eMedicine Specialties > Ophthalmology > Infectious Disease

Actinomycosis: Multimedia

Author: Manolette R Roque, MD, MBA, President and CEO, Service Chief of Ocular Immunology and Uveitis, Refractive Surgery, EYE REPUBLIC Ophthalmology Clinic; General Manager, Ophthalmic Consultants Philippines; Section Chief of Ocular Immunology and Uveitis, Department of Ophthalmology, Asian Hospital and Medical Center; Section Chief of Ocular Immunology and Uveitis, Department of Ophthalmology, St. Luke's Medical Center Global City; Senior Eye Surgeon, The LASIK Surgery Clinic
Coauthor(s): Barbara L Roque, MD, Full Partner, Ophthalmic Consultants Philippines Co, Chief of Service, Pediatric Ophthalmology and Strabismus, Consulting Staff, Orbit and Eye Plastics, Eye Republic Ophthalmology Clinic; C Stephen Foster, MD, FACS, FACR, FAAO, Clinical Professor of Ophthalmology, Harvard Medical School; Consulting Staff, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary; Founder and President, Ocular Immunology and Uveitis Foundation, Massachusetts Eye Research and Surgery Institution
Contributor Information and Disclosures

Updated: Oct 13, 2008

Multimedia

Canaliculitis of the left lower lid. Courtesy of ...Media file 1: Canaliculitis of the left lower lid. Courtesy of Peter Rubin, MD, Director, Eye Plastics Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School.
Canaliculitis of the left lower lid. Courtesy of ...

Canaliculitis of the left lower lid. Courtesy of Peter Rubin, MD, Director, Eye Plastics Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School.

Canaliculitis of the right upper lid. Courtesy of...Media file 2: Canaliculitis of the right upper lid. Courtesy of Peter Rubin, MD, Director, Eye Plastics Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School.
Canaliculitis of the right upper lid. Courtesy of...

Canaliculitis of the right upper lid. Courtesy of Peter Rubin, MD, Director, Eye Plastics Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School.

A pediatric patient with canaliculitis. Courtesy ...Media file 3: A pediatric patient with canaliculitis. Courtesy of Peter Rubin, MD, Director, Eye Plastics Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School.
A pediatric patient with canaliculitis. Courtesy ...

A pediatric patient with canaliculitis. Courtesy of Peter Rubin, MD, Director, Eye Plastics Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School.

A patient presenting with pseudocanaliculitis sec...Media file 4: A patient presenting with pseudocanaliculitis secondary to a chalazion. Courtesy of Peter Rubin, MD, Director, Eye Plastics Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School.
A patient presenting with pseudocanaliculitis sec...

A patient presenting with pseudocanaliculitis secondary to a chalazion. Courtesy of Peter Rubin, MD, Director, Eye Plastics Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School.

A patient presenting with pseudocanaliculitis sec...Media file 5: A patient presenting with pseudocanaliculitis secondary to a chalazion. Courtesy of Peter Rubin, MD, Director, Eye Plastics Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School.
A patient presenting with pseudocanaliculitis sec...

A patient presenting with pseudocanaliculitis secondary to a chalazion. Courtesy of Peter Rubin, MD, Director, Eye Plastics Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School.

Actinomyces israelii (non–spore-forming, gr...Media file 6: Actinomyces israelii (non–spore-forming, gram-positive bacilli). Courtesy of Medical Education Information Center, Department of Pathology and Laboratory Medicine, The University of Texas-Houston Medical School.
Actinomyces israelii (non–spore-forming, gr...

Actinomyces israelii (non–spore-forming, gram-positive bacilli). Courtesy of Medical Education Information Center, Department of Pathology and Laboratory Medicine, The University of Texas-Houston Medical School.

Actinomyces israelii. (The image is labeled.)Media file 7: Actinomyces israelii. (The image is labeled.)
Actinomyces israelii. (The image is labeled.)

Actinomyces israelii. (The image is labeled.)

Actinomycosis.Media file 8: Actinomycosis.
Actinomycosis.

Actinomycosis.

More on Actinomycosis

Overview: Actinomycosis
Differential Diagnoses & Workup: Actinomycosis
Treatment & Medication: Actinomycosis
Follow-up: Actinomycosis
Multimedia: Actinomycosis
References
Further Reading

References

  1. Robboy SJ, Vickery AL Jr. Tinctorial and morphologic properties distinguishing actinomycosis and nocardiosis. N Engl J Med. Mar 12 1970;282(11):593-6. [Medline].

  2. Acevedo F, Baudrand R, Letelier LM, et al. Actinomycosis: a great pretender. Case reports of unusual presentations and a review of the literature. Int J Infect Dis. Jul 2008;12(4):358-62. [Medline].

  3. Figdor D, Davies J. Cell surface structures of Actinomyces israelii. Aust Dent J. Apr 1997;42(2):125-8. [Medline].

  4. Holmberg K, Nord CE, Wadström T. Serological studies of Actinomyces israelii by crossed immunoelectrophoresis: taxonomic and diagnostic applications. Infect Immun. Aug 1975;12(2):398-403. [Medline].

  5. Lambert FW Jr, Brown JM, Georg LK. Identification of Actinomyces israelii and Actinomyces naeslundii by fluorescent-antibody and agar-gel diffusion techniques. J Bacteriol. Nov 1967;94(5):1287-95. [Medline].

  6. Hall V. Actinomyces--gathering evidence of human colonization and infection. Anaerobe. Feb 2008;14(1):1-7. [Medline].

  7. Karimian F, Feizi S, Nazari R, et al. Delayed-onset Actinomyces keratitis after laser in situ keratomileusis. Cornea. Aug 2008;27(7):843-6. [Medline].

  8. Briscoe D, Edelstein E, Zacharopoulos I, et al. Actinomyces canaliculitis: diagnosis of a masquerading disease. Graefes Arch Clin Exp Ophthalmol. Aug 2004;242(8):682-6. [Medline].

  9. Demant E, Hurwitz JJ. Canaliculitis: review of 12 cases. Can J Ophthalmol. Apr 1980;15(2):73-5. [Medline].

  10. Eloy P, Brandt H, Nollevaux MC, et al. Solid cast-forming actinomycotic canaliculitis: case report. Rhinology. Jun 2004;42(2):103-6. [Medline].

  11. Fulmer NL, Neal JG, Bussard GM, Edlich RF. Lacrimal canaliculitis. Am J Emerg Med. Jul 1999;17(4):385-6. [Medline].

  12. Hussain I, Bonshek RE, Loudon K, et al. Canalicular infection caused by Actinomyces. Eye. 1993;7 (Pt 4):542-4. [Medline].

  13. McKellar MJ, Aburn NS. Cast-forming Actinomyces israelii canaliculitis. Aust N Z J Ophthalmol. Nov 1997;25(4):301-3. [Medline].

  14. Richards WW. Actinomycotic lacrimal canaliculitis. Am J Ophthalmol. Jan 1973;75(1):155-7. [Medline].

  15. Smith RL, Henderson PN. Actinomycotic canaliculitis. Aust J Ophthalmol. Feb 1980;8(1):75-9. [Medline].

  16. Sullivan TJ, Hakin KN, Sathananthan N, et al. Chronic canaliculitis. Aust N Z J Ophthalmol. Nov 1993;21(4):273-4. [Medline].

  17. Takemura M, Yokoi N, Nakamura Y, et al. [Canaliculitis caused by Actinomyces in a case of dry eye with punctal plug occlusion]. Nippon Ganka Gakkai Zasshi. Jul 2002;106(7):416-9. [Medline].

  18. Vécsei VP, Huber-Spitzy V, Arocker-Mettinger E, et al. Canaliculitis: difficulties in diagnosis, differential diagnosis and comparison between conservative and surgical treatment. Ophthalmologica. 1994;208(6):314-7. [Medline].

  19. Marthin JK, Lindegaard J, Prause JU, et al. Lesions of the lacrimal drainage system: a clinicopathological study of 643 biopsy specimens of the lacrimal drainage system in Denmark 1910-1999. Acta Ophthalmol Scand. Feb 2005;83(1):94-9. [Medline].

  20. Perez-Santonja JJ, Campos-Mollo E, Fuentes-Campos E, et al. Actinomyces neuii subspecies anitratus chronic endophthalmitis after cataract surgery. Eur J Ophthalmol. May-Jun 2007;17(3):445-7. [Medline].

  21. Scarano FJ, Ruddat MS, Robinson A. Actinomyces viscosus postoperative endophthalmitis. Diagn Microbiol Infect Dis. Jun 1999;34(2):115-7. [Medline].

  22. Milman T, Mirani N, Gibler T, et al. Actinomyces israelii endogenous endophthalmitis. Br J Ophthalmol. Mar 2008;92(3):427-8. [Medline].

  23. Dhaliwal U, Arora VK, Singh N, et al. Clinical and cytopathologic correlation in chronic inflammations of the orbit and ocular adnexa: a review of 55 cases. Orbit. Dec 2004;23(4):219-25. [Medline].

  24. Leigh RJ, Good EF, Rudy RP. Ophthalmoplegia due to actinomycosis. J Clin Neuroophthalmol. Sep 1986;6(3):157-9. [Medline].

  25. Pagliani L, Campi L, Cavallini GM. Orbital actinomycosis associated with painful ophthalmoplegia. Actinomycosis of the orbit. Ophthalmologica. 2006;220(3):201-5. [Medline].

  26. Sullivan TJ, Aylward GW, Wright JE. Actinomycosis of the orbit. Br J Ophthalmol. Aug 1992;76(8):505-6. [Medline].

  27. Huerva V, Espinet R, Galindo C. Recurrent orbital inflammation and Whipple disease. Ocul Immunol Inflamm. Jan-Feb 2008;16(1):37-9. [Medline].

  28. Stupp T, Pavlidis M, Busse H, et al. Presurgical and postsurgical ultrasound assessment of lacrimal drainage dysfunction. Am J Ophthalmol. Nov 2004;138(5):764-71. [Medline].

  29. Tost F, Bruder R, Clemens S. [20-MHz ultrasound of pre-saccular lacrimal ducts]. Ophthalmologe. Jan 2002;99(1):25-8. [Medline].

  30. Tost F, Bruder R, Clemens S. Clinical diagnosis of chronic canaliculitis by 20-MHz ultrasound. Ophthalmologica. 2000;214(6):433-6. [Medline].

  31. Tost F, Bruder R, Ostendorf M. [High-frequency ultrasonography applied to disorders of the lacrimal canaliculi (Part 2)]. J Fr Ophtalmol. Dec 2003;26(10):1035-8. [Medline].

  32. Barnard D, Davies J, Figdor D. Susceptibility of Actinomyces israelii to antibiotics, sodium hypochlorite and calcium hydroxide. Int Endod J. Sep 1996;29(5):320-6. [Medline].

  33. Martin MV. The use of oral amoxycillin for the treatment of actinomycosis. A clinical and in vitro study. Br Dent J. Apr 7 1984;156(7):252-4. [Medline].

  34. Mohr JA, Rhoades ER, Muchmore HG. Actinomycosis treated with lincomycin. JAMA. Jun 29 1970;212(13):2260-2. [Medline].

  35. Zimmerman TJ, et al, eds. Textbook of Ocular Pharmacology. Philadelphia: Lippincott-Raven; 1997.

  36. Shauly Y, Nachum Z, Gdal-On M, et al. Adjunctive hyperbaric oxygen therapy for actinomycotic lacrimal canaliculitis. Graefes Arch Clin Exp Ophthalmol. Jul 1993;231(7):429-31. [Medline].

  37. Georg LK, Coleman RM, Brown JM. Evaluation of an agar precipitin test for the serodiagnosis of actinomycosis. J Immunol. Jun 1968;100(6):1288-92. [Medline].

  38. Khan A, Lightman S. The eye in gastrointestinal disease. Hosp Med. Sep 2003;64(9):548-51. [Medline].

  39. Lee AG. Ocular whipple's disease. Ophthalmology. Nov 2002;109(11):1952-3; author reply 1953. [Medline].

  40. Medical Economics. Physicians' Desk Reference. NJ: Medical Economics Press; 1999.

  41. Shah JK. Actinomycosis: a ten year review. East Afr Med J. Sep 1971;48(9):496-501. [Medline].

  42. Weinberg RJ, Sartoris MJ, Buerger GF Jr, et al. Fusobacterium in presumed Actinomyces canaliculitis. Am J Ophthalmol. Sep 1977;84(3):371-4. [Medline].

Further Reading

Polenakovik H. Actinomycosis. eMedicine Journal [serial online]. April 14, 2006; Available at: http://www.emedicine.com/Med/topic31.htm.

Keywords

actinomycosis, Actinomycetales, Actinomycetaceae, Actinomycetes, Actinomyces, Actinomyces israelii, A israelii, keratoactinomycosis, keratitis, canaliculitis, anaerobic bacillus, Actinomyces gerencseriae, Actinomyces naeslundii, Actinomyces odontolyticus, Actinomyces viscosus, Actinomyces turicensis, Actinomyces meyeri, Propionibacterium propionicus, Actinobacillus actinomycetemcomitans, Prevotella, Fusobacterium, Bacteroides, Staphylococcus, Streptococcus, Enterobacteriaceae, actinophytosis

Contributor Information and Disclosures

Author

Manolette R Roque, MD, MBA, President and CEO, Service Chief of Ocular Immunology and Uveitis, Refractive Surgery, EYE REPUBLIC Ophthalmology Clinic; General Manager, Ophthalmic Consultants Philippines; Section Chief of Ocular Immunology and Uveitis, Department of Ophthalmology, Asian Hospital and Medical Center; Section Chief of Ocular Immunology and Uveitis, Department of Ophthalmology, St. Luke's Medical Center Global City; Senior Eye Surgeon, The LASIK Surgery Clinic
Manolette R Roque, MD, MBA is a member of the following medical societies: American Academy of Ophthalmic Executives, American Academy of Ophthalmology, American Society of Cataract and Refractive Surgery, American Society of Ophthalmic Administrators, American Uveitis Society, International Ocular Inflammation Society, Philippine Medical Association, Philippine Ocular Inflammation Society, and Philippine Society of Cataract and Refractive Surgery
Disclosure: Nothing to disclose.

Coauthor(s)

Barbara L Roque, MD, Full Partner, Ophthalmic Consultants Philippines Co, Chief of Service, Pediatric Ophthalmology and Strabismus, Consulting Staff, Orbit and Eye Plastics, Eye Republic Ophthalmology Clinic
Disclosure: Nothing to disclose.

C Stephen Foster, MD, FACS, FACR, FAAO, Clinical Professor of Ophthalmology, Harvard Medical School; Consulting Staff, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary; Founder and President, Ocular Immunology and Uveitis Foundation, Massachusetts Eye Research and Surgery Institution
C Stephen Foster, MD, FACS, FACR, FAAO is a member of the following medical societies: Alpha Omega Alpha, American Academy of Ophthalmology, American Association of Immunologists, American College of Rheumatology, American College of Surgeons, American Federation for Clinical Research, American Medical Association, American Society for Microbiology, American Uveitis Society, Association for Research in Vision and Ophthalmology, Massachusetts Medical Society, Royal Society of Medicine, and Sigma Xi
Disclosure: Nothing to disclose.

Medical Editor

Jorge G Camara, MD, Professor of Ophthalmology, Department of Surgery and Director of Fellowship Training Program in Ophthalmic Plastic and Reconstructive Surgery for Countries Served by the Aloha Medical Mission, University of Hawaii John A Burns School of Medicine
Jorge G Camara, MD is a member of the following medical societies: American Academy of Ophthalmology, American Medical Association, and American Society of Ophthalmic Plastic and Reconstructive Surgery
Disclosure: Nothing to disclose.

Pharmacy Editor

Simon K Law, MD, PharmD, Assistant Professor of Ophthalmology, Jules Stein Eye Institute; Chief of Section of Ophthalmology Surgical Services, Department of Veterans Affairs Healthcare Center, West Los Angeles
Simon K Law, MD, PharmD is a member of the following medical societies: American Academy of Ophthalmology, American Glaucoma Society, and Association for Research in Vision and Ophthalmology
Disclosure: Nothing to disclose.

Managing Editor

Mark T Duffy, MD, PhD, Consulting Staff, Division of Oculoplastic, Orbito-facial, Lacrimal and Reconstructive Surgery, Green Bay Eye Clinic, BayCare Clinic; Medical Director, Advanced Cosmetic Solutions, A BayCare Clinic
Mark T Duffy, MD, PhD is a member of the following medical societies: American Academy of Ophthalmology, American Medical Association, American Society of Ophthalmic Plastic and Reconstructive Surgery, Sigma Xi, and Society for Neuroscience
Disclosure: Allergan - Botox Cosmetic Consulting fee Consulting; Quest medical - lacrimal balloons Honoraria Speaking and teaching; Ortho-Neutrogenia Consulting fee Consulting

CME Editor

Lance L Brown, OD, MD, Ophthalmologist, Affiliated With Freeman Hospital and St John's Hospital, Regional Eye Center, Joplin, Missouri
Disclosure: Nothing to disclose.

Chief Editor

Hampton Roy Sr, MD, Associate Clinical Professor, Department of Ophthalmology, University of Arkansas for Medical Sciences
Hampton Roy Sr, MD is a member of the following medical societies: American Academy of Ophthalmology, American College of Surgeons, and Pan-American Association of Ophthalmology
Disclosure: Nothing to disclose.

 
 
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