eMedicine Specialties > Endocrinology > Thyroid

Goiter, Toxic Nodular: Multimedia

Author: Anu Bhalla Davis, MD, Assistant Professor, Department of Internal Medicine, Division of Diabetes, Endocrinology, and Metabolism, University of Texas Health Science Center at Houston
Coauthor(s): Philip R Orlander, MD, Interim Chair of Medicine, Director of Endocrinology and Metabolism Fellowship, Director and Professor, Department of Medicine, Division of Endocrinology, University of Texas Health Science Center at Houston; Asra Kermani, MBBS, Postdoctoral Fellow, Center for Human Nutrition, University of Texas Southwestern Medical School
Contributor Information and Disclosures

Updated: Jun 4, 2009

Multimedia

Patchy uptake of iodine (<SUP><FONT size=-1>123</...Media file 1: Patchy uptake of iodine (123I) in a toxic multinodular goiter.
Patchy uptake of iodine (<SUP><FONT size=-1>123</...

Patchy uptake of iodine (123I) in a toxic multinodular goiter.

More on Goiter, Toxic Nodular

Overview: Goiter, Toxic Nodular
Differential Diagnoses & Workup: Goiter, Toxic Nodular
Treatment & Medication: Goiter, Toxic Nodular
Follow-up: Goiter, Toxic Nodular
Multimedia: Goiter, Toxic Nodular
References
Further Reading

References

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  28. Holzapfel HP, Fuhrer D, Wonerow P, et al. Identification of constitutively activating somatic thyrotropin receptor mutations in a subset of toxic multinodular goiters. J Clin Endocrinol Metab. Dec 1997;82(12):4229-33. [Medline][Full Text].

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  30. Koornstra JJ, Kerstens MN, Hoving J, et al. Clinical and biochemical changes following 131I therapy for hyperthyroidism in patients not pretreated with antithyroid drugs. Neth J Med. Nov 1999;55(5):215-21. [Medline].

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  34. Maussier ML, D'Errico G, Putignano P, et al. Thyrotoxicosis: clinical and laboratory assessment. Rays. Apr-Jun 1999;24(2):263-72. [Medline].

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  37. Sato K, Miyakawa M, Eto M, et al. Clinical characteristics of amiodarone-induced thyrotoxicosis and hypothyroidism in Japan. Endocr J. Jun 1999;46(3):443-51. [Medline].

  38. Siegel RD, Lee SL. Toxic nodular goiter. Toxic adenoma and toxic multinodular goiter. Endocrinol Metab Clin North Am. Mar 1998;27(1):151-68. [Medline].

  39. Talbot JN, Duron F, Piketty ML, et al. Low thyrotropin (TSH) levels in goiter. Relationship with scintigraphic findings and other biological parameters. Thyroidology. Apr 1989;1(1):39-44. [Medline].

  40. Tonacchera M, Chiovato L, Pinchera A, et al. Hyperfunctioning thyroid nodules in toxic multinodular goiter share activating thyrotropin receptor mutations with solitary toxic adenoma. J Clin Endocrinol Metab. Feb 1998;83(2):492-8. [Medline][Full Text].

  41. Tonacchera M, Vitti P, Agretti P, et al. Activating thyrotropin receptor mutations in histologically heterogeneous hyperfunctioning nodules of multinodular goiter. Thyroid. Jul 1998;8(7):559-64. [Medline].

Further Reading

Related eMedicine topics:
Hyperthyroidism [Endocrinology]
Hyperthyroidism [Pediatrics: General Medicine]
Hyperthyroidism, Thyroid Storm, and Graves Disease
Hypothyroidism [Endocrinology]
Hypothyroidism [Pediatrics: General Medicine]
Iodine Deficiency
Thyroid Dysfunction Induced by Amiodarone Therapy

Keywords

toxic nodular goiter, goiter, TNG, toxic multinodular goiter, hyperthyroidism, hyperthyroid, Plummer disease, Plummer's disease, toxic uninodular goiter, autonomously functioning thyroid nodule, toxic adenoma, Graves disease, Graves' disease, iodine deficiency, Jod-Basedow phenomenon, Jod-Basedow effect, Jod-Basedow's effect, hyperfunctioning nodule, multinodular thyroid, underlying nontoxic multinodular goiter, amiodarone, amiodarone-induced hyperthyroidism, thyrotoxicosis, apathetic hyperthyroidism, suppressed thyroid-stimulating hormone, TSH, TSH receptors, superior vena cava syndrome, hyperplasia, cyclic adenosine monophosphate, cAMP, thyroxine, T4, iodine-induced hyperthyroidism, triiodothyronine, T3, micronodular growth patterns, follicles, D727E, endothelin-1, ET-1

Contributor Information and Disclosures

Author

Anu Bhalla Davis, MD, Assistant Professor, Department of Internal Medicine, Division of Diabetes, Endocrinology, and Metabolism, University of Texas Health Science Center at Houston
Disclosure: Nothing to disclose.

Coauthor(s)

Philip R Orlander, MD, Interim Chair of Medicine, Director of Endocrinology and Metabolism Fellowship, Director and Professor, Department of Medicine, Division of Endocrinology, University of Texas Health Science Center at Houston
Philip R Orlander, MD is a member of the following medical societies: American Association of Clinical Endocrinologists, American Diabetes Association, Endocrine Society, and Texas Medical Association
Disclosure: Nothing to disclose.

Asra Kermani, MBBS, Postdoctoral Fellow, Center for Human Nutrition, University of Texas Southwestern Medical School
Asra Kermani, MBBS is a member of the following medical societies: American College of Physicians-American Society of Internal Medicine
Disclosure: Nothing to disclose.

Medical Editor

Robert A Gabbay, MD, PhD, Associate Professor of Medicine, Division of Endocrinology, Diabetes and Metabolism, Laurence M Demers Career Development Professor, Penn State College of Medicine; Director, Diabetes Program, Penn State Milton S Hershey Medical Center; Executive Director, Penn State Institute for Diabetes and Obesity
Robert A Gabbay, MD, PhD is a member of the following medical societies: American Association of Clinical Endocrinologists, American Diabetes Association, and Endocrine Society
Disclosure: Novo Nordisk Honoraria Speaking and teaching; Merck Honoraria Speaking and teaching

Pharmacy Editor

Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine
Disclosure: Nothing to disclose.

Managing Editor

Kent Wehmeier, MD, Professor, Department of Internal Medicine, Division of Endocrinology, Diabetes, and Metabolism, St Louis University School of Medicine
Kent Wehmeier, MD is a member of the following medical societies: American Society of Hypertension, Endocrine Society, and International Society for Clinical Densitometry
Disclosure: Nothing to disclose.

CME Editor

Mark Cooper, MBBS, PhD, FRACP, Head, Diabetes & Metabolism Division, Baker Heart Research Institute, Professor of Medicine, Monash University
Disclosure: Nothing to disclose.

Chief Editor

George T Griffing, MD, Professor of Medicine, St Louis University School of Medicine
George T Griffing, MD is a member of the following medical societies: American Association for the Advancement of Science, American College of Medical Practice Executives, American College of Physician Executives, American College of Physicians, American Diabetes Association, American Federation for Medical Research, American Heart Association, Central Society for Clinical Research, Endocrine Society, International Society for Clinical Densitometry, and Southern Society for Clinical Investigation
Disclosure: Nothing to disclose.

 
 
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