Congenital Clouding of the Cornea Follow-up

  • Author: Noah S Scheinfeld, MD, JD, FAAD; Chief Editor: Hampton Roy Sr, MD   more...
 
Updated: Jul 22, 2011
 

Further Outpatient Care

  • An ophthalmologist should provide regular follow-up care for patients with graft rejection.
  • In addition, a pediatrician should monitor patients for other congenital anomalies.
  • Patients should receive visual rehabilitation as needed.
  • A pediatric contact lens specialist should fit patients with aphakic contact lenses.
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Inpatient & Outpatient Medications

  • Medications may be indicated for treatment after corneal transplantation.
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Complications

  • Complications of corneal transplantation are varied.
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Prognosis

  • The visual prognosis is guarded.
  • The earlier keratoplasty is performed (generally prior to 3-6 months of age), the better the likelihood of preventing deprivation amblyopia.
    • In most series, visual acuity in patients after keratoplasty was 20/80 or worse. Some investigators reported visual acuity of 20/40 in patients.
    • Also, in most series, the likelihood that patients maintain a clear graft was 30-50% at 10 years.
  • Patients with glaucoma and cataract had a worsened prognosis.
  • The prognosis for life depends on other systemic anomalies.
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Patient Education

  • Children with Peters anomaly and other genetic syndromes associated with corneal opacities require special educational assistance depending on their visual outcome. A low-vision specialist should evaluate these children.
  • Patients may need loupes and binoculars depending on their visual potential.
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Contributor Information and Disclosures
Author

Noah S Scheinfeld, MD, JD, FAAD  Assistant Clinical Professor, Department of Dermatology, Columbia University College of Physicians and Surgeons; Consulting Staff, Department of Dermatology, St Luke's Roosevelt Hospital Center, Beth Israel Medical Center, and New York Eye and Ear Infirmary; Private Practice

Noah S Scheinfeld, MD, JD, FAAD is a member of the following medical societies: American Academy of Dermatology

Disclosure: Optigenex Consulting fee Independent contractor

Coauthor(s)

Benjamin D Freilich, MD, FACS  Assistant Clinical Professor, Department of Ophthalmology, Mount Sinai School of Medicine; Director of Retina Service, Bronx Veterans Administration Medical Center

Disclosure: Nothing to disclose.

Jonathan Freilich, MD, FACS  Clinical Instructor, Department of Ophthalmology, Mount Sinai School of Medicine; Consulting Staff, Department of Ophthalmology, Mount Sinai Hospital, St Luke's Roosevelt Hospital Center

Disclosure: Nothing to disclose.

Specialty Editor Board

Richard W Allinson, MD  Associate Professor, Department of Ophthalmology, Texas A&M University Health Science Center; Senior Staff Ophthalmologist, Scott and White Clinic

Richard W Allinson, MD, is a member of the following medical societies: American Academy of Ophthalmology, American Medical Association, and Texas Medical Association

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD  Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Medscape Salary Employment

Christopher J Rapuano, MD  Professor, Department of Ophthalmology, Jefferson Medical College of Thomas Jefferson University; Director of the Cornea Service, Co-Director of Refractive Surgery Department, Wills Eye Institute

Christopher J Rapuano, MD is a member of the following medical societies: American Academy of Ophthalmology, American Society of Cataract and Refractive Surgery, Contact Lens Association of Ophthalmologists, Cornea Society, Eye Bank Association of America, International Society of Refractive Surgery, and Pan-American Association of Ophthalmology

Disclosure: Allergan Honoraria Speaking and teaching; Allergan Consulting fee Consulting; Alcon Honoraria Speaking and teaching; Inspire Honoraria Speaking and teaching; RPS Ownership interest Other; Vistakon Honoraria Speaking and teaching; EyeGate Pharma Consulting; Inspire Consulting fee Consulting; Bausch & Lomb Honoraria Speaking and teaching; Bausch & Lomb Consulting fee Consulting

Ralph Garzia, OD  Assistant Dean for Clinical and Academic Programs, Associate Professor, College of Optometry, University of Missouri at St Louis

Ralph Garzia, OD is a member of the following medical societies: American Academy of Optometry and American Optometric Association

Disclosure: Nothing to disclose.

Chief Editor

Hampton Roy Sr, MD  Associate Clinical Professor, Department of Ophthalmology, University of Arkansas for Medical Sciences

Hampton Roy Sr, MD is a member of the following medical societies: American Academy of Ophthalmology, American College of Surgeons, and Pan-American Association of Ophthalmology

Disclosure: Nothing to disclose.

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