eMedicine Specialties > Ophthalmology > Infectious Disease
Ocular Manifestations of Syphilis: Multimedia
Updated: Dec 26, 2007
Multimedia
![]() | Media file 1: Ocular manifestations of syphilis. Interstitial keratitis in a patient with ocular syphilis. |
![]() | Media file 2: Ocular manifestations of syphilis. Interstitial keratitis in a patient with ocular syphilis. |
![]() | Media file 3: Ocular manifestations of syphilis. Syphilis chorioretinitis in a 30-year-old patient who is mentally retarded. |
![]() | Media file 4: Ocular manifestations of syphilis. A 73-year-old female patient with syphilis. Note the optic atrophy, arteriolar narrowing, pigment loss, and clumping. |
![]() | Media file 5: Ocular manifestations of syphilis. Retinal vasculitis in a patient with ocular syphilis. |
![]() | Media file 6: Ocular manifestations of syphilis. Fluorescein angiography of same patient as in Media file 5. |
![]() | Media file 7: Ocular manifestations of syphilis. Chorioretinitis of ocular syphilis. |
![]() | Media file 8: Ocular manifestations of syphilis. Retinal vasculitis of ocular syphilis as seen on fluorescein angiography. |
More on Ocular Manifestations of Syphilis |
| Overview: Ocular Manifestations of Syphilis |
| Differential Diagnoses & Workup: Ocular Manifestations of Syphilis |
| Treatment & Medication: Ocular Manifestations of Syphilis |
| Follow-up: Ocular Manifestations of Syphilis |
Multimedia: Ocular Manifestations of Syphilis |
| References |
| « Previous Page |
References
Garfinkel M, Blumstein H. Gender differences in testing for syphilis in emergency department patients diagnosed with sexually transmitted diseases. J Emerg Med. Nov-Dec 1999;17(6):937-40. [Medline].
Aldave AJ, King JA, Cunningham ET Jr. Ocular syphilis. Curr Opin Ophthalmol. Dec 2001;12(6):433-41. [Medline].
Baglivo E, Kapetanios A, Safran AB. Fluorescein and indocyanine green angiographic features in acute syphilitic macular placoid chorioretinitis. Can J Ophthalmol. Aug 2003;38(5):401-5. [Medline].
Browning DJ. Posterior segment manifestations of active ocular syphilis, their response to a neurosyphilis regimen of penicillin therapy, and the influence of human immunodeficiency virus status on response. Ophthalmology. Nov 2000;107(11):2015-23. [Medline].
Deschenes J, Seamone CD, Baines MG. Acquired ocular syphilis: diagnosis and treatment. Ann Ophthalmol. Apr 1992;24(4):134-8. [Medline].
Diaz-Valle D, Allen DP, Sanchez AA, Aguado CB, Benitez Del Castillo JM, Acenero MJ. Simultaneous bilateral exudative retinal detachment and peripheral necrotizing retinitis as presenting manifestations of concurrent HIV and syphilis infection. Ocul Immunol Inflamm. Dec 2005;13(6):459-62. [Medline].
Dinis da Gama R, Cidade M. Images in clinical medicine. Interstitial keratitis as the initial expression of syphilitic reactivation. N Engl J Med. Jun 6 2002;346(23):1799. [Medline].
Doris JP, Saha K, Jones NP, Sukthankar A. Ocular syphilis: the new epidemic. Eye. Jun 2006;20(6):703-5. [Medline].
Durnian JM, Naylor G, Saeed AM. Ocular syphilis: the return of an old acquaintance. Eye. Apr 2004;18(4):440-2. [Medline].
Edmonds LC, Stubbs SE, Ryu JH. Syphilis: a disease to exclude in diagnosing sarcoidosis. Mayo Clin Proc. Jan 1992;67(1):37-41. [Medline].
Fathilah J, Choo MM. The Jarisch-Herxheimer reaction in ocular syphilis. Med J Malaysia. Aug 2003;58(3):437-9. [Medline].
Goegebuer A, Ajay L, Claerhout I, Kestelyn P. Results of penetrating keratoplasty in syphilitic interstitial keratitis. Bull Soc Belge Ophtalmol. 2003;(290):35-9. [Medline].
Halperin LS, Lewis H, Blumenkranz MS, Gass JD, Olk RJ, Fine SL. Choroidal neovascular membrane and other chorioretinal complications of acquired syphilis. Am J Ophthalmol. Nov 15 1989;108(5):554-62. [Medline].
Hariprasad SM, Moon SJ, Allen RC, Wilhelmus KR. Keratopathy from congenital syphilis. Cornea. Aug 2002;21(6):608-9. [Medline].
Kawaguchi R, Saika S, Wakayama M, Ooshima A, Ohnishi Y, Yabe H. Extracellular matrix components in a case of retrocorneal membrane associated with syphilitic interstitial keratitis. Cornea. Jan 2001;20(1):100-3. [Medline].
Kiss S, Damico FM, Young LH. Ocular manifestations and treatment of syphilis. Semin Ophthalmol. Jul-Sep 2005;20(3):161-7. [Medline].
Margo CE, Hamed LM. Ocular syphilis. Surv Ophthalmol. Nov-Dec 1992;37(3):203-20. [Medline].
Matsuo T, Taira Y, Nagayama M, Baba T. Angle-closure glaucoma as a presumed presenting sign in patients with syphilis. Jpn J Ophthalmol. May-Jun 2000;44(3):305-8. [Medline].
McCall MB, van Lith-Verhoeven JJ, van Crevel R, Crama N, Koopmans PP, Hoyng CB, et al. Ocular syphilis acquired through oral sex in two HIV-infected patients. Neth J Med. Jun 2004;62(6):206-8. [Medline].
Menon SR, Fleischhauer J, Jost K, Helbig H. Clinical and electrophysiological course of acute syphilitic posterior placoid chorioretinitis. Klin Monatsbl Augenheilkd. Mar 2005;222(3):261-3. [Medline].
Moloney G, Branley M, Kotsiou G, Rhodes D. Syphilis presenting as scleritis in an HIV-positive man undergoing immune reconstitution. Clin Experiment Ophthalmol. Oct 2004;32(5):526-8. [Medline].
Mora P, Borruat FX, Guex-Crosier Y. Indocyanine green angiography anomalies in ocular syphilis. Retina. Feb-Mar 2005;25(2):171-81. [Medline].
Morgan CM, Webb RM, O'Connor GR. Atypical syphilitic chorioretinitis and vasculitis. Retina. Fall-Winter 1984;4(4):225-31. [Medline].
Ormerod LD, Puklin JE, Sobel JD. Syphilitic posterior uveitis: correlative findings and significance. Clin Infect Dis. Jun 15 2001;32(12):1661-73. [Medline].
Orsoni JG, Zavota L, Manzotti F. Syphilitic interstitial keratitis: treatment with immunosuppressive drug combination therapy. Cornea. Jul 2004;23(5):530-2. [Medline].
Pao D, Goh BT, Bingham JS. Management issues in syphilis. Drugs. 2002;62(10):1447-61. [Medline].
Passo MS, Rosenbaum JT. Ocular syphilis in patients with human immunodeficiency virus infection. Am J Ophthalmol. Jul 15 1988;106(1):1-6. [Medline].
Peters GB 3rd, Krohel GB. Active ocular syphilis. Ophthalmology. Sep 2001;108(9):1515-6. [Medline].
Physicians' Desk Reference. 53rd ed. Montvale, NJ: Thomson Healthcare; 1999.
Rodriguez-Diaz E, Moran-Estefania M, Lopez-Avila A, Piris JB, Fernandez-Blasco G, Garcia JI, et al. Clinical expression of secondary syphilis in a patient with HIV infection. J Dermatol. Feb 1994;21(2):111-6. [Medline].
Sakai T, Shikishima K, Mizobuchi T, Yoshida M, Kitahara K. Bilateral tonic pupils associated with neurosyphilis. Jpn J Ophthalmol. Jul-Aug 2003;47(4):368-71. [Medline].
Schurmann D, Bergmann F, Bertelmann E, Padberg J, Liekfeld A, Pleyer U. Early diagnosis of acquired ocular syphilis requires a high index of suspicion and may prevent visual loss. AIDS. Apr 1 1999;13(5):623-4. [Medline].
Spoor TC, Wynn P, Hartel WC, Bryan CS. Ocular syphilis. Acute and chronic. J Clin Neuroophthalmol. Sep 1983;3(3):197-203. [Medline].
Tabbara KF, al Kaff AS, Fadel T. Ocular manifestations of endemic syphilis (bejel). Ophthalmology. Jul 1989;96(7):1087-91. [Medline].
Tamesis RR, Foster CS. Ocular syphilis. Ophthalmology. Oct 1990;97(10):1281-7. [Medline].
Thami GP, Kaur S, Gupta R, Kanwar AJ, Sood S. Syphilitic panuveitis and asymptomatic neurosyphilis: a marker of HIV infection. Int J STD AIDS. Nov 2001;12(11):754-6. [Medline].
Tran TH, Cassoux N, Bodaghi B. Syphilitic uveitis in patients infected with human immunodeficiency virus. Graefes Arch Clin Exp Ophthalmol. Sep 2005;243(9):863-9. [Medline].
Williams JK, Kirsch LS, Russack V, Freeman WR. Rhegmatogenous retinal detachments in HIV-positive patients with ocular syphilis. Ophthalmic Surg Lasers. Aug 1996;27(8):699-705. [Medline].
Yokoi M, Kase M. Retinal vasculitis due to secondary syphilis. Jpn J Ophthalmol. Jan-Feb 2004;48(1):65-7. [Medline].
Further Reading
Keywords
ocular syphilis, interstitial keratitis, episcleritis, scleritis, iritis, iris papules, chorioretinitis, papillitis, retinal vasculitis, exudative retinal detachment, primary syphilis, secondary syphilis, latent syphilis, tertiary syphilis, quaternary syphilis, Treponema pallidum, T pallidum, lues, chancre, gumma, sexually transmitted disease, STD, HIV, AIDS
















Multimedia: Ocular Manifestations of Syphilis