eMedicine Specialties > Ophthalmology > Lid

Entropion

Author: Christopher DeBacker, MD, Volunteer Faculty, Department of Ophthalmology, California Pacific Medical Center; Consulting Staff, Ophthalmic Medical Associates
Coauthor(s): Robert M Dryden, MD, FACS, Clinical Professor, Department of Ophthalmology, University of Arizona School of Medicine
Contributor Information and Disclosures

Updated: Nov 10, 2006

Introduction

Background

Entropion is a malposition resulting in inversion of the eyelid margin. The morbidity of the condition is a result of ocular surface irritation and damage. Successful management of this condition depends on appropriate classification and a procedural choice that adequately addresses the underlying abnormality.

Pathophysiology

The pathophysiology depends on the type of entropion seen and is discussed below.

Mortality/Morbidity

The primary morbidity is ocular surface irritation. Corneal abrasions and scars can occur.

Sex

No sexual predilection exists.

Age

Although all ages can be affected, this entity is seen primarily in older adults.

Clinical

History

The first order of business when assessing the patient with entropion is to determine the etiology and place it into an appropriate classification.

Physical

  • Congenital entropion
    • Dysgenesis of the lower eyelid retractors may be present creating instability in the eyelid with consequent entropion, or a paucity of tissue may be present vertically in the posterior lamella of the eyelid.
    • Structural defects in the tarsal plate also may result in a tarsal kink syndrome, with entropion in the upper eyelid.
  • Acute spastic entropion
    • Spastic closure of the eyelids allows the orbicularis oculi muscle to overwhelm the oppositional action of the lower eyelid retractors, resulting in an inturning of the eyelid margin and further irritation of the ocular surface from the inturned eyelashes.
    • Most of these patients often have an involutional component as well.
  • Involutional entropion
  • The patient may exhibit horizontal laxity of the medial and/or lateral canthal tendons.
  • The snap test is a useful diagnostic maneuver. The eyelid margin is pulled away from the globe, with poor resultant snap back to the globe surface. Make sure the patient does not blink the lid back.
  • Patients usually have an involution of the posterior eyelid retractors, with the eyelid inturning in much the same manner as with spastic entropion.
  • Involution of the soft tissues of the orbit, particularly the orbital fat, may lead to involutional enophthalmos, which in turn can lead to unstable eyelid position with entropion.
  • Cicatricial entropion
  • These patients usually will display scar tissue of the conjunctiva, usually a result of trauma, chemical burns, Stevens-Johnson syndrome, ocular cicatricial pemphigoid (OCP), infections, or local response to topical medication.
  • Digital eversion of the eyelid margin is difficult in cases of cicatricial entropion, whereas it is quite easy in cases of involutional entropion.
  • Examination of the tarsus and palpebral conjunctiva usually will point to the diagnosis in these cases.

Causes

Entropion can be divided into the following classes: congenital, acute spastic, involutional, and cicatricial.

  • The congenital form of entropion is very rare. It may arise due to a number of underlying developmental abnormalities, usually in the lower eyelid.
  • Acute spastic entropion usually occurs as a result of ocular irritation, which may be due to infectious, inflammatory, or traumatic (eg, surgical) processes.
  • Involutional entropion usually is due to a constellation of problems.
  • Cicatricial entropion occurs as a result of scarification of the palpebral conjunctiva, with consequent inward rotation of the eyelid margin.
  • Other diagnostic considerations
    • Entropion must be distinguished from a number of other conditions that may simulate entropion.
    • Epiblepharon is a congenital condition in which the pretarsal orbicularis muscle and the skin covering the eyelid override the eyelid margin and push the eyelashes vertically or inwards.
      • The eyelid margin in these cases actually is in a normal position.
      • This condition most commonly is seen in the lower eyelids and is more common in Asians.
      • Compared to congenital entropion, epiblepharon usually resolves spontaneously as the face matures.
    • Eyelid retraction also may simulate entropion in both the upper and lower eyelids. However, the eyelid margins in these cases display a normal apposition to the globe.
    • Trichiasis and distichiasis are conditions in which misdirected eyelashes are directed toward the globe. While trichiasis may coexist with entropion, particularly in cicatricial cases, it is a distinct entity and requires its own treatment approach.

More on Entropion

Overview: Entropion
Differential Diagnoses & Workup: Entropion
Treatment & Medication: Entropion
Follow-up: Entropion
Multimedia: Entropion
References

References

  1. Bartley GB, Kay PP. Posterior lamellar eyelid reconstruction with a hard palate mucosal graft. Am J Ophthalmol. Jun 15 1989;107(6):609-12. [Medline].

  2. Cheung D, Sandramouli S. Consecutive ectropion after the Wies procedure. Ophthal Plast Reconstr Surg. Jan 2004;20(1):64-8. [Medline].

  3. Christiansen G, Mohney BG, Baratz KH, Bradley EA. Botulinum toxin for the treatment of congenital entropion. Am J Ophthalmol. Jul 2004;138(1):153-5. [Medline].

  4. Dortzbach RK, McGetrick JJ. Involutional entropion of the lower eyelid. Ophthalmic Plast Reconstr Surg. 1983;2:257-267.

  5. Ho SF, Pherwani A, Elsherbiny SM, Reuser T. Lateral tarsal strip and quickert sutures for lower eyelid entropion. Ophthal Plast Reconstr Surg. Sep 2005;21(5):345-8. [Medline].

  6. Khan SJ, Meyer DR. Transconjunctival lower eyelid involutional entropion repair: long-term follow-up and efficacy. Ophthalmology. Nov 2002;109(11):2112-7. [Medline].

  7. McCord CD Jr, Chen WP. Tarsal polishing and mucous membrane grafting for cicatricial entropion, trichiasis and epidermalization. Ophthalmic Surg. Dec 1983;14(12):1021-5. [Medline].

  8. Millman AL, Katzen LB, Putterman AM. Cicatricial entropion: an analysis of its treatment with transverse blepharotomy and marginal rotation. Ophthalmic Surg. Aug 1989;20(8):575-9. [Medline].

  9. Quickert MH, Rathbun E. Suture repair of entropion. Arch Ophthalmol. Mar 1971;85(3):304-5. [Medline].

Further Reading

Keywords

involutional entropion, cicatricial entropion, acute spastic entropion, congenital entropion, eyelid entropion, eyelid inversion, eyelid margin inversion, ocular irritation, eyelid retraction, corneal abrasions

Contributor Information and Disclosures

Author

Christopher DeBacker, MD, Volunteer Faculty, Department of Ophthalmology, California Pacific Medical Center; Consulting Staff, Ophthalmic Medical Associates
Christopher DeBacker, MD is a member of the following medical societies: American Academy of Cosmetic Surgery, American Academy of Ophthalmology, American Society of Ophthalmic Plastic and Reconstructive Surgery, and Phi Beta Kappa
Disclosure: Nothing to disclose.

Coauthor(s)

Robert M Dryden, MD, FACS, Clinical Professor, Department of Ophthalmology, University of Arizona School of Medicine
Robert M Dryden, MD, FACS is a member of the following medical societies: Alpha Omega Alpha, American Academy of Cosmetic Surgery, American Academy of Facial Plastic and Reconstructive Surgery, American Academy of Ophthalmology, American College of Surgeons, American Society of Ophthalmic Plastic and Reconstructive Surgery, and Phi Beta Kappa
Disclosure: Nothing to disclose.

Medical Editor

Ron W Pelton, MD, PhD, Consulting Staff, Department of Surgery, Memorial Hospital
Ron W Pelton, MD, PhD is a member of the following medical societies: American Academy of Ophthalmology, American Medical Association, American Society of Ophthalmic Plastic and Reconstructive Surgery, Colorado Medical Society, Utah Medical Association, and Wilderness Medical Society
Disclosure: Nothing to disclose.

Pharmacy Editor

Simon K Law, MD, PharmD, Assistant Professor of Ophthalmology, Jules Stein Eye Institute; Chief of Section of Ophthalmology Surgical Services, Department of Veterans Affairs Healthcare Center, West Los Angeles
Simon K Law, MD, PharmD is a member of the following medical societies: American Academy of Ophthalmology, American Glaucoma Society, and Association for Research in Vision and Ophthalmology
Disclosure: Nothing to disclose.

Managing Editor

Mark T Duffy, MD, PhD, Consulting Staff, Division of Oculoplastic, Orbito-facial, Lacrimal, and Reconstructive Surgery, Green Bay Eye Clinic, BayCare Clinic
Mark T Duffy, MD, PhD is a member of the following medical societies: American Academy of Ophthalmology, American Medical Association, American Society of Ophthalmic Plastic and Reconstructive Surgery, Sigma Xi, and Society for Neuroscience
Disclosure: Allergan - Botox Cosmetic Consulting fee Consulting; Quest medical - lacrimal balloons Honoraria Speaking and teaching

CME Editor

Lance L Brown, OD, MD, Ophthalmologist, Affiliated With Freeman Hospital and St John's Hospital, Regional Eye Center, Joplin, Missouri
Disclosure: Nothing to disclose.

Chief Editor

Hampton Roy Sr, MD, Associate Clinical Professor, Department of Ophthalmology, University of Arkansas for Medical Sciences
Hampton Roy Sr, MD is a member of the following medical societies: American Academy of Ophthalmology, American College of Surgeons, and Pan-American Association of Ophthalmology
Disclosure: Nothing to disclose.

 
 
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