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Pellucid Marginal Degeneration Differential Diagnoses

  • Author: Karim Rasheed, MD, MSc; Chief Editor: Hampton Roy, Sr, MD  more...
 
Updated: Sep 08, 2014
 
 

Differential Diagnoses

 
 
Contributor Information and Disclosures
Author

Karim Rasheed, MD, MSc Medical Director, Sani Eye Center

Karim Rasheed, MD, MSc is a member of the following medical societies: American Academy of Ophthalmology

Disclosure: Nothing to disclose.

Coauthor(s)

Yaron Rabinowitz, MD Chairman, Division of Ophthalmology, Cedars-Sinai Medical Center; Clinical Associate Professor, Departments of Ophthalmology and Pediatrics, University of California, Los Angeles, David Geffen School of Medicine

Disclosure: Nothing to disclose.

Specialty Editor Board

Simon K Law, MD, PharmD Clinical Professor of Health Sciences, Department of Ophthalmology, Jules Stein Eye Institute, University of California, Los Angeles, David Geffen School of Medicine

Simon K Law, MD, PharmD is a member of the following medical societies: American Academy of Ophthalmology, Association for Research in Vision and Ophthalmology, American Glaucoma Society

Disclosure: Nothing to disclose.

Christopher J Rapuano, MD Professor, Department of Ophthalmology, Jefferson Medical College of Thomas Jefferson University; Director of the Cornea Service, Co-Director of Refractive Surgery Department, Wills Eye Hospital

Christopher J Rapuano, MD is a member of the following medical societies: American Academy of Ophthalmology, American Ophthalmological Society, American Society of Cataract and Refractive Surgery, Contact Lens Association of Ophthalmologists, International Society of Refractive Surgery, Cornea Society, Eye Bank Association of America

Disclosure: Serve(d) as a director, officer, partner, employee, advisor, consultant or trustee for: Cornea Society, Allergan, Bausch & Lomb, Bio-Tissue, Shire, TearScience, TearLab<br/>Serve(d) as a speaker or a member of a speakers bureau for: Allergan, Bausch & Lomb, Bio-Tissue, TearScience.

Chief Editor

Hampton Roy, Sr, MD Associate Clinical Professor, Department of Ophthalmology, University of Arkansas for Medical Sciences

Hampton Roy, Sr, MD is a member of the following medical societies: American Academy of Ophthalmology, American College of Surgeons, Pan-American Association of Ophthalmology

Disclosure: Nothing to disclose.

Additional Contributors

Fernando H Murillo-Lopez, MD Senior Surgeon, Unidad Privada de Oftalmologia CEMES

Fernando H Murillo-Lopez, MD is a member of the following medical societies: American Academy of Ophthalmology

Disclosure: Nothing to disclose.

References
  1. Oie Y, Maeda N, Kosaki R, Suzaki A, Hirohara Y, Mihashi T, et al. Characteristics of ocular higher-order aberrations in patients with pellucid marginal corneal degeneration. J Cataract Refract Surg. 2008 Nov. 34(11):1928-34. [Medline].

  2. Ertan A, Bahadir M. J. Intrastromal ring segment insertion using a femtosecondlaser to correct pellucid marginal corneal degeneration. J Cataract Refract Surg. 2006 Oct. 32(10):1710-6. [Medline].

  3. Ghajarnia M, Moshirfar M, Mifflin MD. Descemet detachment after femtosecond-laser-assisted placement of intrastromal ring segments in pellucid marginal degeneration. J Cataract Refract Surg. 2008 Dec. 34(12):2174-6. [Medline].

  4. Rasheed K, Rabinowitz YS. Results of combined lamellar and penetrating keratoplasty for pellucid marginal degeneration [abstr]. Ophthalmol Suppl. 1997. Oct:191.

  5. Javadi MA, Karimian F, Hosseinzadeh A, Noroozizadeh HM, Sa'eedifar MR, Rabie HM, et al. Lamellar crescentic resection for pellucid marginal corneal degeneration. J Refract Surg. 2004 Mar-Apr. 20(2):162-5. [Medline].

  6. Krachmer JH. Pellucid marginal corneal degeneration. Arch Ophthalmol. 1978 Jul. 96(7):1217-21. [Medline].

  7. Kymionis GD, Aslanides IM, Siganos CS, Pallikaris IG. Intacs for early pellucid marginal degeneration. J Cataract Refract Surg. 2004 Jan. 30(1):230-3. [Medline].

  8. Maccheron LJ, Daya SM. Wedge resection and lamellar dissection for pellucid marginal degeneration. Cornea. 2012 Jun. 31(6):708-15. [Medline].

  9. Maguire LJ, Klyce SD, McDonald MB, Kaufman HE. Corneal topography of pellucid marginal degeneration. Ophthalmology. 1987 May. 94(5):519-24. [Medline].

  10. Rabinowitz YS. Keratoconus. Surv Ophthalmol. 1998 Jan-Feb. 42(4):297-319. [Medline].

  11. Schanzlin DJ, Sarno EM, Robin JB. Crescentic lamellar keratoplasty for pellucid marginal degeneration. Am J Ophthalmol. 1983 Aug. 96(2):253-4. [Medline].

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Slit lamp image of the inferior cornea in a patient with advanced pellucid marginal degeneration. Image illustrates inferior corneal thinning, a hallmark of this disease.
Corneal topography of early (right eye) and moderate (left eye) pellucid marginal degeneration.
Optical coherence tomography (OCT) of cornea with moderate pellucid marginal degeneration.
Image shows simultaneous central penetrating keratoplasty and inferior peripheral lamellar keratoplasty performed to treat pellucid marginal degeneration.
 
 
 
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