Posner-Schlossman Syndrome Workup

  • Author: James H Oakman Jr, MD; Chief Editor: Hampton Roy Sr, MD   more...
 
Updated: Mar 2, 2012
 

Imaging Studies

Digital infrared iris photography may yield informative image patterns.[28]

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Procedures

Perform gonioscopy to rule out closed-angle glaucoma.

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Histologic Findings

Microscopic examination of trabeculectomy specimens taken at the time of an acute attack reveals inflammation with an abundant mononuclear cell infiltration of the trabecular meshwork. The keratic precipitates associated with PSS have been shown by specular microscopy to differ in morphology from other nongranulomatous fresh keratic precipitates in that they cluster with pseudopods extending between them.

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Contributor Information and Disclosures
Author

James H Oakman Jr, MD  Partner, Southern Eye Center, Augusta, Georgia

James H Oakman Jr, MD is a member of the following medical societies: American Academy of Ophthalmology, American Society of Cataract and Refractive Surgery, Association of American Physicians and Surgeons, Georgia Medical Society, Georgia Society of General Surgeons, and Georgia Society of Ophthalmology

Disclosure: Nothing to disclose.

Specialty Editor Board

Andrew I Rabinowitz, MD  Consulting Staff, Department of Ophthalmology, Barnet Dulaney Perkins Eye Center

Andrew I Rabinowitz, MD is a member of the following medical societies: Aerospace Medical Association, American Academy of Ophthalmology, and American Medical Association

Disclosure: Nothing to disclose.

Simon K Law, MD, PharmD  Associate Professor of Ophthalmology, Jules Stein Eye Institute, University of California, Los Angeles, David Geffen School of Medicine

Simon K Law, MD, PharmD is a member of the following medical societies: American Academy of Ophthalmology, American Glaucoma Society, and Association for Research in Vision and Ophthalmology

Disclosure: Nothing to disclose.

Martin B Wax, MD  Clinical Professor, Department of Ophthalmology, University of Texas Southwestern Medical School; Vice President, Ophthalmology Research and Development, Head, Ophthalmology Discovery Research, Alcon Labs, Inc

Martin B Wax, MD is a member of the following medical societies: American Academy of Ophthalmology, American Glaucoma Society, and Society for Neuroscience

Disclosure: Nothing to disclose.

Lance L Brown, OD, MD  Ophthalmologist, Affiliated With Freeman Hospital and St John's Hospital, Regional Eye Center, Joplin, Missouri

Disclosure: Nothing to disclose.

Chief Editor

Hampton Roy Sr, MD  Associate Clinical Professor, Department of Ophthalmology, University of Arkansas for Medical Sciences

Hampton Roy Sr, MD is a member of the following medical societies: American Academy of Ophthalmology, American College of Surgeons, and Pan-American Association of Ophthalmology

Disclosure: Nothing to disclose.

References
  1. Posner A, Schlossman A. Syndrome of unilateral recurrent attacks of glaucoma with cyclitic symptoms. Arch Ophthalmol. 1948;39:517.

  2. Posner A, Schlossman A. Further observations on the syndrome of glaucomatocyclitic crisis. Trans Am Acad Ophthalmol Otolaryngol. 1953;57:531.

  3. Theodore FH. Observations on glaucomatocyclitic crisis. Br J Ophthalmol. 1952;36:207.

  4. Kass MA, Becker B, Kolker AE. Glaucomatocyclitic crisis and primary open-angle glaucoma. Am J Ophthalmol. Apr 1973;75(4):668-73. [Medline].

  5. Levatin P. Glaucomatocyclitic crisis occurring in both eyes. Am J Ophthalmol. 1956;41:1056.

  6. Dinakaran S, Kayarkar V. Trabeculectomy in the management of Posner-Schlossman syndrome. Ophthalmic Surg Lasers. Jul-Aug 2002;33(4):321-2. [Medline].

  7. Maeda H, Nakamura M, Negi A. Selective reduction of the S-cone component of the electroretinogram in Posner-Schlossman syndrome. Eye. Apr 2001;15:163-7. [Medline].

  8. Paivonsalo-Hietanen T, Tuominen J, Vaahtoranta-Lehtonen H, et al. Incidence and prevalence of different uveitis entities in Finland. Acta Ophthalmol Scand. Feb 1997;75(1):76-81. [Medline].

  9. Darchuk V, Sampaolesi J, Mato L, et al. Optic nerve head behavior in Posner-Schlossman syndrome. Int Ophthalmol. 2001;23(4-6):373-9. [Medline].

  10. Burnstein Y, Shelton K, Higginbotham EJ. Glaucomatocyclitic crisis in a child. Am J Ophthalmol. Jul 1998;126(1):136-7. [Medline].

  11. Pillai CT, Dua HS, Azuara-Blanco A, et al. Evaluation of corneal endothelium and keratic precipitates by specular microscopy in anterior uveitis. Br J Ophthalmol. Dec 2000;84(12):1367-71. [Medline].

  12. Takusagawa HL, Liu Y, Wiggs JL. Infectious theories of Posner-Schlossman syndrome. Int Ophthalmol Clin. Fall 2011;51(4):105-15. [Medline].

  13. Bloch-Michel E, Dussaix E, Cerqueti P, et al. Possible role of cytomegalovirus infection in the etiology of the Posner-Schlossmann syndrome. Int Ophthalmol. Dec 1987;11(2):95-6. [Medline].

  14. Teoh SB, Thean L, Koay E. Cytomegalovirus in aetiology of Posner-Schlossman syndrome: evidence from quantitative polymerase chain reaction. Eye. Dec 2005;19(12):1338-40. [Medline].

  15. Chee SP, Bacsal K, Jap A, Se-Thoe SY, Cheng CL, Tan BH. Clinical features of cytomegalovirus anterior uveitis in immunocompetent patients. Am J Ophthalmol. May 2008;145(5):834-40. [Medline].

  16. Yang SY, Chen MJ, Chen KH, Li AF, Chou CK, Lee SM. Cytomegalovirus and herpes simplex virus as causes of bilateral anterior uveitis in an immunocompetent patient. J Chin Med Assoc. Jan 2011;74(1):48-50. [Medline].

  17. Yamamoto S, Pavan-Langston D, Tada R, et al. Possible role of herpes simplex virus in the origin of Posner-Schlossman syndrome. Am J Ophthalmol. Jun 1995;119(6):796-8. [Medline].

  18. Choi CY, Kim MS, Kim JM, Park SH, Park KH, Hong C. Association between Helicobacter pylori infection and Posner-Schlossman syndrome. Eye (Lond). Jan 2010;24(1):64-9. [Medline].

  19. Nagataki S, Mishima J. Aqueous humor dynamics in glaucomatocyclitic crisis. Invest Ophthalmol. 1976;15:365.

  20. Masuda K, Izawa Y, Mishima S. Prostaglandins and glaucomatocyclitic crisis. Jpn J Ophthalmol. 1975;19:368.

  21. Neufeld AH, Sears ML. Prostaglandin and eye. Prostaglandins. Aug 1973;4(2):157-75. [Medline].

  22. Eakins KE. Increased intraocular pressure produced by prostaglandins E1 and E2 in the cat eye. Exp Eye Res. Jul 1970;10(1):87-92. [Medline].

  23. Jap A, Sivakumar M, Chee SP. Is Posner Schlossman syndrome benign?. Ophthalmology. May 2001;108(5):913-8. [Medline].

  24. Hirose S, Ohno S, Matsuda H. HLA-Bw54 and glaucomatocyclitic crisis. Arch Ophthalmol. Dec 1985;103(12):1837-9. [Medline].

  25. Knox DL. Glaucomatocyclitic crises and systemic disease: peptic ulcer, other gastrointestinal disorders, allergy and stress. Trans Am Ophthalmol Soc. 1988;86:473-95. [Medline].

  26. Kim R, Van Stavern G, Juzych M. Nonarteritic anterior ischemic optic neuropathy associated with acute glaucoma secondary to Posner-Schlossman syndrome. Arch Ophthalmol. Jan 2003;121(1):127-8. [Medline].

  27. Irak I, Katz BJ, Zabriskie NA, et al. Posner-Schlossman syndrome and nonarteritic anterior ischemic optic neuropathy. J Neuroophthalmol. Dec 2003;23(4):264-7. [Medline].

  28. Roberts DK, Lukic AS, Yang Y, Moroi SE, Wilensky JT, Wernick MN. Novel observations and potential applications using digital infrared iris imaging. Ophthalmic Surg Lasers Imaging. Mar-Apr 2009;40(2):207-16. [Medline].

  29. Hung PT, Chang JM. Treatment of glaucomatocyclitic crises. Am J Ophthalmol. Feb 1974;77(2):169-72. [Medline].

  30. Varma R, Katz LJ, Spaeth GL. Surgical treatment of acute glaucomatocyclitic crisis in a patient with primary open-angle glaucoma. Am J Ophthalmol. Jan 15 1988;105(1):99-100. [Medline].

  31. Wong PC, Ruderman JM, Krupin T, et al. 5-Fluorouracil after primary combined filtration surgery. Am J Ophthalmol. Feb 15 1994;117(2):149-54. [Medline].

  32. Albert DM, Jakobiec FA. Principles and Practice of Ophthalmology. Vol 3. Philadelphia: Saunders; 1994:1426-35.

  33. de Roetth A Jr. Glaucomatocyclitic crisis. Am J Ophthalmol. Mar 1970;69(3):370-1. [Medline].

  34. Fiore PM. Inflammatory glaucoma. In: Albert DM, Jakobiec FA, eds. Principles and Practice of Ophthalmology. Vol 3. 1994:1426-35.

  35. Grant WM. Clinical measurements of aqueous outflow. Arch Ophthalmol. 1951;46:113.

  36. Hahn IH, Stillman MC. A case of glaucomatocyclitic crisis in the emergency department. Ann Emerg Med. Feb 2006;47(2):167-9. [Medline].

  37. Harstad HK, Ringvold A. Glaucomatocyclitic crises (Posner-Schlossman syndrome). A case report. Acta Ophthalmol (Copenh). Apr 1986;64(2):146-51. [Medline].

  38. Hart CT, Weatherill JR. Gonioscopy and tonography in glaucomatocyclitic crises. Br J Ophthalmol. Sep 1968;52(9):682-7. [Medline].

  39. Hollowich F. Clinical aspects and therapy of the Posner-Schlossman syndrome. Klin Monatsbl Augenheilkd. 1978;172:336.

  40. Hoskins HD, Kass MA. Secondary open-angle glaucoma. Diagnosis and therapy of the glaucomas. 1989;332-4.

  41. Krupin T, Feitl ME. Glaucoma associated with uveitis. In: The Glaucomas. 1989:1205-23.

  42. Perdviel G, Raynaud G, Gayard M. Syndrome de Posner-Schlossman et glaucoma. Bull Soc Ophthalmol Fr. 1962;62:611.

  43. Raitta C, Klemetti A. Steroidbelastung bei Posner-Schlossmanschem Syndrom. V Graefes Arch Klin Exp Ophthalmol. 1967;174:66.

  44. Rhee DJ, Rapuano CJ, Belzer TL, et al. Physician Desk Reference for Ophthalmic Medicines. 2006.

  45. Riatta C, Vannas A. Glaucomatocyclitic crisis. Arch Ophthalmol. 1977;95:608.

  46. Richardson K. Acute glaucoma after trauma. In: Freeman HM, ed. Ocular Trauma. New York: Appleton-Century-Crofts; 1979.

  47. Ritch R, Shields MB, Krupin T. The Glaucomas. St. Louis: Mosby; 1989:1205-23.

  48. Shields MB. Glaucomas associated with ocular inflammation. In: Textbook of Glaucoma. 1992:356-61.

  49. Spivey BE, Armaly MF. Tonographic findings in glaucomatocyclitic crisis. Am J Ophthalmol. 1963;55:47.

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