, MD; Chief Editor: Hampton Roy Sr, MD   more...
 
Updated: Feb 14, 2012
 

Histologic Findings

The corneal maps in map-dot-fingerprint dystrophy histologically represent areas of multilaminar basement membrane, which extend into the epithelium. The corneal dots in map-dot-fingerprint dystrophy are intraepithelial microcysts that contain nuclear, cytoplasmic, and lipid debris. The corneal fingerprints in map-dot-fingerprint dystrophy are curvilinear clusters of reduplicated and thickened basement membrane and fibrillogranular material.

Blebs, a less common manifestation of map-dot-fingerprint dystrophy, are localized areas of fibrillogranular material or thickened basement membrane.

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Contributor Information and Disclosures
Author

David Verdier, MD  Clinical Professor, Department of Surgery, Division of Ophthalmology, Michigan State University College of Human Medicine

David Verdier, MD is a member of the following medical societies: American Academy of Ophthalmology, American Medical Association, Cornea Society, Eye Bank Association of America, Michigan Society of Eye Physicians & Surgeons, and Michigan State Medical Society

Disclosure: Nothing to disclose.

Specialty Editor Board

Fernando H Murillo-Lopez, MD  Senior Surgeon, Unidad Privada de Oftalmologia CEMES

Fernando H Murillo-Lopez, MD is a member of the following medical societies: American Academy of Ophthalmology

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD  Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Medscape Salary Employment

Christopher J Rapuano, MD  Professor, Department of Ophthalmology, Jefferson Medical College of Thomas Jefferson University; Director of the Cornea Service, Co-Director of Refractive Surgery Department, Wills Eye Institute

Christopher J Rapuano, MD is a member of the following medical societies: American Academy of Ophthalmology, American Society of Cataract and Refractive Surgery, Contact Lens Association of Ophthalmologists, Cornea Society, Eye Bank Association of America, International Society of Refractive Surgery, and Pan-American Association of Ophthalmology

Disclosure: Allergan Honoraria Speaking and teaching; Allergan Consulting fee Consulting; Alcon Honoraria Speaking and teaching; RPS Ownership interest Other; EyeGate Pharma Consulting fee Consulting; Bausch & Lomb Honoraria Speaking and teaching; Bausch & Lomb Consulting; Merck Honoraria Speaking and teaching

Lance L Brown, OD, MD  Ophthalmologist, Affiliated With Freeman Hospital and St John's Hospital, Regional Eye Center, Joplin, Missouri

Disclosure: Nothing to disclose.

Chief Editor

Hampton Roy Sr, MD  Associate Clinical Professor, Department of Ophthalmology, University of Arkansas for Medical Sciences

Hampton Roy Sr, MD is a member of the following medical societies: American Academy of Ophthalmology, American College of Surgeons, and Pan-American Association of Ophthalmology

Disclosure: Nothing to disclose.

References

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Corneal maps. Best seen with broad illumination beam.
Corneal dots. Cluster of corneal dots.
Corneal fingerprints. Best seen in retroillumination.
Pseudofingerprints (shift lines) in a patient with Fuchs corneal dystrophy.
 
 
 
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