Medication Summary
The goals of pharmacotherapy are to treat the infection, to reduce morbidity, and to prevent complications.
Antibiotics
Class Summary
A course of oral antibiotics is indicated if the hordeolum is complicated by preseptal cellulitis.
Cephalexin (Keflex, Biocef, Keftab)
First-generation cephalosporin often used in skin or skin structure infections (eg, acute hordeolum) caused by staphylococci or streptococci. Administered orally and has a half-life of 50-80 min. Only 10% is protein bound and greater than 90% recovered unchanged in urine.
Erythromycin base (E-Mycin)
Inhibits bacterial growth, possibly by blocking dissociation of peptidyl t-RNA from ribosomes, causing RNA-dependent protein synthesis to arrest.
Indicated for infections caused by susceptible strains of microorganisms and for prevention of corneal and conjunctival infections.
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