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Familial Dysautonomia Follow-up

  • Author: Robert A D'Amico, MD, FACS; Chief Editor: Hampton Roy, Sr, MD  more...
Updated: Jan 05, 2016

Further Outpatient Care

At New York University Medical Center, a Dysautonomia Treatment and Evaluation Center examines patients with familial dysautonomia (FD) on a regular schedule to provide comprehensive care plans. It serves as a resource for patients, families, and health providers.



No means of preventing the disorder exists at this time, but with symptomatic and supportive treatments, morbidity and mortality have been reduced and quality of life enhanced.



Educate parents and patients regarding daily eye care and early warning signs of corneal problems, as well as use of punctal cautery. This education has resulted in decreased corneal scarring and decreased the need for more aggressive surgical measures, such as tarsorrhaphy, conjunctival flaps, and corneal transplants.


Patient Education

Teach patients and parents to instill topical lubricants frequently and to be alert for early warning signs of corneal erosion and infection.

Use eye protective devices (eg, goggles, moisture chambers, scleral lenses) when topical medications are not sufficient.

Contributor Information and Disclosures

Robert A D'Amico, MD, FACS Chairman, Department of Ophthalmology, Richmond University Medical Center; Clinical Professor, Department of Ophthalmology, New York University School of Medicine

Robert A D'Amico, MD, FACS is a member of the following medical societies: Association for Research in Vision and Ophthalmology, Medical Society of the State of New York, New York Academy of Medicine, International Society for Genetic Eye Diseases and Retinoblastoma, Transplantation Society, Cornea Society, Association of University Professors of Ophthalmology, Xenotransplantation Society, American Academy of Ophthalmology, American College of Surgeons, American Medical Association

Disclosure: Nothing to disclose.


Felicia B Axelrod, MD Director of Dysautonomia Treatment and Evaluation Center, Carl Seaman Family Professor for Dysautonomia Treatment and Research, Professor, Departments of Pediatrics and Neurology, New York University School of Medicine

Felicia B Axelrod, MD is a member of the following medical societies: American Academy of Pediatrics, American Autonomic Society, American Medical Association, American Pediatric Society, Society for Pediatric Research

Disclosure: Nothing to disclose.

Specialty Editor Board

Simon K Law, MD, PharmD Clinical Professor of Health Sciences, Department of Ophthalmology, Jules Stein Eye Institute, University of California, Los Angeles, David Geffen School of Medicine

Simon K Law, MD, PharmD is a member of the following medical societies: American Academy of Ophthalmology, Association for Research in Vision and Ophthalmology, American Glaucoma Society

Disclosure: Nothing to disclose.

Chief Editor

Hampton Roy, Sr, MD Associate Clinical Professor, Department of Ophthalmology, University of Arkansas for Medical Sciences

Hampton Roy, Sr, MD is a member of the following medical societies: American Academy of Ophthalmology, American College of Surgeons, Pan-American Association of Ophthalmology

Disclosure: Nothing to disclose.

Additional Contributors

Andrew W Lawton, MD Neuro-Ophthalmology, Ochsner Health Services

Andrew W Lawton, MD is a member of the following medical societies: American Academy of Ophthalmology, Arkansas Medical Society, Southern Medical Association

Disclosure: Nothing to disclose.

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Absence of fungiform papillae on the tongue. The highly vascularized fungiform papillae on the anterior third of the tongue are absent resulting in a smooth and glistening tongue tip.
Lack of axon flare following intradermal histamine. Histamine phosphate in a 1:10,000 dilution injected intradermally does not produce pain or an axon flare.
Erosion and scarring of the inferior cornea due to incomplete lid closure during sleep.
Neurotrophic corneal ulcer.
Corneal stromal opacification.
Bipedicle tarsorrhaphy.
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