Infantile Esotropia Follow-up

  • Author: Vicente Victor D Ocampo Jr, MD; Chief Editor: Hampton Roy Sr, MD   more...
 
Updated: Feb 17, 2010
 

Further Outpatient Care

  • The infant typically is seen 3-10 days after the surgery. Visual acuity is checked, an afferent pupillary defect is ruled out, and a good red reflex is elicited from both fundi. Furthermore, conjunctival incisions are inspected with a penlight for dehiscence and infection. Most importantly, alignment is assessed, and eye movements are observed for gross underaction and a slipped muscle. If no excessive inflammation is noted, use of antibiotic-corticosteroid ointments may be stopped at this time.
  • Surgical correction is the first step in the visual rehabilitation of children with infantile esotropia. Patients who are aligned successfully early in life still need careful postoperative monitoring for amblyopia, nystagmus, inferior oblique overactions, dissociated vertical divergence, and accommodative esotropia.
  • A follow-up visit usually is scheduled 3-4 months after the initial postoperative consult. At this point, occlusion therapy can be restarted if amblyopia is present. In cases of significant overcorrection or undercorrection, while the patient may be seen earlier, reoperations seldom are performed before the third to fourth month postoperative period. If alignment is optimal (eg, within 8 PD of orthophoria) and acuity is equal in both eyes, subsequent follow-up visits are scheduled every 6 months until age 6 years. At this point, the risk of strabismic amblyopia is decreased, and yearly visits are sufficient. After age 10, consultations are performed on an as-needed basis.
  • Accommodative esotropia may develop following surgical correction of infantile esotropia. In a study by Uretmen et al, it was noted that accommodative esotropia occurred at a mean of 8.8 months (range, 6-24 mo) after the initial surgical alignment, with a mean age of onset of 43.2 months.[23] Correction with the appropriate lenses must be instituted to prevent the adverse effects of accommodative esotropia on sensory and motor functions.
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Inpatient & Outpatient Medications

  • Aside from the antibiotic-steroid ointment used in the immediate postoperative period, no other medications are needed.
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Complications

  • Complications of initial surgical correction of infantile esotropia include the following:
    • Marked overcorrection and undercorrection
    • Infection
    • Scleral perforation
    • Foreign body granuloma at the suture site
    • Allergic reaction to suture material
    • Conjunctival inclusion cyst
    • Conjunctival scarring
    • Anterior segment ischemia
    • Change in eyelid position
    • Lost muscle
    • Slipped muscle
    • Oculocardiac reflex
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Prognosis

  • It is accepted that better ocular alignment and visual prognosis can be achieved if surgical correction is performed before age 2 years. Long-term follow-up studies on esotropic infants who underwent surgical alignment by age 2 years have shown that close to 60% achieve a small angle (< 20 PD) cosmetically acceptable strabismus. Although some binocular vision is achieved, it generally is subnormal, often involving peripheral fusion. Factors contributing to poor ocular alignment and visual prognosis include persistent preoperative amblyopia, latent manifest nystagmus, and myopia from -2.5 to 5.0 D.
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Patient Education

  • Parents and other caregivers must be educated on the various presentations of infantile esotropia to ensure early detection and management.
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Contributor Information and Disclosures
Author

Vicente Victor D Ocampo Jr, MD  Head, Uveitis and Ocular Immunology Service, Veterans Memorial Medical Center, Philippines; Head, Uveitis and Ocular Immunology Service, Ospital ng Makati Medical Center, Philippines; Consulting Staff, Department of Ophthalmology, Asian Hospital and Medical Center, Philippines

Vicente Victor D Ocampo Jr, MD is a member of the following medical societies: American Academy of Ophthalmology, Philippine Academy of Ophthalmology, and Philippine Ocular Inflammation Society

Disclosure: Nothing to disclose.

Coauthor(s)

C Stephen Foster, MD, FACS, FACR, FAAO  Clinical Professor of Ophthalmology, Harvard Medical School; Consulting Staff, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary; Founder and President, Ocular Immunology and Uveitis Foundation, Massachusetts Eye Research and Surgery Institution

C Stephen Foster, MD, FACS, FACR, FAAO is a member of the following medical societies: Alpha Omega Alpha, American Academy of Ophthalmology, American Association of Immunologists, American College of Rheumatology, American College of Surgeons, American Federation for Clinical Research, American Medical Association, American Society for Microbiology, American Uveitis Society, Association for Research in Vision and Ophthalmology, Massachusetts Medical Society, Royal Society of Medicine, and Sigma Xi

Disclosure: Nothing to disclose.

Specialty Editor Board

Gerhard W Cibis, MD  Clinical Professor, Director of Pediatric Ophthalmology Service, Department of Ophthalmology, University of Kansas School of Medicine

Gerhard W Cibis, MD is a member of the following medical societies: American Academy of Ophthalmology, American Association for Pediatric Ophthalmology and Strabismus, and American Ophthalmological Society

Disclosure: Nothing to disclose.

Simon K Law, MD, PharmD  Associate Professor of Ophthalmology, Jules Stein Eye Institute, University of California, Los Angeles, David Geffen School of Medicine

Simon K Law, MD, PharmD is a member of the following medical societies: American Academy of Ophthalmology, American Glaucoma Society, and Association for Research in Vision and Ophthalmology

Disclosure: Nothing to disclose.

J James Rowsey, MD  Former Director of Corneal Services, St Luke's Cataract and Laser Institute

J James Rowsey, MD is a member of the following medical societies: American Academy of Ophthalmology, American Association for the Advancement of Science, American Medical Association, Association for Research in Vision and Ophthalmology, Florida Medical Association, Pan-American Association of Ophthalmology, Sigma Xi, and Southern Medical Association

Disclosure: Nothing to disclose.

Lance L Brown, OD, MD  Ophthalmologist, Affiliated With Freeman Hospital and St John's Hospital, Regional Eye Center, Joplin, Missouri

Disclosure: Nothing to disclose.

Chief Editor

Hampton Roy Sr, MD  Associate Clinical Professor, Department of Ophthalmology, University of Arkansas for Medical Sciences

Hampton Roy Sr, MD is a member of the following medical societies: American Academy of Ophthalmology, American College of Surgeons, and Pan-American Association of Ophthalmology

Disclosure: Nothing to disclose.

References
  1. Louwagie CR, Diehl NN, Greenberg AE, Mohney BG. Is the incidence of infantile esotropia declining?: a population-based study from Olmsted County, Minnesota, 1965 to 1994. Arch Ophthalmol. Feb 2009;127(2):200-3. [Medline].

  2. Nixon RB, Helveston EM, Miller K, et al. Incidence of strabismus in neonates. Am J Ophthalmol. Dec 15 1985;100(6):798-801. [Medline].

  3. Greenberg AE, Mohney BG, Diehl NN, Burke JP. Incidence and types of childhood esotropia: a population-based study. Ophthalmology. Jan 2007;114(1):170-4. [Medline].

  4. Tychsen L. Infantile esotropia: Current neurophysiologic concepts. In: Clinical Strabismus Management: Principles and Surgical Techniques. 1999:117-138.

  5. Weakley DR, Urso RG, Dias CL. Asymmetric inferior oblique overaction and its association with amblyopia in esotropia. Ophthalmology. Apr 1992;99(4):590-3. [Medline].

  6. Mohindra I, Zwaan J, Held R, et al. Development of acuity and stereopsis in infants with esotropia. Ophthalmology. May 1985;92(5):691-7. [Medline].

  7. Haefliger IO, Safran AB, Mermillod B, Roth A. Inferonasal quadrant of the visual field is not constricted in patients with infantile esotropia when evaluated by means of automated perimetry. J Clin Neuroophthalmol. Jun 1990;10(2):118-20. [Medline].

  8. McNeer KW, Spencer RF, Tucker MG. Observations on bilateral simultaneous botulinum toxin injection in infantile esotropia. J Pediatr Ophthalmol Strabismus. Jul-Aug 1994;31(4):214-9. [Medline].

  9. McNeer KW, Tucker MG, Spencer RF. Botulinum toxin management of essential infantile esotropia in children. Arch Ophthalmol. Nov 1997;115(11):1411-8. [Medline].

  10. Scott AB, Magoon EH, McNeer KW, Stager DR. Botulinum treatment of childhood strabismus. Ophthalmology. Nov 1990;97(11):1434-8. [Medline].

  11. Tejedor J, Rodriguez JM. Early retreatment of infantile esotropia: comparison of reoperation and botulinum toxin. Br J Ophthalmol. Jul 1999;83(7):783-7. [Medline].

  12. Ing MR. Botulinum alignment for congenital esotropia. Ophthalmology. Mar 1993;100(3):318-22. [Medline].

  13. Biglan AW, Burnstine RA, Rogers GL, Saunders RA. Management of strabismus with botulinum A toxin. Ophthalmology. Jul 1989;96(7):935-43. [Medline].

  14. Rowe FJ, Noonan CP. Botulinum toxin for the treatment of strabismus. Cochrane Database Syst Rev. Apr 15 2009;CD006499. [Medline].

  15. Polling JR, Eijkemans MJ, Esser J, Gilles U, Kolling GH, Schulz E, et al. A randomised comparison of bilateral recession versus unilateral recession-resection as surgery for infantile esotropia. Br J Ophthalmol. Jul 2009;93(7):954-7. [Medline].

  16. Chang YH, Ryu IH, Han SH, et al. Intraoperative adjustment in strabismus surgery under topical anesthesia. Yonsei Med J. Oct 31 2006;47(5):667-71. [Medline].

  17. Zak TA, Morin JD. Early surgery for infantile esotropia: results and influence of age upon results. Can J Ophthalmol. Oct 1982;17(5):213-8. [Medline].

  18. Shirabe H, Mori Y, Dogru M, Yamamoto M. Early surgery for infantile esotropia. Br J Ophthalmol. May 2000;84(5):536-8. [Medline].

  19. Birch EE, Fawcett S, Stager DR. Why does early surgical alignment improve stereoacuity outcomes in infantile esotropia?. J AAPOS. Feb 2000;4(1):10-4. [Medline].

  20. Lueder GT, Norman AA. Strabismus surgery for elimination of bifocals in accommodative esotropia. Am J Ophthalmol. Oct 2006;142(4):632-5. [Medline].

  21. Ticho BH, Ticho KE, Kaufman LM. Combined strabismus and lens surgery. J AAPOS. Oct 2006;10(5):430-4. [Medline].

  22. Godts D, Trau R, Tassignon MJ. Effect of refractive surgery on binocular vision and ocular alignment in patients with manifest or intermittent strabismus. Br J Ophthalmol. Nov 2006;90(11):1410-3. [Medline].

  23. Uretmen O, Civan BB, Kose S, Yuce B, Egrilmez S. Accommodative esotropia following surgical treatment of infantile esotropia: frequency and risk factors. Acta Ophthalmol. May 2008;86(3):279-83. [Medline].

  24. Birch E, Stager D, Wright K, Beck R. The natural history of infantile esotropia during the first six months of life. Pediatric Eye Disease Investigator Group. J AAPOS. Dec 1998;2(6):325-8; discussion 329. [Medline].

  25. Birch EE, Stager DR. Monocular acuity and stereopsis in infantile esotropia. Invest Ophthalmol Vis Sci. Nov 1985;26(11):1624-30. [Medline].

  26. Clarke WN, Noel LP. Vanishing infantile esotropia. Can J Ophthalmol. Jun 1982;17(3):100-2. [Medline].

  27. Drover JR, Stager DR Sr, Morale SE, Leffler JN, Birch EE. Improvement in motor development following surgery for infantile esotropia. J AAPOS. Apr 2008;12(2):136-40. [Medline].

  28. Friendly DS. Management of infantile esotropia. Int Ophthalmol Clin. 1985;25(4):37-52. [Medline].

  29. Gerth C, Mirabella G, Li X, Wright T, Westall C, Colpa L, et al. Timing of surgery for infantile esotropia in humans: effects on cortical motion visual evoked responses. Inv Ophth Vis Sci. Aug 2008;49(8):3432-7. [Full Text].

  30. Hiles DA, Watson BA, Biglan AW. Characteristics of infantile esotropia following early bimedial rectus recession. Arch Ophthalmol. Apr 1980;98(4):697-703. [Medline].

  31. Hunter DG, Ellis FJ. Prevalence of systemic and ocular disease in infantile exotropia: comparison with infantile esotropia. Ophthalmology. Oct 1999;106(10):1951-6. [Medline].

  32. Ing MR. The timing of surgical alignment for congenital (infantile) esotropia. J Pediatr Ophthalmol Strabismus. Mar-Apr 1999;36(2):61-8; quiz 85-6. [Medline].

  33. Khan AO. Cycloplegic refractions as a function of age in children with infantile esotropia. Binocul Vis Strabismus Q. 2009;24(1):39-42. [Medline].

  34. Lueder GT, Galli ML. Effect of preoperative stability of alignment on outcome of strabismus surgery for infantile esotropia. J AAPOS. Feb 2008;12(1):66-8. [Medline].

  35. Major A, Maples WC, Toomey S, DeRosier W, Gahn D. Variables associated with the incidence of infantile esotropia. Optometry. Oct 2007;78(10):534-41. [Medline].

  36. O'Keefe M, Abdulla N, Bowell R, Lanigan B. Binocular function and amblyopia after early surgery in infantile eosotropia. Acta Ophthalmol Scand. Oct 1996;74(5):461-2. [Medline].

  37. Ohtsuki H, Yoshifumi K, Hasebe S, et al. Comparative study of brain lesions detected by magnetic resonance imaging between strabismus and nonstrabismus in infancy. Ophthalmologica. 2000;214(2):105-10. [Medline].

  38. Paul TO, Hardage LK. The heritability of strabismus. Ophthalmic Genet. Mar 1994;15(1):1-18. [Medline].

  39. Pott JW, Sprunger DT, Helveston EM. Infantile esotropia in very low birth weight (VLBW) children. Strabismus. Jun 1999;7(2):97-102. [Medline].

  40. Pratt-Johnson JA, Tillson G. Sensory results following treatment of infantile esotropia. Can J Ophthalmol. Jun 1983;18(4):175-7. [Medline].

  41. Prieto-Diaz J, Prieto-Diaz I. Long term outcome of treated congenital/infantile esotropia: does early surgical binocular alignment restoring (subnormal) binocular vision guarantee stability?. Binocul Vis Strabismus Q. 1998;13(4):249-54. [Medline].

  42. Robb RM, Rodier DW. The variable clinical characteristics and course of early infantile esotropia. J Pediatr Ophthalmol Strabismus. Nov-Dec 1987;24(6):276-81. [Medline].

  43. Rowe FJ. Long-term postoperative stability in infantile esotropia. Strabismus. Mar 2000;8(1):3-13. [Medline].

  44. Scheiman M, Ciner E, Gallaway M. Surgical success rates in infantile esotropia. J Am Optom Assoc. Jan 1989;60(1):22-31. [Medline].

  45. Shauly Y, Miller B, Meyer E. Clinical characteristics and long-term postoperative results of infantile esotropia and myopia. J Pediatr Ophthalmol Strabismus. Nov-Dec 1997;34(6):357-64. [Medline].

  46. Shauly Y, Prager TC, Mazow ML. Clinical characteristics and long-term postoperative results of infantile esotropia. Am J Ophthalmol. Feb 15 1994;117(2):183-9. [Medline].

  47. Stager DR, Birch EE. Preferential-looking acuity and stereopsis in infantile esotropia. J Pediatr Ophthalmol Strabismus. Jul-Aug 1986;23(4):160-5. [Medline].

  48. Tolun H, Dikici K, Ozkiris A. Long-term results of bimedial rectus recessions in infantile esotropia. J Pediatr Ophthalmol Strabismus. Jul-Aug 1999;36(4):201-5. [Medline].

  49. Webber AL, Wood JM, Gole GA, Brown B. The effect of amblyopia on fine motor skills in children. Invest Ophthalmol Vis Sci. Feb 2008;49(2):594-603. [Medline].

  50. Wong AM. Timing of surgery for infantile esotropia: sensory and motor outcomes. Can J Ophthalmol. Dec 2008;43(6):643-51. [Medline].

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