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Astigmatic Keratotomy for the Correction of Astigmatism Treatment & Management

  • Author: James Hays, MD, MHA, MBA; Chief Editor: Hampton Roy, Sr, MD  more...
 
Updated: Dec 02, 2014
 

Surgical Therapy

While surgical techniques for astigmatic keratotomy (AK) vary based on surgeon preference (eg, blade type, cut depth, cut length, location and number of cuts), the basic principles remain the same. The following description of a standard astigmatic keratotomy procedure is provided for the less-experienced surgeon. Individual modifications certainly are expected as the surgeon's experience increases.[20, 21, 22, 23, 24, 25]

Developing the surgical plan

A surgical plan includes a combination of patient data (eg, refractive history, corneal topography/tomography findings, pachymetry findings, patient goals) with appropriate nomogram selection.

The following astigmatic keratotomy tenets help to explain how nomograms are adapted for each patient: the longer the incision, the greater the effect; the smaller the optical zone, the greater the effect; the less uncut tissue under the knife tip, the greater the effect.

The nomogram to follow is intended for limbal incisions (an approximate 11-mm optical zone) when the astigmatic target is 2.75 D or less. The addition of an 8-mm optical zone is reserved for attempted corrections of more than 3.0 D.

The depth of each incision should be calculated as 0.02 mm less than the thinnest depth measured by pachymetry in the area of the intended cut. Each incision requires the surgeon to perform pachymetry in the affected area and to reset the blade for each incision accordingly.

Incisions are generally paired and placed across the steep axis, but the surgeon may vary the relative length of each half of the pair based on topography. For example, if the nomogram calls for an arcuate incision that traverses 100°, one incision may traverse a 60° arc and one incision may traverse a 40° arc, each straddling the steep axis, if topography shows asymmetrical astigmatism.

While most RK nomograms assume a nominal patient age of 30 years, it is appropriate for astigmatic keratotomy nomograms to have an older nominal age set at 50 years. As many astigmatic keratotomy patients also have cataract, this nominal age works for almost everyone. Revise incision lengths based on this metric: Decrease the total length of the cut by 1° for each year after 50 years and increase the total length of the cut by 1° for each year before 50 years.

The following nomogram is applicable for patients who present with congenital astigmatism, with astigmatism at the time of cataract surgery, or revision of astigmatism following cataract surgery. Do not use this nomogram in patients who present with astigmatism following corneal transplant surgery because posttransplant astigmatism should not be treated with a standard nomogram. Instead, posttransplant astigmatism should be corrected based on individualized corneal healing patterns and topographical analysis.

Standard nomogram for astigmatic keratotomy

Based on the correction of corneal astigmatism at the limbus (an approximate 11-mm optical zone) in a 50 year-old patient:

  • 1 D - 80°
  • 1.5 D - 100°
  • 2 D - 120°
  • 2.5 D - 140°
  • 3 D - 160°

Standardastigmatic keratotomysurgical plan examples

Example 1. A 35-year-old patient presents with 2 D of congenital corneal astigmatism. Topography demonstrates an asymmetrical bow tie, with greater steepness in one hemi-meridian. The standard nomogram advises 120° of incision length, which is increased by 15° because of the patient’s age, totaling 135°. A 60° incision may be paired with a 75° incision, with the longer incision placed in the steeper hemi-meridian.

Example 2. A 50-year-old patient presents with 2 D of congenital corneal astigmatism. On topography, a symmetrical bow tie appearance is present. A pair of 60° incisions are placed, based on the nomogram presented. See the image below.

Example 2. Routine astigmatic keratotomy. In this Example 2. Routine astigmatic keratotomy. In this image, a nasal astigmatic keratotomy is shown. This image was taken minutes after performing the incision. Note that the area around the cut stains lightly with fluorescein.

Higher levels of astigmatism

To correct greater than 3 D of corneal astigmatism, an additional 1 D of astigmatic correction may be achieved in some cases by adding a pair of 40° incisions at the 8-mm optical zone. Because refractive variability increases as the optical zone is decreased, correction of higher astigmatic levels may be better approached in conjunction with LASIK.

Combining astigmatic keratotomy with cataract surgery

When treating against-the-rule astigmatism at the time of cataract surgery, it may be adequate to perform a standard cataract clear-corneal temporal incision and to place an extended astigmatic keratotomy incision nasally. If greater correction is required, make the cataract incision in the Langerman style using a 600-µm groove. At the end of the surgery, simply extend the groove to the appropriate length.

Astigmatic keratotomy after corneal transplantation

The architecture of astigmatism after corneal transplantation is quite different than with naturally occurring corneal astigmatism. The donor-recipient interface creates a new “artificial” limbus, which is typically 8 mm in diameter. Variable wound healing and scar contracture at the new limbal interface can induce high levels of cylinder. Mismatch of the donor and recipient tissues can also create high levels of permanent astigmatism. Moreover, the recipient bed of some transplanted eyes may be quite variable, as in the case of progressive keratoconus. Transplants performed because of herpes simplex infection and chemical burns may involve sewing normal elastic tissue into relatively scarred and inflexible beds, causing unpredictable amounts of postoperative astigmatism.

For these and other reasons, posttransplant cases do not conform to routine nomogram assessment. Astigmatism reduction in corneal transplant recipients should be based completely on physical inspection of the tissue and the topographical appearance of the ocular surface, since transplant recipients often present with asymmetrical astigmatism, irregular astigmatism, and/or high astigmatism.

To further confound results, refraction may be difficult or imprecise in these patients owing to high amounts of optical aberration and coexistent ocular morbidities. The most objective measurement is likely to be topographical astigmatism.

The first step when preparing a surgical plan for posttransplant astigmatism is to determine its cause. For instance, a patient with occult wound dehiscence might show excessive flattening in one hemi-meridian, producing severe astigmatism. In this case, a wedge resection would be a more appropriate procedure for excess flattening than astigmatic keratotomy surgery.

In areas of excessively dense wound contraction, be mindful that a small relaxing incision may go a long way, creating a large refractive effect. As a counterpoint to this, when recipient bed scarring exists, a relaxing incision may have relatively little effect. If there is no "give" in the cornea (eg, in a cornea scarred by herpes simplex), a relaxing incision may not budge the topographical shape or the patient’s refractive error.

Some form of intraoperative keratotomy or wavefront data capture is very helpful when correcting posttransplant astigmatism. A Morcher ring, an ocular response analyzer (ORA), or some similar intraoperative keratometric/wavefront device can provide the real-time effect of each incision as it is rendered.

Posttransplant astigmatic keratotomy surgical plan examples

Example 3. A 30-year-old patient presents with 3 D of refractive astigmatism following corneal graft surgery. Topography shows a somewhat symmetrical bowtie appearance, demonstrating even greater corneal astigmatism than the patient’s subjective response. The goal was to achieve a reduction of astigmatism using these values: A 100° incision was specified by the nomogram, which would then be increased by 20° owing to the patient's age. While a pair of 60° incisions was indicated on the standard nomogram, the surgeon’s prior experience led to a revision of the total arc to 90°.

Example 3. Preoperative topography in a patient ab Example 3. Preoperative topography in a patient about to undergo astigmatic keratotomy (AK) following corneal transplantation. This 30-year-old woman underwent corneal transplantation for keratoconus 6 years ago. She presented with a clear graft but with excessive astigmatism. Based on this pre-AK topography and prior surgical experience, an incision was placed just inside the donor-recipient interface from 250° to 300°. A second incision was placed between 30° and 70°. Incisions were not paired at 180° apart, but were localized based on topography. Refraction improved from +0.75 + 3.00 X 58° to +0.50 + 1.50 X 130°. Best-corrected vision remained 20/20.
Example 3. Postoperative topography following asti Example 3. Postoperative topography following astigmatic keratotomy for the 30-year-old woman with penetrating keratoplasty for keratoconus.

Example 4. A 75-year-old patient with prior history of penetrating keratoplasty presents with 2.5 D of refractive astigmatism. Topography shows a symmetrical bowtie appearance, yielding 6.5 D of corneal astigmatism. According to the nomogram, the 140° total arcuate incision indicated by the chart must be reduced by 25° based on the patient's age. A pair of 67.5° incisions is specified; however, this amount was titrated downward based on surgical experience.

Example 4. Topography shows preoperative and posto Example 4. Topography shows preoperative and postoperative readings with differential analysis in a corneal transplant recipient (performed for Fuchs dystrophy) who underwent astigmatic keratotomy (AK). After all sutures were removed, she had approximately 6.5 D of keratometric astigmatism. The previous sutures seemed to have been tighter temporally than nasally. She underwent AK with a 50° incision temporally and a 30° incision nasally. The alteration in arcuate size values was related to surgeon preference. Following AK, residual astigmatism was slightly less than 1 D. The 5.5 D of astigmatism alteration from an 80° relaxing incision in a normal cornea is not expected. Posttransplant corneas are variable, and individual results can vary widely. Monitor the results as best as possible intraoperatively and be willing to go back and suture an overcorrection if one should occur.
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Preoperative Details

The patient's record should reflect a fully documented surgical plan, accompanied by corneal topography of the operative eye for easy reference. Either affix these to the operating microscope or place them on a small cart or table next to the microscope. The surgeon must be able to reference the topography and plan at all times to avoid disorientation.

Administer 2 drops of topical anesthetic, such as proparacaine, into the operative eye 5 minutes apart followed by 1 drop of topical antibiotic. Skin should be prepared with betadine.

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Intraoperative Details

The patient enters the minor procedure room and sits upright in the chair. Instill a drop of topical anesthetic into the preoperative eye and, with the patient fixating at distance, mark the 6-o'clock and 12-o'clock locations at the limbus with a gentian violet skin scribe. The patient may then lie down under the microscope. Remember that, owing to cyclotorsion of the eye when the patient is reclined, the 6- and 12-o’clock marks may not appear in the same meridian as when sitting up and marked. All astigmatic keratotomy measurements should be based on the scribe marks.

The tip of the ultrasonic pachymeter should be cleaned with an alcohol pad. Wipe the tip dry with a sterile 4 x 4 pad or rinse with balanced salt solution (BSS), as any residual alcohol on the pachymeter tip can cause an abrasion when touched to the cornea. With manual opening of the lids (rather than with a lid speculum), measure and record the thickness of the cornea in the areas of incision placement.

To determine the diamond micrometer blade depth, take the thinnest pachymetry reading in the area where the first astigmatic keratotomy incision will be placed and subtract 0.02 mm from that measurement. Record this value on the surgical plan and set the depth of the knife blade under the operating microscope. Remember that each incision requires the surgeon to perform pachymetry in the affected area and to reset the blade for each incision accordingly.

Set the knife down on a protective block and insert the lid speculum.

An additional drop of anesthetic may be placed on the eye. Remove excess fluid from the cornea using a slightly moist Weck-Cel sponge. The 360° Thornton astigmatic ruler is used to mark the cornea.

Thornton astigmatic keratotomy ruler. Thornton astigmatic keratotomy ruler.

Line up the flanges with the previously placed 6-o'clock and 12-o'clock marks and lightly press the ruler onto the cornea.

The Thornton ring or Thornton-Fine ring may be used to fixate the globe. Identify the correct optical zone from the nomogram and locate the incision starting point using the 10° marks on the cornea. Firmly and perpendicularly enter the cornea with the diamond blade. Slowly cut along the desired arc and be vigilant for pooling, which may indicate inadvertent perforation. If a perforation occurs, remove the knife immediately and assess the incision. Microperforations require immediate pachymetry and blade depth check. When all is satisfactory, proceed. However, if a macro-perforation occurs, stop the procedure and consider suture of the incision if warranted. Perform no further incisions until the patient is fully healed and refractive stability is achieved.

Barring perforation (a rare phenomenon if careful pachymetry is used), when the desired arc is achieved, remove the knife and reset it for the appropriate depth of the next cut. Repeat this procedure until all cuts have been made. Then, remove the lid speculum.

Do not irrigate the cuts, especially if a small microperforation is present. Place a drop of topical antibiotic on the eye followed by 1-2 drops of a topical nonsteroid anti-inflammatory drug (NSAID). If a bilateral procedure is planned, move to the other eye.

Corneal transplant recipients

The technique differs somewhat in patients who have previously undergone corneal transplant surgery. Preoperatively, when marking the patient, use a skin scribe to precisely mark the limbal area that correlates to the steepest axis on topography. Again, this technique negates any possible cyclotorsion of the eye or misplacement of the 12-o'clock and 6-o'clock positions. It also negates any possible error in translation from topography to the eye.

In transplant recipients, astigmatic keratotomy incisions should be placed 0.5 mm within the transplanted tissue, rather than along the donor-recipient interface, because the interface may have variations in thickness, leading to inadvertent perforation. Measure the thickness of the cornea 0.5 mm central to the interface. Since the donor-recipient interface is the weakest spot in the cornea, do not plan to cut too deeply. Bias the knife at 85% of the measured pachymetry thickness for each area to be incised. It is better to use a slightly longer cut at slightly less depth, rather than a shorter and deeper cut, because the longer cut will provide smoother topography.

Moreover, use a triple-edged arcuate knife to create the arcuate incision parallel to the interface. After the initial incision, perform keratometry to determine its effect. When the cornea appears almost spherical, stop cutting, even if it means reducing the size of the arc compared with the presurgical plan. It is better to cut too little than too much. Remember, it is not necessary to completely neutralize astigmatism in the minor procedure room, as a continued flattening effect may be observed over the next week or so. If a significant overcorrection is noticed in the postoperative period, return to the operating room and suture the cut. The suture may be removed after 8 weeks.

Postoperatively, corneal transplant recipients are treated more frequently with topical antibiotics and steroids than used for routine astigmatic keratotomy. Remember that the eye is neurotrophic and epithelial healing may be problematic. Use adequate lubrication, especially if the patient has any tendency toward dry eye.

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Postoperative Details

Postoperative medications vary according to surgeon choice. Ofloxacin 0.3% used 4 times per day for 1 week provides adequate antibacterial coverage as the corneal re-epithelializes. A steroid drop, such as prednisolone acetate 1%, used 4 times per day for 1-2 weeks may help to stop or slow regression. A topical NSAID such as bromfenac 0.07% used 4 times per day for 4-7 days may reduce patient discomfort.

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Follow-up

Astigmatism is an ever-changing condition. Grene advises never trusting the results of a refractive surgical procedure until the 12-month postoperative gate is reached.[3] Be conservative when it comes to enhancement; patients may present years later for repeat or enhancement surgery, and surgery performed at the limbus may be repeated as necessary.

For excellent patient education resources, visit eMedicineHealth's Eye and Vision Center. Also, see eMedicineHealth's patient education article Vision Correction Surgery.

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Complications

A well-performed astigmatic keratotomy has relatively few complications, as it is one of the safest procedures in ophthalmology.

If overcorrection is noted on topography and/or refraction within a month of astigmatic keratotomy surgery, close the incision by placing one or two 10-0 Vicryl sutures in the excessively flattened hemi-meridian. The sutures do not require removal, as they will dissolve in time after their function is complete.

Undercorrection can be addressed easily with one of two methods. First, retake ultrasonic pachymetry measurements in the area of the incisions. If pachymetry values measure significantly thicker after astigmatic keratotomy surgery, recut the original incisions at 90% of the greater depth. If, however, the depth seems to be adequate based on similar pre– and post–astigmatic keratotomy pachymetry measurements, recut the incisions and extend the length of each incision by increments of 10° to enhance the effect.

Occasionally, late regression of the astigmatic result can be observed. Astigmatic keratotomy incisions placed at the limbus are closer to the blood supply than incisions at a smaller optical zone and thus may have a greater tendency to regress. If late regression occurs, recut the same incision. Treat the patient with topical steroids 4 times per day for 4-6 weeks after the procedure to inhibit the tendency to heal too aggressively.

One of the most serious and avoidable complications of astigmatic keratotomy surgery is using a small optical zone for arcuate incision placement. In the early days of astigmatic keratotomy, some surgeons advocated using optical zones as small as 4 mm in diameter, which frequently caused a decrease in best-corrected vision and created disabling optical aberrations. These complications have essentially been rendered obsolete with the move of the incision to the limbus.

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Contributor Information and Disclosures
Author

James Hays, MD, MHA, MBA Consulting Staff, Department of Corneal Transplantation and Refractive Surgery, Atlanta Eye Surgery Center

Disclosure: Received salary from Alimera Sciences for consulting.

Coauthor(s)

Debra M Stone, OD, MS Consultative Optometrist and Outcomes Analyst, Woolfson Eye Institute

Debra M Stone, OD, MS is a member of the following medical societies: American Academy of Optometry, Georgia Optometric Association

Disclosure: Nothing to disclose.

Specialty Editor Board

Simon K Law, MD, PharmD Clinical Professor of Health Sciences, Department of Ophthalmology, Jules Stein Eye Institute, University of California, Los Angeles, David Geffen School of Medicine

Simon K Law, MD, PharmD is a member of the following medical societies: American Academy of Ophthalmology, Association for Research in Vision and Ophthalmology, American Glaucoma Society

Disclosure: Nothing to disclose.

Louis E Probst, MD, MD Medical Director, TLC Laser Eye Centers

Louis E Probst, MD, MD is a member of the following medical societies: American Academy of Ophthalmology, American Society of Cataract and Refractive Surgery, International Society of Refractive Surgery

Disclosure: Nothing to disclose.

Chief Editor

Hampton Roy, Sr, MD Associate Clinical Professor, Department of Ophthalmology, University of Arkansas for Medical Sciences

Hampton Roy, Sr, MD is a member of the following medical societies: American Academy of Ophthalmology, American College of Surgeons, Pan-American Association of Ophthalmology

Disclosure: Nothing to disclose.

Additional Contributors

Daniel S Durrie, MD Director, Department of Ophthalmology, Division of Refractive Surgery, University of Kansas Medical Center

Daniel S Durrie, MD is a member of the following medical societies: American Academy of Ophthalmology, Association for Research in Vision and Ophthalmology

Disclosure: Received grant/research funds from Alcon Labs for independent contractor; Received grant/research funds from Abbott Medical Optics for independent contractor; Received ownership interest from Acufocus for consulting; Received ownership interest from WaveTec for consulting; Received grant/research funds from Topcon for independent contractor; Received grant/research funds from Avedro for independent contractor; Received grant/research funds from ReVitalVision for independent contractor.

Acknowledgements

Mauro Fioretto, MD Professor of Ophthalmology, University Eye Clinic of Genova; Head of Ophthalmology Department, Hospital of Casale Monferrato, Italy

Disclosure: Nothing to disclose.

Vincenzo Orfeo, MD Head, Operating Unit, Clinica Mediterranea, Naples, Italy

Vincenzo Orfeo, MD is a member of the following medical societies: American Academy of Ophthalmology

Disclosure: Nothing to disclose.

Antonio Pascotto, MD Consulting Ophthalmologist, Pascotto, Istituto per la Salute degli Occhi, Clinica Mediterranea, Italy

Disclosure: Nothing to disclose.

Sergio Claudio Saccà, PhD Professor of Ophthalmology, Department of Neurological and Visual Sciences, Ospedale San Martino, Italy

Disclosure: Nothing to disclose.

Spencer Thornton, MD Medical Director, Thornton Eye Center

Spencer Thornton, MD is a member of the following medical societies: American Academy of Ophthalmology and American College of Surgeons

Disclosure: Nothing to disclose.

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Thornton astigmatic keratotomy ruler.
Close-up view of Thornton astigmatic keratotomy ruler.
Example 2. Routine astigmatic keratotomy. In this image, a nasal astigmatic keratotomy is shown. This image was taken minutes after performing the incision. Note that the area around the cut stains lightly with fluorescein.
Example 3. Preoperative topography in a patient about to undergo astigmatic keratotomy (AK) following corneal transplantation. This 30-year-old woman underwent corneal transplantation for keratoconus 6 years ago. She presented with a clear graft but with excessive astigmatism. Based on this pre-AK topography and prior surgical experience, an incision was placed just inside the donor-recipient interface from 250° to 300°. A second incision was placed between 30° and 70°. Incisions were not paired at 180° apart, but were localized based on topography. Refraction improved from +0.75 + 3.00 X 58° to +0.50 + 1.50 X 130°. Best-corrected vision remained 20/20.
Example 3. Postoperative topography following astigmatic keratotomy for the 30-year-old woman with penetrating keratoplasty for keratoconus.
Example 4. Topography shows preoperative and postoperative readings with differential analysis in a corneal transplant recipient (performed for Fuchs dystrophy) who underwent astigmatic keratotomy (AK). After all sutures were removed, she had approximately 6.5 D of keratometric astigmatism. The previous sutures seemed to have been tighter temporally than nasally. She underwent AK with a 50° incision temporally and a 30° incision nasally. The alteration in arcuate size values was related to surgeon preference. Following AK, residual astigmatism was slightly less than 1 D. The 5.5 D of astigmatism alteration from an 80° relaxing incision in a normal cornea is not expected. Posttransplant corneas are variable, and individual results can vary widely. Monitor the results as best as possible intraoperatively and be willing to go back and suture an overcorrection if one should occur.
 
 
 
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