Acquired Esotropia Treatment & Management
- Author: Mauro Fioretto, MD; Chief Editor: Hampton Roy, Sr, MD more...
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- The treatment of the patient with strabismus is based on the underlying cause. In the absence of organic pathology, the treatment plan is formulated based on the interpretation and analysis of the motility examination results and the overall ocular evaluation. Besides the establishment and stabilization of single binocular vision, the significance of normal ocular alignment for the development of a positive self-image and interpersonal eye contact cannot be overemphasized. The goals of treatment may include the following:
- Obtaining optimal visual acuity in each eye
- Obtaining and/or improving fusion
- Obtaining a favorable functional appearance of the alignment of the eyes
- Indications for and specific types of treatment need to be individualized for each patient. The treatment of the patient with strabismus may include any or all of the following:
- Optical correction
- Added lens power
- Prisms to eliminate diplopia and to reestablish binocular vision
- Active orthoptics/vision therapy
- Amblyopia treatment
- Pharmacologic agents
- Extraocular muscle surgery in stable deviations too large to allow spontaneous binocular fusion
Prescribing the full hypermetropic correction determined by cycloplegic refraction forms an essential part of initial management. Undercorrection of hyperopia remains a common cause of acquired esotropia. Prism adaptation may be of some value in reducing the frequency of surgical undercorrection in nonaccommodative cases; however, published data, including the results of the Prism Adaptation Study, indicate persistent undercorrection rates of nearly 20%. Other approaches, including modifying dosage tables, operating for the near angle, and augmenting surgery based on the accommodative component, have been proposed and supported by data from a number of small clinical series. A review of published experience shows that augmentation of surgery using a combination of these approaches can provide excellent results.
- In patients with acquired esotropia, surgery is indicated when the deviation is greater than 15 PD and stable. If lateral rectus muscle weakness, incomitance, papilledema, or systemic neurologic deficit is evident, neuroimaging studies of the orbits and brain should be performed. Hyperopia greater than +1.50 D or any significant astigmatic refractive error should be treated with glasses prior to performing surgery. Because binocular vision commonly develops before esotropia, surgery is recommended to reestablish binocularity as soon as the pathological underlying causes are eliminated.
- Pediatric strabismus surgery is performed under general anesthesia. The presence of any medical condition that precludes anesthetic administration or any life-threatening cause of esotropia (eg, brain tumor) should delay surgery.
- Bilateral medial rectus recession is performed most commonly for correction of nonaccommodative esotropia. Initial surgery is designed to correct the entire deviation. Monocular medial rectus recession and lateral rectus resection or unilateral medial rectus recession alone also have been used successfully in this situation.
- Expected surgical results
- Clark and colleagues reported good surgical results with bilateral medial rectus recession in 5 of 6 patients with acquired esotropia. Follow-up ranged from 3 months to 3 years. All 5 patients were orthophoric, and 4 of 5 patients had 40 seconds of stereopsis. The sixth patient had a recurrent esotropia of 25 D.
- Kittleman and Mazow achieved a functional cure (defined as alignment of the visual axes within 10 PD of orthophoria) in 66% of patients. They achieved a cosmetic cure (defined as alignment of the visual axes within 18 PD of orthophoria) in an additional 17% of patients. Seven patients required reoperation for a horizontal deviation. Some form of fusion was obtained in 85% of these patients, and 52% of patients obtained some degree of stereopsis.
- Schoffler and Sturm studied 4 children with acute acquired concomitant esotropia who underwent repeated surgery for the sake of binocularity. In all 4 patients, the final binocularity outcome, after repeated surgery, was high-grade stereopsis (Lang I/II positive). The duration from onset of esotropia to the time of regained stereovision was between 20 and 62 months. High-grade stereoacuity was only achieved after a second surgery in one patient. Their findings support the good binocular potential in patients with this type of acute acquired concomitant estropia. In this study, all 4 patients regained high-grade stereopsis, though they did have a complicated course and long-lasting absence of stereovision.
- According to Clark and colleagues, medial rectus pulley posterior fixation, a technique of suturing the pulley to its muscle without scleral sutures, may be as effective as traditional scleral posterior fixation in primary treatment of acquired esotropia with a high AC/A ratio.
- Unilateral or bilateral lateral rectus resection is commonly performed for the correction of an eventual residual esotropia after bilateral medial rectus recession. Performing bilateral lateral rectus resection in patients with residual esotropia after bilateral medial rectus recession is considered appropriate because of the high success rate and the provision of a stable alignment during a long-term follow-up period.
Consult a neurologist/neurosurgeon if neurologic abnormalities (eg, tumor, hydrocephalus) are suspected based on clinical and radiologic findings.
Dietary treatment is not useful in treating patients with any form of strabismus.
Physical activity is not useful in treating patients with any form of strabismus. Orthoptics/vision therapy can be very effective in treating patients with some forms of strabismus.
Firth AY. Heroin and diplopia. Addiction. 2005 Jan. 100(1):46-50. [Medline].
Ludwig IH, Smith JF. Presumed sinus-related strabismus. Trans Am Ophthalmol Soc. 2004. 102:159-65; discussion 165-7. [Medline].
[Guideline] American Academy of Ophthalmology Pediatric Ophthalmology/Strabismus Panel. Esotropia and exotropia. San Francisco (CA): American Academy of Ophthalmology. 2007. [Full Text].
Repka MX, Wentworth D. Predictors of prism response during prism adaptation. Prism Adaptation Study Research Group. J Pediatr Ophthalmol Strabismus. 1991 Jul-Aug. 28(4):202-5. [Medline].
Ho TH, Lin MC, Sheu SJ. Surgical treatment of acquired esotropia in patients with high myopia. J Chin Med Assoc. 2012 Aug. 75(8):416-9. [Medline].
Clark AC, Nelson LB, Simon JW. Acute acquired comitant esotropia. Br J Ophthalmol. 1989 Aug. 73(8):636-8. [Medline].
Kittleman WT, Mazow ML. Reoperations in esotropia surgery. Ann Ophthalmol. 1986 May. 18(5):174-7. [Medline].
Schoffler C, Sturm V. Repeated surgery for acute acquired esotropia: is it worth the effort?. Eur J Ophthalmol. 2009 Dec 16. [Medline].
Clark RA, Ariyasu R, Demer JL. Medial rectus pulley posterior fixation: a novel technique to augment recession. J AAPOS. 2004 Oct. 8(5):451-6. [Medline].
Jang GJ, Park MR, Park SC. Bilateral lateral rectus resection in patients with residual esotropia. Korean J Ophthalmol. 2004 Dec. 18(2):161-7. [Medline].
Costello PA, Simon JW, Jia Y, Lininger LL. Acquired esotropia: subjective and objective outcomes. J AAPOS. 2001 Jun. 5(3):193-7. [Medline].
Fukai S, Arai N, Hayakawa T, Kimura H. Studies on the botulinum therapy for esotropia improvement of retinal correspondence. Nippon Ganka Gakkai Zasshi. 1993 Jun. 97(6):757-62. [Medline].
Goldman HD, Nelson LB. Acute acquired comitant esotropia. Ann Ophthalmol. 1985 Dec. 17(12):777-8. [Medline].
Lyons CJ, Tiffin PA, Oystreck D. Acute acquired comitant esotropia: a prospective study. Eye. 1999 Oct. 13 (Pt 5):617-20. [Medline].
Mohney BG. Acquired nonaccommodative esotropia in childhood. J AAPOS. 2001 Apr. 5(2):85-9. [Medline].
Mohney BG. Common forms of childhood esotropia. Ophthalmology. 2001 Apr. 108(4):805-9. [Medline].
Thomas AH. Divergence insufficiency. J AAPOS. 2000 Dec. 4(6):359-61. [Medline].
Troost BT, Abel L, Noreika J, Genovese FM. Acquired cyclic esotropia in an adult. Am J Ophthalmol. 1981 Jan. 91(1):8-13. [Medline].