Oculomotor Nerve Palsy Follow-up

  • Author: James Goodwin, MD; Chief Editor: Hampton Roy Sr, MD   more...
 
Updated: Dec 18, 2009
 

Further Inpatient Care

  • Inpatient management of berry aneurysm is up to the discretion of the neurosurgeon.
  • There are no ophthalmological indications for inpatient care.
  • Management of meningitis or systemic cancer may require inpatient care at the discretion of the internist, neurologist, or oncologist treating the case.
Next

Further Outpatient Care

  • Ophthalmologic outpatient follow-up care is the routine for patients with ischemic (pupil-sparing) third cranial nerve palsy.
    • These patients should have routine visits every month or so until the palsy remits. This is mainly to provide symptomatic intervention as is warranted at different stages and to document eventual recovery.
    • Patients who do not recover function after 12-16 weeks may need further diagnostic workup to look for alternative diagnoses.
    • Long-term follow-up care is mainly for those patients who do not recover and for those patients who may require eye muscle surgery for residual, stable diplopia or ptosis.
Previous
Next

Complications

  • Sudden full rupture of berry aneurysm with massive subarachnoid hemorrhage may lead to devastating neurologic deficit and death.
    • This rupture is one of the most serious emergencies that patients presenting with isolated third cranial nerve palsy may develop, and it constitutes the compelling reason for careful differential diagnosis.
    • In much the same way, the natural history of all the diseases mentioned in this article might be listed as complications of third cranial nerve palsy but will not be further elaborated here.
Previous
Next

Prognosis

  • The prognosis depends upon the etiological diagnosis in the individual case. Medical third cranial nerve palsy from presumed ischemia carries the best prognosis for recovery of nerve function, as almost all of these patients recovery spontaneously within a few weeks.
  • Patients with third cranial nerve palsy from identifiable diseases, such as infectious or neoplastic meningeal infiltration and berry aneurysm, have varying prognosis depending on a myriad of factors that are beyond the scope of this article.
Previous
 
Contributor Information and Disclosures
Author

James Goodwin, MD  Associate Professor, Departments of Neurology and Ophthalmology, University of Illinois College of Medicine; Director, Neuro-Ophthalmology Service, University of Illinois Eye and Ear Infirmary

James Goodwin, MD is a member of the following medical societies: American Academy of Neurology, Illinois State Medical Society, North American Neuro-Ophthalmology Society, and Royal Society of Medicine

Disclosure: Nothing to disclose.

Specialty Editor Board

Edsel Ing, MD, FRCSC  Associate Professor, Department of Ophthalmology and Vision Sciences, University of Toronto Faculty of Medicine; Consulting Staff, Toronto East General Hospital, Canada

Edsel Ing, MD, FRCSC is a member of the following medical societies: American Academy of Ophthalmology, American Association for Pediatric Ophthalmology and Strabismus, American Society of Ophthalmic Plastic and Reconstructive Surgery, Canadian Ophthalmological Society, North American Neuro-Ophthalmology Society, and Royal College of Physicians and Surgeons of Canada

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD  Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Medscape Salary Employment

Brian R Younge, MD  Professor of Ophthalmology, Mayo Clinic School of Medicine

Brian R Younge, MD is a member of the following medical societies: American Medical Association, American Ophthalmological Society, and North American Neuro-Ophthalmology Society

Disclosure: Nothing to disclose.

Lance L Brown, OD, MD  Ophthalmologist, Affiliated With Freeman Hospital and St John's Hospital, Regional Eye Center, Joplin, Missouri

Disclosure: Nothing to disclose.

Chief Editor

Hampton Roy Sr, MD  Associate Clinical Professor, Department of Ophthalmology, University of Arkansas for Medical Sciences

Hampton Roy Sr, MD is a member of the following medical societies: American Academy of Ophthalmology, American College of Surgeons, and Pan-American Association of Ophthalmology

Disclosure: Nothing to disclose.

References
  1. Warwick R. Representation of the extraocular muscles in the oculomotor nuclei of the monkey. J Comp Neurol. Jun 1953;98(3):449-503. [Medline].

  2. Vieira JP, Castro J, Gomes LB, et al. Ophthalmoplegic migraine and infundibular dilatation of a cerebral artery. Headache. Oct 2008;48(9):1372-4. [Medline].

  3. Bharucha DX, Campbell TB, Valencia I, et al. MRI findings in pediatric ophthalmoplegic migraine: a case report and literature review. Pediatr Neurol. Jul 2007;37(1):59-63. [Medline].

  4. Acierno MD, Trobe JD, Cornblath WT, et al. Painful oculomotor palsy caused by posterior-draining dural carotid cavernous fistulas. Arch Ophthalmol. Aug 1995;113(8):1045-9. [Medline].

  5. Bahmani Kashkouli M, Khalatbari MR, Yahyavi ST, et al. Pituitary apoplexy presenting as acute painful isolated unilateral third cranial nerve palsy. Arch Iran Med. Jul 2008;11(4):466-8. [Medline].

  6. Quisling SV, Shah VA, Lee HK, et al. Magnetic resonance imaging of third cranial nerve palsy and trigeminal sensory loss caused by herpes zoster. J Neuroophthalmol. Mar 2006;26(1):47-8. [Medline].

  7. Yamada K, Shiga K, Kizu O. Oculomotor nerve palsy evaluated by diffusion-tensor tractography. Neuroradiology. Mar 15 2006;[Medline].

  8. Chen W, Yang Y, Xing W, et al. Sixteen-row multislice computed tomography angiography in the diagnosis and characterization of intracranial aneurysms: comparison with conventional angiography and intraoperative findings. J Neurosurg. Jun 2008;108(6):1184-91. [Medline].

  9. Uysal E, Oztora F, Ozel A, et al. Detection and evaluation of intracranial aneurysms with 16-row multislice CT angiography: comparison with conventional angiography. Emerg Radiol. Sep 2008;15(5):311-6. [Medline].

  10. Asbury AK, Aldredge H, Hershberg R, et al. Oculomotor palsy in diabetes mellitus: a clinico-pathological study. Brain. 1970;93(3):555-66. [Medline].

  11. Trobe JD. Isolated pupil-sparing third nerve palsy. Ophthalmology. Jan 1985;92(1):58-61. [Medline].

  12. Jacobson DM, McCanna TD, Layde PM. Risk factors for ischemic ocular motor nerve palsies. Arch Ophthalmol. Jul 1994;112(7):961-6. [Medline].

  13. Trobe JD. Third nerve palsy and the pupil. Footnotes to the rule. Arch Ophthalmol. May 1988;106(5):601-2. [Medline].

  14. Jacobson DM. Pupil involvement in patients with diabetes-associated oculomotor nerve palsy. Arch Ophthalmol. Jun 1998;116(6):723-7. [Medline].

  15. Daniell MD, Gregson RM, Lee JP. Management of fixed divergent squint in third nerve palsy using traction sutures. Aust N Z J Ophthalmol. Aug 1996;24(3):261-5. [Medline].

  16. Chen PR, Amin-Hanjani S, Albuquerque FC, et al. Outcome of oculomotor nerve palsy from posterior communicating artery aneurysms: comparison of clipping and coiling. Neurosurgery. Jun 2006;58(6):1040-6; discussion 1040-6. [Medline].

  17. Leivo S, Hernesniemi J, Luukkonen M, et al. Early surgery improves the cure of aneurysm-induced oculomotor palsy. Surg Neurol. May 1996;45(5):430-4. [Medline].

  18. Burgess AW, Scheraga HA. A hypothesis for the pathway of the thermally-induced unfolding of bovine pancreatic ribonuclease. J Theor Biol. Sep 1975;53(2):403-20. [Medline].

  19. Jacobson DM, Broste SK. Early progression of ophthalmoplegia in patients with ischemic oculomotor nerve palsies. Arch Ophthalmol. Dec 1995;113(12):1535-7. [Medline].

  20. Keane JR. Aneurysms and third nerve palsies. Ann Neurol. Dec 1983;14(6):696-7. [Medline].

  21. Keane JR, Ahmadi J. Third-nerve palsies and angiography. Arch Neurol. May 1991;48(5):470. [Medline].

  22. Miller NR. The ocular motor nerves. Curr Opin Neurol. Feb 1996;9(1):21-5. [Medline].

  23. Trobe JD. Isolated third nerve palsies. Semin Neurol. Jun 1986;6(2):135-41. [Medline].

Previous
Next
 
Angiography anteroposterior and lateral views, left posterior communicating artery aneurysm, indicated by red arrow. Courtesy of James Goodwin, MD.
Patient with left posterior communicating artery aneurysm and third cranial nerve palsy. Courtesy of James Goodwin, MD.
 
 
 
All material on this website is protected by copyright, Copyright © 1994-2012 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.

DISCLAIMER: The content of this Website is not influenced by sponsors. The site is designed primarily for use by qualified physicians and other medical professionals. The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for educational and informational purposes only. In no way should it be considered as offering medical advice. Please check with a physician if you suspect you are ill.