eMedicine Specialties > Ophthalmology > Lid

Trichiasis: Treatment & Medication

Author: Robert H Graham, MD, Senior Associate Consultant, Department of Ophthalmology, Mayo Clinic, Scottsdale, Arizona
Contributor Information and Disclosures

Updated: Mar 24, 2009

Treatment

Medical Care

The primary treatment of trichiasis is surgical.

  • Lubricants, such as artificial tears and ointments, may decrease the irritant effect of lash rubbing.
  • If a more serious disease (eg, ocular cicatricial pemphigoid, Stevens-Johnson syndrome) is the cause of the lash misdirection, medical therapy should be geared toward that disease.
  • According to West and colleagues, azithromycin has been shown to reduce severe postsurgical trichiasis recurrence rates to 1 year.3

Surgical Care

Many procedures for the repair of trichiasis have been described. The technique used is dependent on the cause of the problem. These procedures can be categorized as lash/follicle destroying or lash/follicle repositioning.
  • Lash and follicle destruction surgery is preferred for segmental or focal trichiasis.
    • Simple epilation with forceps often leaves the lash follicle and usually is only a temporizing measure. When the lash grows back, it often will be short and stiff, and even more irritating.
    • Electrolysis of lashes can be effective, but it often is painful for the patient and tedious for the surgeon.
    • Cryosurgery of lashes and follicles can be very effective, but it has many potential complications.
    • Radiofrequency ablation of lashes and follicles is extremely effective and can be performed quickly and easily at the slit lamp or with surgical loupes and local anesthesia. The smallest gauge wire (eg, Ellman TA1, A8 bendable 1/16th vari tip) is introduced alongside the lash down to the follicle, with the lowest setting that gives an easy introduction of the wire. The machine should be set on cut/coag. A small "core sample" will be missing from the lid margin and will granulate in with minimal scarring.

      Lower lid trichiasis, Ellman radiofrequency folli...

      Lower lid trichiasis, Ellman radiofrequency follicle ablation.

      Lower lid trichiasis, Ellman radiofrequency folli...

      Lower lid trichiasis, Ellman radiofrequency follicle ablation.

    • Argon laser ablation can be effective, but it can be very tedious for both the patient and the surgeon, as well as expensive.
    • According to Moore and colleagues, ruby laser treatment can be a viable and well-tolerated option for the relief of the symptoms of trichiasis.4
    • Wedge resection of the lid segment requires a full-thickness resection of the lid margin; in many cases, it may be excessive.
  • Lash and follicle repositioning surgery should be directed toward the anatomical cause of the problem.
    • Entropion: Lower lid retractor reattachment and lateral tarsal strip can be used to repair most cases of horizontal lid laxity and entropion.
    • Posterior lamellar scarring
      • The posterior lamellae and fornix can be lengthened with grafts (eg, mucous membrane, hard palate, cadaveric dermis).
      • A tarsoconjunctival advancement may lengthen the posterior lamellae.
      • Tarsal fracture with full-thickness everting sutures repositions the lashes to point away from the globe.
      • Surgery of the conjunctiva may reactivate ocular cicatricial pemphigoid and should be avoided with this disease.
      • Repositioning of the anterior lamellae may be the method of choice when dealing with ocular cicatricial pemphigoid because it allows the conjunctiva to remain undisturbed. This technique positions the lashes away from the lid margin and further away from the globe.

Consultations

  • In cases of Stevens-Johnson syndrome or ocular cicatricial pemphigoid, a general medical consult may be necessary.
  • Cornea/external disease and/or oculoplastic services may be required in severe cases.

More on Trichiasis

Overview: Trichiasis
Differential Diagnoses & Workup: Trichiasis
Treatment & Medication: Trichiasis
Follow-up: Trichiasis
Multimedia: Trichiasis
References

References

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  2. Ngondi J, Gebre T, Shargie EB, et al. Risk factors for active trachoma in children and trichiasis in adults: a household survey in Amhara Regional State, Ethiopia. Trans R Soc Trop Med Hyg. May 2008;102(5):432-8. [Medline].

  3. West ES, Munoz B, Imeru A, Alemayehu W, Melese M, West SK. The association between epilation and corneal opacity among eyes with trachomatous trichiasis. Br J Ophthalmol. Feb 2006;90(2):171-4. [Medline].

  4. Moore J, De Silva SR, O'Hare K, Humphry RC. Ruby laser for the treatment of trichiasis. Lasers Med Sci. Mar 2009;24(2):137-9. [Medline].

  5. Bartley GB, Bullock JD, Olsen TG, Lutz PD. An experimental study to compare methods of eyelash ablation. Ophthalmology. Oct 1987;94(10):1286-9. [Medline].

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  7. Burton MJ, Bowman RJ, Faal H, et al. The long-term natural history of trachomatous trichiasis in the Gambia. Invest Ophthalmol Vis Sci. Mar 2006;47(3):847-52. [Medline].

  8. Burton MJ, Kinteh F, Jallow O, et al. A randomised controlled trial of azithromycin following surgery for trachomatous trichiasis in the Gambia. Br J Ophthalmol. Oct 2005;89(10):1282-8. [Medline].

  9. Chi MJ, Park MS, Nam DH, Moon HS, Baek SH. Eyelid splitting with follicular extirpation using a monopolar cautery for the treatment of trichiasis and distichiasis. Graefes Arch Clin Exp Ophthalmol. May 2007;245(5):637-40. [Medline].

  10. Collin RJO. Entropion and trichiasis. In: A Manual of Systemic Eyelid Surgery. New York: Churchill-Livingstone; 1989:7-26.

  11. Dhaliwal U, Nagpal G, Bhatia MS. Health-related quality of life in patients with trachomatous trichiasis or entropion. Ophthalmic Epidemiol. Feb 2006;13(1):59-66. [Medline].

  12. Durkin SR, Casson R, Newland HS, Selva D. Prevalence of trachoma and diabetes-related eye disease among a cohort of adult Aboriginal patients screened over the period 1999-2004 in remote South Australia. Clin Experiment Ophthalmol. May-Jun 2006;34(4):329-34. [Medline].

  13. Edwards T, Cumberland P, Hailu G, Todd J. Impact of health education on active trachoma in hyperendemic rural communities in Ethiopia. Ophthalmology. Apr 2006;113(4):548-55. [Medline].

  14. El Toukhy E, Lewallen S, Courtright P. Routine bilamellar tarsal rotation surgery for trachomatous trichiasis: short-term outcome and factors associated with surgical failure. Ophthal Plast Reconstr Surg. Mar-Apr 2006;22(2):109-12. [Medline].

  15. Elder MJ, Collin R. Anterior lamellar repositioning and grey line split for upper lid entropion in ocular cicatricial pemphigoid. Eye. 1996;10 (Pt 4):439-42. [Medline].

  16. Johnson RL, Collin JR. Treatment of trichiasis with a lid cryoprobe. Br J Ophthalmol. Apr 1985;69(4):267-70. [Medline].

  17. Jordan DR, Zafar A, Brownstein S, Faraji H. Cicatricial conjunctival inflammation with trichiasis as the presenting feature of Wegener granulomatosis. Ophthal Plast Reconstr Surg. Jan-Feb 2006;22(1):69-71. [Medline].

  18. Kersten RC, Kleiner FP, Kulwin DR. Tarsotomy for the treatment of cicatricial entropion with trichiasis. Arch Ophthalmol. May 1992;110(5):714-7. [Medline].

  19. Kuckelkorn R, Schrage N, Becker J, Reim M. Tarsoconjunctival advancement: a modified surgical technique to correct cicatricial entropion and metaplasia of the marginal tarsus. Ophthalmic Surg Lasers. Feb 1997;28(2):156-61. [Medline].

  20. Nagpal G, Dhaliwal U, Bhatia MS. Barriers to acceptance of intervention among patients with trachomatous trichiasis or entropion presenting to a teaching hospital. Ophthalmic Epidemiol. Feb 2006;13(1):53-8. [Medline].

  21. Polack S, Brooker S, Kuper H, Mariotti S, Mabey D, Foster A. Mapping the global distribution of trachoma. Bull World Health Organ. Dec 2005;83(12):913-9. [Medline].

  22. Rhatigan MC, Ashworth JL, Goodall K, Leatherbarrow B. Correction of blepharoconjunctivitis-related upper eyelid entropion using the anterior lamellar reposition technique. Eye. 1997;11 (Pt 1):118-20. [Medline].

  23. Shiu M, McNab AA. Cicatricial entropion and trichiasis in an urban Australian population. Clin Experiment Ophthalmol. Dec 2005;33(6):582-5. [Medline].

  24. Tirakunwichcha S, Tinnangwattana U, Hiranwiwatkul P, Rohitopakarn S. Folliculectomy: management in segmental trichiasis and distichiasis. J Med Assoc Thai. Jan 2006;89(1):90-3. [Medline].

  25. West ES, Alemayehu W, Munoz B, Melese M, Imeru A, West SK. Surgery for Trichiasis, Antibiotics to prevent Recurrence (STAR) Clinical Trial methodology. Ophthalmic Epidemiol. Aug 2005;12(4):279-86. [Medline].

  26. West S, Alemayehu W, Munoz B, Gower EW. Azithromycin prevents recurrence of severe trichiasis following trichiasis surgery: STAR trial. Ophthalmic Epidemiol. Sep-Oct 2007;14(5):273-7. [Medline].

  27. West SK, West ES, Alemayehu W, et al. Single-dose azithromycin prevents trichiasis recurrence following surgery: randomized trial in Ethiopia. Arch Ophthalmol. Mar 2006;124(3):309-14. [Medline].

  28. Wojono TH. Lid splitting with lash resection for cicatricial entropion. Ophthalmic Plast Reconst Surg. 1992;8:287-289.

  29. Wood JR, Anderson RL. Complications of cryosurgery. Arch Ophthalmol. Mar 1981;99(3):460-3. [Medline].

  30. Yeung YM, Hon CY, Ho CK. A simple surgical treatment for upper lid trichiasis. Ophthalmic Surg Lasers. Jan 1997;28(1):74-6. [Medline].

  31. Zhang H, Kandel RP, Atakari HK, Dean D. Impact of oral azithromycin on recurrence of trachomatous trichiasis in Nepal over 1 year. Br J Ophthalmol. Aug 2006;90(8):943-8. [Medline].

Further Reading

Keywords

trichiasis, ingrown eyelashes, lash inversion, lid abnormality, eyelid abnormality, eyelash misdirection, lash misdirection, misdirected lashes, misdirected eyelashes

Contributor Information and Disclosures

Author

Robert H Graham, MD, Senior Associate Consultant, Department of Ophthalmology, Mayo Clinic, Scottsdale, Arizona
Robert H Graham, MD is a member of the following medical societies: American Academy of Ophthalmology, American Medical Association, and Arizona Ophthalmological Society
Disclosure: WebMD/eMedicine Salary Employment

Medical Editor

Jorge G Camara, MD, Professor of Ophthalmology, Department of Surgery and Director of Fellowship Training Program in Ophthalmic Plastic and Reconstructive Surgery for Countries Served by the Aloha Medical Mission, University of Hawaii John A Burns School of Medicine
Jorge G Camara, MD is a member of the following medical societies: American Academy of Ophthalmology, American Medical Association, and American Society of Ophthalmic Plastic and Reconstructive Surgery
Disclosure: Nothing to disclose.

Pharmacy Editor

Simon K Law, MD, PharmD, Assistant Professor of Ophthalmology, Jules Stein Eye Institute; Chief of Section of Ophthalmology Surgical Services, Department of Veterans Affairs Healthcare Center, West Los Angeles
Simon K Law, MD, PharmD is a member of the following medical societies: American Academy of Ophthalmology, American Glaucoma Society, and Association for Research in Vision and Ophthalmology
Disclosure: Nothing to disclose.

Managing Editor

Mark T Duffy, MD, PhD, Consulting Staff, Division of Oculoplastic, Orbito-facial, Lacrimal and Reconstructive Surgery, Green Bay Eye Clinic, BayCare Clinic; Medical Director, Advanced Cosmetic Solutions, A BayCare Clinic
Mark T Duffy, MD, PhD is a member of the following medical societies: American Academy of Ophthalmology, American Medical Association, American Society of Ophthalmic Plastic and Reconstructive Surgery, Sigma Xi, and Society for Neuroscience
Disclosure: Allergan - Botox Cosmetic Consulting fee Consulting; Quest medical - lacrimal balloons Honoraria Speaking and teaching; Ortho-Neutrogenia Consulting fee Consulting

CME Editor

Lance L Brown, OD, MD, Ophthalmologist, Affiliated With Freeman Hospital and St John's Hospital, Regional Eye Center, Joplin, Missouri
Disclosure: Nothing to disclose.

Chief Editor

Hampton Roy Sr, MD, Associate Clinical Professor, Department of Ophthalmology, University of Arkansas for Medical Sciences
Hampton Roy Sr, MD is a member of the following medical societies: American Academy of Ophthalmology, American College of Surgeons, and Pan-American Association of Ophthalmology
Disclosure: Nothing to disclose.

 
 
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