- Author: David Sarraf, MD; Chief Editor: Hampton Roy, Sr, MD more...
Lattice degeneration is a common, atrophic disease of the peripheral retina characterized by oval or linear patches of retinal thinning.[1, 2] The prevalence peaks by the second decade and is believed to be minimally progressive but may be uncommonly complicated by retinal detachment.
The pathogenesis of lattice degeneration is not well understood, although several theories have been proposed. Regional developmental absence of the internal limiting membrane versus abnormal vitreoretinal traction dynamics appears to be the most cogent argument proposed.
Lattice degeneration affects approximately 10% of the population and is bilateral in 30-50% of patients who are affected. A variable familial risk may be present on the basis of various autosomal dominant pedigrees. An increased prevalence exists in myopic eyes, and its prevalence may be associated with increasing axial length, reaching 15% in the longest eyes.
No information is available regarding the international occurrence of lattice degeneration.
See discussion of retinal detachment in History and Physical.
No reported racial differences exist in lattice degeneration.
No reported sex differences exist in lattice degeneration.
See History regarding early onset and progression with age.
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