eMedicine Specialties > Ophthalmology > Refractive Disorders

Astigmatism, LASIK: Follow-up

Author: David R Hardten, MD, Phillips Eye Institute; Adjunct Clinical Associate Professor, Director of Refractive Surgery at Minnesota Eye Consultants, Pennsylvania College of Optometry; Clinical Associate Professor, Department of Ophthalmology, University of Minnesota, Minnesota VAMC
Coauthor(s): Ahmad M Fahmy, OD, Fellow, Department of Ophthalmology, Minnesota Eye Consultants; Scott G Hauswirth, OD, Consulting Staff, Department of Optometry, Minnesota Eye Consultants
Contributor Information and Disclosures

Updated: Jan 2, 2007

Outcome and Prognosis

Astigmatic correction results using the excimer laser steadily have improved as surgical techniques have improved. Several years ago, Nordan et al reported a series of 5 eyes with postkeratoplasty anisometropia treated with the excimer laser. The mean preoperative myopia was -7.40±4.37 D with a mean of +3.05±1.47 D of astigmatism. Postoperatively, the myopia was reduced to a mean of -3.35±3.04 D, and the astigmatism was reduced to +1.30±0.60 D. The improvement in refractive error also was associated with an improvement in uncorrected visual acuities. Thirteen eyes with high astigmatism were treated with a rotating mask system using the Aesculap Meditec MEL 193-nm excimer laser. In this study, the astigmatism was reduced an average of 2.80 D. Inadequate correction was seen in some patients due to decentration of the ablation. Haze was seen in most patients but was graded as severe in only 2 patients and eventually cleared with topical steroids.

The ability of the excimer laser to treat high levels of astigmatism in all degrees of myopia also was examined by Lee et al. One hundred ten eyes were included in the study with myopic spherical component ranging from -3.00 D to -13.00 D, and astigmatic component ranging from -2.00 D to -5.50 D. All ablations were completed with an elliptical and multizone treatment pattern. Results were examined using vector analysis and showed that the low-to-moderate levels of myopia had a high level of predictability. However, high levels of myopia, greater than -10.25 D, showed little improvement in astigmatic correction in this study.

The authors' group reported a series of 19 eyes undergoing LASIK for hyperopic astigmatism. Preoperative average hyperopia was +2.20 D±0.99, and cylinder corrections ranged from 0 D to 4.50 D. Postoperatively, no eyes lost more than 2 lines of best-corrected visual acuity, and 63% of eyes were within +1.00 D of emmetropia. In the eyes with the longest follow-up care (6 mo), refractive stability was good, although it was still unclear if the slight tendency for the primary hyperopes to regress would continue over the long term. In both groups, however, predictability was good, and patients gained excellent uncorrected visual acuity quickly after surgery. This suggests that LASIK may help hyperopic astigmatic patients resume a normal, active lifestyle after only a brief recovery period.

Another study by this group looked at the results of LASIK for myopic astigmatism and compared unilateral and bilateral treatments. The procedure rapidly reduced spherical equivalent and astigmatism in both groups. No statistical difference in spherical equivalent or astigmatism was noted postoperatively between groups. The effect of LASIK on the astigmatism was rapid and remained stable without regression between the visits at 1 day and 1 month and between visits at 1 month and 1 year in both the unilateral (p=1, p=0.94) and bilateral groups (p=0.14, p=0.45). The difference in cylinder between the unilateral and bilateral groups was not statistically significant at any of the postoperative visits.

Another study by Febbraro et al examined the efficacy of excimer laser photoastigmatic refractive keratectomy in patients treated with a Nidek EC 5000 excimer laser. Preoperative myopia averaged -4.50 D, and average astigmatism preoperatively was -1.64 D. Results at 1 year showed residual subjective astigmatism to be -0.40 D. Uncorrected visual acuity of 20/40 or better occurred in 22 out of 27 eyes and 21 of the eyes were within ± -1.00 D of emmetropia.

In a study by Vinciguerra et al, 25 eyes underwent correction for hyperopic astigmatism using the excimer laser with an algorithm designed to remove as little tissue as possible. Mean preoperative hyperopia was +3.76±1.70 D, and mean preoperative cylinder was 2.20±0.80 D. Six month follow-up results showed that mean sphere was corrected by 3.08 D and mean cylinder by 1.60 D, while best-corrected visual acuity actually improved.

As is clearly demonstrated, PRK and LASIK are predictable and effective means of correcting various types and degrees of ametropia, including astigmatism.

Future and Controversies

The excimer laser is now frequently used to correct astigmatism. Although early results appear promising, whether the excimer laser procedure will completely replace incisional astigmatic keratotomy awaits to be seen. Complications are unusual and if managed appropriately, a minimal incidence of losing best-corrected visual acuity exists. Thorough understanding of the corneal response to both incisional astigmatic surgery as well as excimer laser correction of astigmatism is essential to refractive surgeons. As these responses are better understood and as software packages are refined, more success using excimer laser techniques is expected.

Continued advancements in many areas of refractive surgery are improving results obtained in correction of astigmatism. The excimer laser used to resculpt the cornea under a corneal flap in the LASIK procedure is currently the most reliable method of correcting astigmatism. Proper attention to surgical details as well as preoperative and postoperative management will continue to provide safe and reliable astigmatic corrections.

 


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References

References

  1. Abad JC, An B, Power WJ, et al. A prospective evaluation of alcohol-assisted versus mechanical epithelial removal before photorefractive keratectomy. Ophthalmology. Oct 1997;104(10):1566-74; discussion 1574-5. [Medline].

  2. Agrawal VB, Hanuch OE, Bassage S, Aquavella JV. Alcohol versus mechanical epithelial debridement: effect on underlying cornea before excimer laser surgery. J Cataract Refract Surg. Oct 1997;23(8):1153-9. [Medline].

  3. Aizawa D, Shimizu K, Komatsu M, et al. Clinical outcomes of wavefront-guided laser in situ keratomileusis: 6-month follow-up. J Cataract Refract Surg. Aug 2003;29(8):1507-13. [Medline].

  4. Akura J, Matsuura K, Hatta S, et al. Clinical application of full-arc, depth-dependent, astigmatic keratotomy. Cornea. Nov 2001;20(8):839-43. [Medline].

  5. Amano S, Tanaka S, Shimizu K. Topographical evaluation of centration of excimer laser myopic photorefractive keratectomy. J Cataract Refract Surg. Nov 1994;20(6):616-9. [Medline].

  6. Amm M, Duncker GI, Schroder E. Excimer laser correction of high astigmatism after keratoplasty. J Cataract Refract Surg. Apr 1996;22(3):313-7. [Medline].

  7. Argento CJ, Cosentino MJ. Laser in situ keratomileusis for hyperopia. J Cataract Refract Surg. Aug 1998;24(8):1050-8. [Medline].

  8. Argento CJ, Cosentino MJ, Biondini A. Treatment of hyperopic astigmatism. J Cataract Refract Surg. Dec 1997;23(10):1480-90. [Medline].

  9. Arrowsmith PN, Marks RG. Visual, refractive, and keratometric results of radial keratotomy. Five- year follow-up. Arch Ophthalmol. Apr 1989;107(4):506-11. [Medline].

  10. Arrowsmith PN, Marks RG. Visual, refractive, and keratometric results of radial keratotomy. A two-year follow-up. Arch Ophthalmol. Jan 1987;105(1):76-80. [Medline].

  11. Bates WH. A suggestion of an operation to correct astigmatism. 1894. Refract Corneal Surg. Jan-Feb 1989;5(1):58-9. [Medline].

  12. Belmont SC, Lazzaro DR, Muller JW, Troutman RC. Combined wedge resection and relaxing incisions for astigmatism after penetrating keratoplasty. J Refract Surg. Nov-Dec 1995;11(6):472-6. [Medline].

  13. Campos M, Wang XW, Hertzog L, et al. Ablation rates and surface ultrastructure of 193 nm excimer laser keratectomies. Invest Ophthalmol Vis Sci. Jul 1993;34(8):2493-500. [Medline].

  14. Chayet AS, Magallanes R, Montes M, et al. Laser in situ keratomileusis for simple myopic, mixed, and simple hyperopic astigmatism. J Refract Surg. Apr 1998;14(2 Suppl):S175-6. [Medline].

  15. Dausch D, Klein R, Landesz M, Schroder E. Photorefractive keratectomy to correct astigmatism with myopia or hyperopia. J Cataract Refract Surg. Mar 1994;20 Suppl:252-7. [Medline].

  16. Davidorf JM, Zaldivar R, Oscherow S. Results and complications of laser in situ keratomileusis by experienced surgeons. J Refract Surg. Mar-Apr 1998;14(2):114-22. [Medline].

  17. Deitz MR, Sanders DR, Marks RG. Radial keratotomy: an overview of the Kansas City study. Ophthalmology. May 1984;91(5):467-78. [Medline].

  18. Ditzen K, Huschka H, Pieger S. Laser in situ keratomileusis for hyperopia. J Cataract Refract Surg. Jan 1998;24(1):42-7. [Medline].

  19. Duffey RJ, Tchah H, Lindstrom RL. Spoke keratotomy in the human cadaver eye. J Refract Surg. 1988;4:9.

  20. Faber E. Operative Behandeling van Astigmatisme. Ned Tijdschr Geneeskd. 1895;2:495.

  21. Faktorovich EG, Maloney RK, Price FW. Effect of astigmatic keratotomy on spherical equivalent: results of the Astigmatism Reduction Clinical Trial. Am J Ophthalmol. Mar 1999;127(3):260-9. [Medline].

  22. Febbraro JL, Aron-Rosa D, Gross M, et al. One year clinical results of photoastigmatic refractive keratectomy for compound myopic astigmatism. J Cataract Refract Surg. Jul 1999;25(7):911-20. [Medline].

  23. Franks JB, Binder PS. Keratotomy procedures for the correction of astigmatism. J Refract Surg. 1985;1:11.

  24. Fyodorov SN, Durnev VV. Surgical correction of complicated myopic astigmatism by means of dissection of circular ligament of cornea. Ann Ophthalmol. Jan 1981;13(1):115-8. [Medline].

  25. Gartry DS, Kerr Muir MG, Marshall J. Excimer laser photorefractive keratectomy. 18-month follow-up. Ophthalmology. Aug 1992;99(8):1209-19. [Medline].

  26. Hardten DR, Lindstrom RL. Surgical correction of refractive errors after penetrating keratoplasty. Int Ophthalmol Clin. Winter 1997;37(1):1-35. [Medline].

  27. Hardten DR, Lindstrom RL. Management of lasik complications. Operatives Techniques in Cataract Surgery. 1998;1:32-9.

  28. Hennekes R. Holmium:YAG laser thermokeratoplasty for correction of astigmatism. J Refract Surg. May-Jun 1995;11(3 Suppl):S358-60. [Medline].

  29. Ibrahim O. Laser in situ keratomileusis for hyperopia and hyperopic astigmatism. J Refract Surg. Apr 1998;14(2 Suppl):S179-82. [Medline].

  30. Jabbur NS, Kraff C. Wavefront-guided laser in situ keratomileusis using the WaveScan system for correction of low to moderate myopia with astigmatism: 6-month results in 277 eyes. J Cataract Refract Surg. Aug 2005;31(8):1493-501. [Medline].

  31. Jaffe NS, Clayman HM. The pathophysiology of corneal astigmatism after cataract extraction. Ophthalmology. 1975;79:615-30.

  32. Jain S, Khoury JM, Chamon W, Azar DT. Corneal light scattering after laser in situ keratomileusis and photorefractive keratectomy. Am J Ophthalmol. Oct 1995;120(4):532-4. [Medline].

  33. Jankov MR, Panagopoulou SI, Tsiklis NS. Topography-guided treatment of irregular astigmatism with the wavelight excimer laser. J Refract Surg. Apr 2006;22(4):335-44. [Medline].

  34. Knorz MC, Liermann A, Jendritza B, Hugger P. LASIK for hyperopia and hyperopic astigmatism--results of a pilot study. Semin Ophthalmol. Jun 1998;13(2):83-7. [Medline].

  35. Koffler BH, Smith VM. Corneal topography, arcuate keratotomy, and compression sutures for astigmatism after penetrating keratoplasty. J Refract Surg. Feb 1996;12(2):S306-9. [Medline].

  36. Krachmer JH, Fenzl RE. Surgical correction of high postkeratoplasty astigmatism. Relaxing incisions vs wedge resection. Arch Ophthalmol. Aug 1980;98(8):1400-2. [Medline].

  37. Lans LJ. Experimentelle Untersuchungen über Entstehung von Astigmatismus durch nich-perforirende Corneawunden. Graefes Arch Ophthalmol. 1898;45:117.

  38. Lavery GW, Lindstrom RL, Hofer LA, Doughman DJ. The surgical management of corneal astigmatism after penetrating keratoplasty. Ophthalmic Surg. Mar 1985;16(3):165-9. [Medline].

  39. Lee JS, Oum BS, Lee BJ, Lee SH. Photorefractive keratectomy for astigmatism greater than -2.00 diopters in eyes with low, high, or extreme myopia. J Cataract Refract Surg. Nov 1998;24(11):1456-63. [Medline].

  40. Lindstrom RL. The surgical correction of astigmatism: a clinician''s perspective. Refract Corneal Surg. Nov-Dec 1990;6(6):441-54. [Medline].

  41. Linebarger EJ, Hardten DR, Lindstrom RL. Sands of the sahara. In: Curatto, Brint, eds. LASIK: Surgical Techniques and Complications. Thorofa;. 1999:591-6.

  42. MacDonald IM, Zabel RW, Chen V. Corneal astigmatism generation and correction using a fiberoptic-delivered holmium laser. Invest Ophthalmol. 1990;31:S476.

  43. Mandel MR, Shapiro MB, Krachmer JH. Relaxing incisions with augmentation sutures for the correction of postkeratoplasty astigmatism. Am J Ophthalmol. Mar 15 1987;103(3 Pt 2):441-7. [Medline].

  44. Mrochen M, Kaemmerer M, Seiler T. Clinical results of wavefront-guided laser in situ keratomileusis 3 months after surgery. J Cataract Refract Surg. Feb 2001;27(2):201-7. [Medline].

  45. Munnerlyn CR, Koons SJ, Marshall J. Photorefractive keratectomy: a technique for laser refractive surgery. J Cataract Refract Surg. Jan 1988;14(1):46-52. [Medline].

  46. Niesen UM, Businger U, Schipper I. Disability glare after excimer laser photorefractive keratectomy for myopia. J Refract Surg. Feb 1996;12(2):S267-8. [Medline].

  47. Nordan LT, Binder PS, Kassar BS, Heitzmann J. Photorefractive keratectomy to treat myopia and astigmatism after radial keratotomy and penetrating keratoplasty. J Cataract Refract Surg. May 1995;21(3):268-73. [Medline].

  48. Pallikaris IG, Siganos DS. Excimer laser in situ keratomileusis and photorefractive keratectomy for correction of high myopia. J Refract Corneal Surg. Sep-Oct 1994;10(5):498-510. [Medline].

  49. Parker PJ, Klyce SD, Ryan BL. Central topographical islands following photorefractive keratectomy. Invest Ophthalmol Vis Sci. 1993;34:803.

  50. Partal AE, Manche EE. CustomVue laser in situ keratomileusis for myopia and myopic astigmatism using the Visx S4 excimer laser: Efficacy, predictability, and safety. J Cataract Refract Surg. Mar 2006;32(3):475-9. [Medline].

  51. Price FW, Grene RB, Marks RG, Gonzales JS. Astigmatism reduction clinical trial: a multicenter prospective evaluation of the predictability of arcuate keratotomy. Evaluation of surgical nomogram predictability. ARC-T Study Group. Arch Ophthalmol. Mar 1995;113(3):277-82. [Medline].

  52. Sato T. Treatment of conical cornea by incision of Descemet's membrane. Acta Soc Ophthalmol Jrn. 1939;43:541.

  53. Sato T. Experimental study on surgical correction of astigmatism. Juntendo Kenkyukaizasshi. 1943;589:37.

  54. Sato T. Posterior incision of the cornea: Surgical treatment for conical cornea and astigmatism. Am J Ophthalmol. 1950;33:943.

  55. Sato T. Die operative Behandlung des Astigmatismus. Klin Monatsbl Augenheilkd. 1955;126:16.

  56. Schallhorn SC, Blanton CL, Kaupp SE, et al. Preliminary results of photorefractive keratectomy in active-duty United States Navy personnel. Ophthalmology. Jan 1996;103(1):5-22. [Medline].

  57. Schiotz LJ. Hin Fall von hochgradigem Hornhautstastigmatismus nach Staarextraction: Bessergung auf operativem Wege. Arch Augenheilkd. 1885;15:178.

  58. Seiler T, Kaemmerer M, Mierdel P, Krinke HE. Ocular optical aberrations after photorefractive keratectomy for myopia and myopic astigmatism. Arch Ophthalmol. Jan 2000;118(1):17-21. [Medline].

  59. Seiler T, Matallana M, Bende T. Laser thermokeratoplasty by means of a pulsed holmium:YAG laser for hyperopic correction. Refract Corneal Surg. Sep-Oct 1990;6(5):335-9. [Medline].

  60. Shah S, Smith RJ, Pieger S, Chatterjee A. Effect of an elliptical optical zone on outcome of photoastigmatic refractive keratectomy. J Refract Surg. Mar-Apr 1999;15(2 Suppl):S188-91. [Medline].

  61. Shen EP, Yang CN, Hu FR. Corneal astigmatic change after photorefractive keratectomy and photoastigmatic refractive keratectomy. J Cataract Refract Surg. Mar 2002;28(3):491-8. [Medline].

  62. Sher NA, Chen V, Bowers RA, et al. The use of the 193-nm excimer laser for myopic photorefractive keratectomy in sighted eyes. A multicenter study. Arch Ophthalmol. Nov 1991;109(11):1525-30. [Medline].

  63. Sher NA, Bowers RA, Zabel RW, et al. Clinical use of the 193-nm excimer laser in the treatment of corneal scars. Arch Ophthalmol. Apr 1991;109(4):491-8. [Medline].

  64. Stein HA, Stein RM, Price C, Salim GA. Alcohol removal of the epithelium for excimer laser ablation: outcomes analysis. J Cataract Refract Surg. Oct 1997;23(8):1160-3. [Medline].

  65. Sugar J, Kirk AK. Relaxing keratotomy for post-keratoplasty high astigmatism. Ophthalmic Surg. Feb 1983;14(2):156-8. [Medline].

  66. Suzuki A, Maeda N, Watanabe H, et al. Using a reference point and videokeratography for intraoperative identification of astigmatism axis. J Cataract Refract Surg. Dec 1997;23(10):1491-5. [Medline].

  67. Talley AR, Hardten DR, Sher NA, et al. Results one year after using the 193-nm excimer laser for photorefractive keratectomy in mild to moderate myopia. Am J Ophthalmol. Sep 15 1994;118(3):304-11. [Medline].

  68. Thompson V. Holmium:YAG laser thermokeratoplasty for correction of astigmatism. J Refract Corneal Surg. 1994;10:S293.

  69. Trokel SL, Srinivasan R, Braren B. Excimer laser surgery of the cornea. Am J Ophthalmol. Dec 1983;96(6):710-5. [Medline].

  70. Troutman RC, Swinger C. Relaxing incision for control of postoperative astigmatism following keratoplasty. Ophthalmic Surg. Feb 1980;11(2):117-20. [Medline].

  71. Uozato H, Guyton DL. Centering corneal surgical procedures. Am J Ophthalmol. Mar 15 1987;103(3 Pt 1):264-75. [Medline].

  72. Verdon W, Bullimore M, Maloney RK. Visual performance after photorefractive keratectomy. A prospective study. Arch Ophthalmol. Dec 1996;114(12):1465-72. [Medline].

  73. Vinciguerra P, Epstein D, Azzolini M, et al. Algorithm to correct hyperopic astigmatism with the Nidek EC-5000 excimer laser. J Refract Surg. Mar-Apr 1999;15(2 Suppl):S186-7. [Medline].

  74. Waring GO. History of radial keratotomy. In: Sanders DR, Hofmann RF, Salz JJ, eds. Refractive Corneal Surgery. Thorofare, NJ;. 1985:3-14.

  75. Webber SK, McGhee CN, Bryce IG. Decentration of photorefractive keratectomy ablation zones after excimer laser surgery for myopia. J Cataract Refract Surg. Apr 1996;22(3):299-303. [Medline].

  76. Werblin TP. Lans lecture. Lamellar refractive surgery: where have we been and where are we going?. Refract Corneal Surg. May-Jun 1989;5(3):167-76. [Medline].

Further Reading

Keywords

LASIK, astigmatism, PRK, PARK, refractive error, refraction, photoastigmatic refractive keratectomy, conventional laser in-situ keratomileusis, wavefront-guided laser in-situ keratomileusis, wavefront-guided LASIK, photorefractive keratoplasty, laser epithelial keratomileusis, LASEK, astigmatic keratotomy

Contributor Information and Disclosures

Author

David R Hardten, MD, Phillips Eye Institute; Adjunct Clinical Associate Professor, Director of Refractive Surgery at Minnesota Eye Consultants, Pennsylvania College of Optometry; Clinical Associate Professor, Department of Ophthalmology, University of Minnesota, Minnesota VAMC
David R Hardten, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Ophthalmology, American College of Surgeons, American Medical Association, American Society of Cataract and Refractive Surgery, and International Society of Refractive Surgery
Disclosure: Alcon, Allergan, AMO, TLCVision, STAAR, Kolis, Ophtec Grant/research funds Other

Coauthor(s)

Ahmad M Fahmy, OD, Fellow, Department of Ophthalmology, Minnesota Eye Consultants
Ahmad M Fahmy, OD is a member of the following medical societies: American Academy of Optometry and American Optometric Association
Disclosure: Nothing to disclose.

Scott G Hauswirth, OD, Consulting Staff, Department of Optometry, Minnesota Eye Consultants
Scott G Hauswirth, OD is a member of the following medical societies: International Society of Refractive Surgery
Disclosure: Nothing to disclose.

Medical Editor

Daniel S Durrie, MD, Director, Department of Ophthalmology, Division of Refractive Surgery, University of Kansas Medical Center
Daniel S Durrie, MD is a member of the following medical societies: American Academy of Ophthalmology and Association for Research in Vision and Ophthalmology
Disclosure: Nothing to disclose.

Pharmacy Editor

Simon K Law, MD, PharmD, Assistant Professor of Ophthalmology, Jules Stein Eye Institute; Chief of Section of Ophthalmology Surgical Services, Department of Veterans Affairs Healthcare Center, West Los Angeles
Simon K Law, MD, PharmD is a member of the following medical societies: American Academy of Ophthalmology, American Glaucoma Society, and Association for Research in Vision and Ophthalmology
Disclosure: Nothing to disclose.

Managing Editor

Louis E Probst, MD, Medical Director of Refractive Surgery, Chicago, Madison, Milwaukee, and Windsor Centers, TLC the Laser Eye Centers
Louis E Probst, MD is a member of the following medical societies: American Academy of Ophthalmology, American Society of Cataract and Refractive Surgery, and International Society of Refractive Surgery
Disclosure: Nothing to disclose.

CME Editor

Lance L Brown, OD, MD, Ophthalmologist, Affiliated With Freeman Hospital and St John's Hospital, Regional Eye Center, Joplin, Missouri
Disclosure: Nothing to disclose.

Chief Editor

Hampton Roy Sr, MD, Associate Clinical Professor, Department of Ophthalmology, University of Arkansas for Medical Sciences
Hampton Roy Sr, MD is a member of the following medical societies: American Academy of Ophthalmology, American College of Surgeons, and Pan-American Association of Ophthalmology
Disclosure: Nothing to disclose.

 
 
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