LASEK Workup

  • Author: Sanjeev Grewal, MD, FRCSC; Chief Editor: Hampton Roy Sr, MD   more...
 
Updated: Oct 26, 2010
 

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Contributor Information and Disclosures
Author

Sanjeev Grewal, MD, FRCSC  Associate Professor of Ophthalmology, Chief, Cornea and Refractive Surgery, Residency Program Director, Department of Ophthalmology, Medical Faculty Associates, George Washington University

Sanjeev Grewal, MD, FRCSC is a member of the following medical societies: American Academy of Ophthalmology, Association for Research in Vision and Ophthalmology, College of Physicians and Surgeons of Ontario, and Royal College of Physicians and Surgeons of Canada

Disclosure: Nothing to disclose.

Coauthor(s)

Reecha Sachdeva, MD  Resident Physician, Cole Eye Institute, Cleveland Clinic

Reecha Sachdeva, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Ophthalmology, and American Medical Student Association/Foundation

Disclosure: Nothing to disclose.

Brad Feldman, MD  Cornea, Cataract, and Refractive Surgeon, Philadelphia Eye Associates

Brad Feldman, MD is a member of the following medical societies: American Academy of Ophthalmology, American Society of Cataract and Refractive Surgery, and Association for Research in Vision and Ophthalmology

Disclosure: Nothing to disclose.

Ronald R Krueger, MD  Medical Director, Department of Refractive Surgery, Division of Ophthalmology, Cole Eye Institute, Cleveland Clinic Foundation

Ronald R Krueger, MD is a member of the following medical societies: American Academy of Ophthalmology, American Medical Association, American Society of Cataract and Refractive Surgery, Association for Research in Vision and Ophthalmology, International Society for Optical Engineering, and International Society of Refractive Surgery

Disclosure: Nothing to disclose.

Specialty Editor Board

Daniel S Durrie, MD  Director, Department of Ophthalmology, Division of Refractive Surgery, University of Kansas Medical Center

Daniel S Durrie, MD is a member of the following medical societies: American Academy of Ophthalmology and Association for Research in Vision and Ophthalmology

Disclosure: Nothing to disclose.

Simon K Law, MD, PharmD  Assistant Professor of Ophthalmology, Jules Stein Eye Institute; Chief of Section of Ophthalmology Surgical Services, Department of Veterans Affairs Healthcare Center, West Los Angeles

Simon K Law, MD, PharmD is a member of the following medical societies: American Academy of Ophthalmology, American Glaucoma Society, and Association for Research in Vision and Ophthalmology

Disclosure: Nothing to disclose.

Louis E Probst, MD  Medical Director of Refractive Surgery, Chicago, Madison, Milwaukee, and Windsor Centers, TLC the Laser Eye Centers

Louis E Probst, MD is a member of the following medical societies: American Academy of Ophthalmology, American Society of Cataract and Refractive Surgery, and International Society of Refractive Surgery

Disclosure: Nothing to disclose.

Lance L Brown, OD, MD  Ophthalmologist, Affiliated With Freeman Hospital and St John's Hospital, Regional Eye Center, Joplin, Missouri

Disclosure: Nothing to disclose.

Chief Editor

Hampton Roy Sr, MD  Associate Clinical Professor, Department of Ophthalmology, University of Arkansas for Medical Sciences

Hampton Roy Sr, MD is a member of the following medical societies: American Academy of Ophthalmology, American College of Surgeons, and Pan-American Association of Ophthalmology

Disclosure: Nothing to disclose.

References

  1. Scerrati E. Laser in situ keratomileusis vs. laser epithelial keratomileusis (LASIK vs. LASEK). J Refract Surg. Mar-Apr 2001;17(2 Suppl):S219-21. [Medline].

  2. Schmidt GW, Yoon M, McGwin G, Lee PP, McLeod SD. Evaluation of the relationship between ablation diameter, pupil size, and visual function with vision-specific quality-of-life measures after laser in situ keratomileusis. Arch Ophthalmol. Aug 2007;125(8):1037-42. [Medline].

  3. Camellin M, Wyler D. Epi-LASIK versus epi-LASEK. J Refract Surg. Jan 2008;24(1):S57-63. [Medline].

  4. Hammond MD, Madigan WP Jr, Bower KS. Refractive surgery in the United States Army, 2000-2003. Ophthalmology. Feb 2005;112(2):184-90. [Medline].

  5. Zhao LQ, Wei RL, Cheng JW, Li Y, Cai JP, Ma XY. Meta-analysis: clinical outcomes of laser-assisted subepithelial keratectomy and photorefractive keratectomy in myopia. Ophthalmology. Oct 2010;117(10):1912-22. [Medline].

  6. Adams GW, Hubbard AD. Kennerley Bankes Clinical Ophthalmology: A Text and Color Atlas. 4th ed. 1999.

  7. [Guideline] American Academy of Ophthalmology Refractive Management/Intervention Panel. Refractive errors & refractive surgery. San Francisco (CA): American Academy of Ophthalmology; 2007. [Full Text].

  8. Aydin B, Cagil N, Erdogan S, Erdurmus M, Hasiripi H. Effectiveness of laser-assisted subepithelial keratectomy without mitomycin-C for the treatment of high myopia. J Cataract Refract Surg. Aug 2008;34(8):1280-7. [Medline].

  9. Brown MC, Schallhorn SC, Hettinger KA, Malady SE. Satisfaction of 13,655 patients with laser vision correction at 1 month after surgery. J Refract Surg. Jul 2009;25(7 Suppl):S642-6. [Medline].

  10. Chen KH, Hsu WM, Lee SM, Lai JY, Li YS. Laser-assisted subepithelial keratectomy for dry eye associated with soft contact lenses. J Cataract Refract Surg. Dec 2005;31(12):2299-305. [Medline].

  11. Cleveland Clinic Foundation Health Information Center. LASEK: Overview. 2006;[Full Text].

  12. Gimbel HV, Penno EEA. Trends and Techniques. LASIK Complications. 3E. 184-90.

  13. Horwath-Winter J, Vidic B, Schwantzer G, Schmut O. Early changes in corneal sensation, ocular surface integrity, and tear-film function after laser-assisted subepithelial keratectomy. J Cataract Refract Surg. Nov 2004;30(11):2316-21. [Medline].

  14. Kanski, Menon, Boulton. A Systematic Approach. Clinical Ophthalmology. 5th ed. 2003:56-63.

  15. Laplace O, Bourcier T, Chaumeil C, Cardine S, Nordmann JP. Early bacterial keratitis after laser-assisted subepithelial keratectomy. J Cataract Refract Surg. Dec 2004;30(12):2638-40. [Medline].

  16. Lee HK, Lee KS, Kim JK, Kim HC, Seo KR, Kim EK. Epithelial healing and clinical outcomes in excimer laser photorefractive surgery following three epithelial removal techniques: mechanical, alcohol, and excimer laser. Am J Ophthalmol. Jan 2005;139(1):56-63. [Medline].

  17. Samalonis LB. LASEK techniques. EyeWorld. 2002;7(9):31-32.

  18. Sandoval HP, de Castro LE, Vroman DT, Solomon KD. Refractive Surgery Survey 2004. J Cataract Refract Surg. Jan 2005;31(1):221-33. [Medline].

  19. Taneri S, Zieske JD, Azar DT. Evolution, techniques, clinical outcomes, and pathophysiology of LASEK: review of the literature. Surv Ophthalmol. Nov-Dec 2004;49(6):576-602. [Medline].

  20. Vinciguerra P, Camesasca FI, Torres IM. Transition zone design and smoothing in custom laser-assisted subepithelial keratectomy. J Cataract Refract Surg. Jan 2005;31(1):39-47. [Medline].

 
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Illustration of myopia.
Illustration of hyperopia.
Illustration of an astigmatic cornea.
Illustration depicting the layers of the human cornea.
Histologic slide of the human cornea identifying its layers: (1) corneal stratified squamous epithelium with underlying Bowman layer, (2) stroma with keratocytes dispersed throughout, (3) Descemet membrane, and (4) single layer of endothelium. Image courtesy of Mission for Vision. Retrieved from http://www.missionforvisionusa.org/anatomy/2005/10/cornea.html.
Example of corneal topography. This image depicts a large inferior cone (or bulging of the cornea) along the contour of the cornea, as illustrated through the inferior red portion, which shows the steepest area of the curvature, against the blue portion, which shows the flattest portion of the curvature. Retrieved from www.opt.indiana.edu, July 22, 2006.
This image depicts the epithelial flap of a porcine eye as it is folded along its hinge to reveal the surface for laser ablation. Image courtesy of Ronald R. Krueger, MD, Cole Eye Institute, The Cleveland Clinic Foundation.
This image, taken intraoperatively on a rabbit eye, depicts the creation of the epithelial flap using the microkeratome. Image courtesy of Ronald R. Krueger, MD, Cole Eye Institute, The Cleveland Clinic Foundation.
This image depicts the epithelial flap created in laser assisted subepithelial keratectomy (LASEK) surgery on a rabbit eye. Image courtesy of Ronald R. Krueger, MD, Cole Eye Institute, The Cleveland Clinic Foundation.
Image of corneal haze following refractive surgery, as viewed through a slit lamp. Image courtesy of Ronald R. Krueger, MD, Cole Eye Institute, The Cleveland Clinic Foundation.
Relative differences of laser assisted in situ keratomileusis (LASIK), laser assisted subepithelial keratectomy (LASEK), and photorefractive keratectomy (PRK). Adapted from Taneri S, et al: Evolution, techniques, clinical outcomes, and pathophysiology of LASEK: review of the literature. Surv Ophthalmol 2004 Nov-Dec; 49(6): 576-602.
 
 
 
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