Ectopia Lentis Workup

  • Author: Charles W Eifrig, MD; Chief Editor: Hampton Roy Sr, MD   more...
 
Updated: Jul 22, 2011
 

Laboratory Studies

Perform appropriate diagnostic and laboratory evaluation, if a hereditary condition is suspected (eg, cardiac evaluation for Marfan syndrome, check serum and urine levels of homocysteine or methionine for homocystinuria).

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Imaging Studies

Echography: Axial length measurement may be of benefit (patients with Marfan syndrome have large globes).

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Proceed to Treatment & Management
 
 
Contributor Information and Disclosures
Author

Charles W Eifrig, MD  Vitreoretinal Surgeon, Retina Associates of Orange County

Charles W Eifrig, MD is a member of the following medical societies: American Academy of Ophthalmology, American College of Surgeons, American Society of Retina Specialists, and Retina Society

Disclosure: Nothing to disclose.

Specialty Editor Board

Richard W Allinson, MD  Associate Professor, Department of Ophthalmology, Texas A&M University Health Science Center; Senior Staff Ophthalmologist, Scott and White Clinic

Richard W Allinson, MD, is a member of the following medical societies: American Academy of Ophthalmology, American Medical Association, and Texas Medical Association

Disclosure: Nothing to disclose.

Simon K Law, MD, PharmD  Associate Professor of Ophthalmology, Jules Stein Eye Institute, University of California, Los Angeles, David Geffen School of Medicine

Simon K Law, MD, PharmD is a member of the following medical societies: American Academy of Ophthalmology, American Glaucoma Society, and Association for Research in Vision and Ophthalmology

Disclosure: Nothing to disclose.

J James Rowsey, MD  Former Director of Corneal Services, St Luke's Cataract and Laser Institute

J James Rowsey, MD is a member of the following medical societies: American Academy of Ophthalmology, American Association for the Advancement of Science, American Medical Association, Association for Research in Vision and Ophthalmology, Florida Medical Association, Pan-American Association of Ophthalmology, Sigma Xi, and Southern Medical Association

Disclosure: Nothing to disclose.

Lance L Brown, OD, MD  Ophthalmologist, Affiliated With Freeman Hospital and St John's Hospital, Regional Eye Center, Joplin, Missouri

Disclosure: Nothing to disclose.

Chief Editor

Hampton Roy Sr, MD  Associate Clinical Professor, Department of Ophthalmology, University of Arkansas for Medical Sciences

Hampton Roy Sr, MD is a member of the following medical societies: American Academy of Ophthalmology, American College of Surgeons, and Pan-American Association of Ophthalmology

Disclosure: Nothing to disclose.

Acknowledgments

The authors and editors of eMedicine gratefully acknowledge the contributions of previous coauthor, David E Eifrig, MD, to the development and writing of this article.

References

  1. Jarrett WH II. Dislocation of the lens. A study of 166 hospitalized cases. Arch Ophthalmol. Sep 1967;78(3):289-96. [Medline].

  2. Nirankari MS, Chaddah MR. Displaced lens. Am J Ophthalmol. Jun 1967;63(6):1719-23. [Medline].

  3. Nelson LB, Maumenee IH. Ectopia lentis. Surv Ophthalmol. Nov-Dec 1982;27(3):143-60. [Medline].

  4. Clark CC. Ectopia lentis: a pathologic and clinical study. Arch Ophthalmol. 1939;21:124-153.

  5. Albert DM, Jakobiec FA. Pathology of the lens. In: Principles and Practice of Ophthalmology. 2000:2225-2239.

  6. Nelson L. Ectopia lentis in childhood. J Pediatr Ophthalmol Strabismus. Jan-Feb 2008;45(1):12. [Medline].

  7. Omulecki W, Wilczynski M, Gerkowicz M. Management of bilateral ectopia lentis et pupillae syndrome. Ophthalmic Surg Lasers Imaging. Jan-Feb 2006;37(1):68-71. [Medline].

  8. Parrish RK II. Anatomy, physiology, and pathology of the crystalline lens. In: Bascom Palmer Eye Institute's Atlas of Ophthalmology. 1999:241.

  9. Duane T. Cataracts and systemic disease. In: Duane's Clinical Ophthalmology. 5. 1999:13-14.

  10. Ganesh A, Smith C, Chan W, et al. Immunohistochemical evaluation of conjunctival fibrillin-1 in Marfan syndrome. Arch Ophthalmol. Feb 2006;124(2):205-9. [Medline].

  11. Wentzloff JN, Kaldawy RM, Chen TC. Weill-Marchesani syndrome. J Pediatr Ophthalmol Strabismus. May-Jun 2006;43(3):192. [Medline].

  12. Konradsen T, Kugelberg M, Zetterström C. Visual outcomes and complications in surgery for ectopia lentis in children. J Cataract Refract Surg. May 2007;33(5):819-24. [Medline].

 
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Ectopia lentis. Dislocated traumatic lens (cataract).
Ectopia lentis. Dislocated lens into the vitreous secondary to trauma.
Ectopia lentis. Supertemporal dislocation of a lens in the right eye of a patient with Marfan syndrome. Note the attached zonular fibers.
Ectopia lentis. Microspherophakia and spontaneous inferior dislocation of a lens in a patient with Weil-Marchesani syndrome.
 
 
 
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