eMedicine Specialties > Ophthalmology > Cornea
Herpes Simplex: Differential Diagnoses & Workup
Updated: Feb 20, 2009
- Overview
- Differential Diagnoses & Workup
- Treatment & Medication
- Follow-up
Differential Diagnoses
Other Problems to Be Considered
Impetigo
Tyrosinemia
Acanthamoeba keratitis
Staphylococcus marginal ulcer
Cogan syndrome
Measles and mumps
Neurotrophic keratitis
Workup
Laboratory Studies
- The diagnosis is usually clinical, based on the presence of lid lesions or a characteristic dendrite.
- If the diagnosis is in doubt, laboratory diagnosis can be made using the following:
- Giemsa stain
- Papanicolaou stain
- Viral culture
- Immunohistochemistry looking for viral antigens
- Polymerase chain reaction (PCR)
Histologic Findings
Giemsa stain of scrapings of the corneal or skin lesions shows multinucleated giant cells. Papanicolaou stain shows intranuclear eosinophilic inclusion bodies.
More on Herpes Simplex |
| Overview: Herpes Simplex |
Differential Diagnoses & Workup: Herpes Simplex |
| Treatment & Medication: Herpes Simplex |
| Follow-up: Herpes Simplex |
| References |
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References
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Further Reading
Keywords
herpes simplex, herpes simplex virus, HSV, keratitis, corneal ulcer, dendrite, conjunctivitis
Differential Diagnoses & Workup: Herpes Simplex