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Eyelid Myokymia Differential Diagnoses

  • Author: Byron L Lam, MD; Chief Editor: Edsel Ing, MD, FRCSC  more...
 
Updated: May 17, 2016
 
 

Diagnostic Considerations

Hemifacial spasm - Unilateral facial contraction due to seventh nerve dysfunction

Essential blepharospasm

Meige syndrome - Blepharospasm and oral facial dystonia

Spastic-paretic facial contracture - Unilateral tonic facial contracture due to pontine dysfunction, associated usually with multiple sclerosis, and brainstem tumors or vascular lesions

Differential Diagnoses

 
 
Contributor Information and Disclosures
Author

Byron L Lam, MD Professor, Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami School of Medicine

Byron L Lam, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Ophthalmology, American Medical Association, Phi Beta Kappa

Disclosure: Nothing to disclose.

Specialty Editor Board

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

Chief Editor

Edsel Ing, MD, FRCSC Associate Professor, Department of Ophthalmology and Vision Sciences, University of Toronto Faculty of Medicine; Consulting Staff, Hospital for Sick Children and Sunnybrook Hospital

Edsel Ing, MD, FRCSC is a member of the following medical societies: American Academy of Ophthalmology, American Association for Pediatric Ophthalmology and Strabismus, American Society of Ophthalmic Plastic and Reconstructive Surgery, Royal College of Physicians and Surgeons of Canada, Canadian Ophthalmological Society, North American Neuro-Ophthalmology Society, Canadian Society of Oculoplastic Surgery, European Society of Ophthalmic Plastic and Reconstructive Surgery, Canadian Medical Association, Ontario Medical Association, Statistical Society of Canada, Chinese Canadian Medical Society

Disclosure: Nothing to disclose.

Additional Contributors

Ron W Pelton, MD, PhD Private Practice, Colorado Springs, Colorado

Ron W Pelton, MD, PhD is a member of the following medical societies: American Academy of Ophthalmology, American College of Surgeons, AO Foundation, American Society of Ophthalmic Plastic and Reconstructive Surgery, Colorado Medical Society

Disclosure: Nothing to disclose.

References
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  2. Baldwin MR, Barbieri JT. Association of Botulinum neurotoxins with synaptic vesicle protein complexes. Toxicon. 2009 Apr 8. [Medline].

  3. Brin MF. Basic and clinical aspects of BOTOX((R)). Toxicon. 2009 Mar 31. [Medline].

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  5. Moe ST, Thompson AB, Smith GM, Fredenburg RA, Stein RL, Jacobson AR. Botulinum neurotoxin serotype A inhibitors: small-molecule mercaptoacetamide analogs. Bioorg Med Chem. 2009 Apr 15. 17(8):3072-9. [Medline].

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  7. Andermann F, et al. Facial myokymia in multiple sclerosis. Brain. 1961. 8:31-44.

  8. Banik R, Miller NR. Chronic myokymia limited to the eyelid is a benign condition. J Neuroophthalmol. 2004 Dec. 24(4):290-2. [Medline].

  9. Givner I, Jaffe NS. Myokymia of the eyelids; a suggestion as to therapy; preliminary report. Am J Ophthalmol. 1949 Jan. 32(1):51-5. [Medline].

  10. Krohel GB, Rosenberg PN. Oscillopsia associated with eyelid myokymia. Am J Ophthalmol. 1986 Nov 15. 102(5):662-3. [Medline].

  11. Lowe R. Facial Twitching. Trans Ophthalmol Soc Aust. 1951. 11:129-133.

  12. Reinecke RD. Translated myokymia of the lower eyelid causing uniocular vertical pseudonystagmus. Am J Ophthalmol. 1973 Jan. 75(1):150-1. [Medline].

  13. Rubin M, Root JD. Electrophysiologic investigation of benign eyelid twitching. Electromyogr Clin Neurophysiol. 1991 Sep. 31(6):377-81. [Medline].

  14. Scott AB. Botulinum toxin for blepharospasm. Spaeth G, Katz LJ, Parker KW, eds. Current Therapy in Ophthalmic Surgery. Toronto: Decker; 1989. 322-324.

  15. Sogg RL, Hoyt WF, Boldrey E. Spastic paretic facial contracture. A rare sign of brain stem tumor. Neurology. 1963 Jul. 13:607-12. [Medline].

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