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Exudative Retinal Detachment Follow-up

  • Author: Lihteh Wu, MD; Chief Editor: Hampton Roy, Sr, MD  more...
Updated: Mar 11, 2016

Further Inpatient Care

Most ophthalmic care is rendered in an outpatient facility. For the most part, even surgical cases are treated in an ambulatory setting.



See the list below:

  • Neovascular glaucoma
  • Phthisis bulbi


Prognosis depends on the underlying condition.

In a series of 43 patients with Coats disease, 75% of treated patients had an improvement or stabilization of vision from baseline. Only 30% of untreated patients had a stable visual acuity.[11]

The long-term prognosis in optic pits is probably poor because of secondary cystoid macular changes.[12]

Idiopathic central serous chorioretinopathy is not as benign as previously thought. As many as 15% of patients may end up with a visual acuity of 20/200 or worse.[13]

Exudative retinal detachments secondary to preeclampsia or eclampsia usually resolve without sequelae.

Contributor Information and Disclosures

Lihteh Wu, MD Asociados de Macula Vitreo y Retina de Costa Rica

Lihteh Wu, MD is a member of the following medical societies: American Academy of Ophthalmology, American Society of Retina Specialists, Association for Research in Vision and Ophthalmology, Club Jules Gonin, Macula Society, Pan-American Association of Ophthalmology, Retina Society

Disclosure: Received income in an amount equal to or greater than $250 from: Bayer Health; Quantel Medical; Heidelberg Engineering.


Dhariana Acón, MD Ophthalmologist, Caja Costarricense Seguro Social, Hospital de Guapiles, Costa Rica

Disclosure: Nothing to disclose.

Specialty Editor Board

Simon K Law, MD, PharmD Clinical Professor of Health Sciences, Department of Ophthalmology, Jules Stein Eye Institute, University of California, Los Angeles, David Geffen School of Medicine

Simon K Law, MD, PharmD is a member of the following medical societies: American Academy of Ophthalmology, Association for Research in Vision and Ophthalmology, American Glaucoma Society

Disclosure: Nothing to disclose.

Steve Charles, MD Director of Charles Retina Institute; Clinical Professor, Department of Ophthalmology, University of Tennessee College of Medicine

Steve Charles, MD is a member of the following medical societies: American Academy of Ophthalmology, American Society of Retina Specialists, Macula Society, Retina Society, Club Jules Gonin

Disclosure: Received royalty and consulting fees for: Alcon Laboratories.

Chief Editor

Hampton Roy, Sr, MD Associate Clinical Professor, Department of Ophthalmology, University of Arkansas for Medical Sciences

Hampton Roy, Sr, MD is a member of the following medical societies: American Academy of Ophthalmology, American College of Surgeons, Pan-American Association of Ophthalmology

Disclosure: Nothing to disclose.

Additional Contributors

V Al Pakalnis, MD, PhD Professor of Ophthalmology, University of South Carolina School of Medicine; Chief of Ophthalmology, Dorn Veterans Affairs Medical Center

V Al Pakalnis, MD, PhD is a member of the following medical societies: American Academy of Ophthalmology, American College of Surgeons, South Carolina Medical Association

Disclosure: Nothing to disclose.


Teodoro Evans, MD Consulting Surgeon, Vitreo-Retinal Section, Clinica de Ojos, Costa Rica

Disclosure: Nothing to disclose.

  1. Kase S, Rao NA, Yoshikawa H, Fukuhara J, Noda K, Kanda A. Expression of vascular endothelial growth factor in eyes with Coats' disease. Invest Ophthalmol Vis Sci. 2013 Jan. 54(1):57-62. [Medline].

  2. Kim RY, Loewenstein JI. Systemic diseases manifesting as exudative retinal detachment. Int Ophthalmol Clin. 1998 Winter. 38(1):177-95. [Medline].

  3. Suzani M, Moore AT. Intraoperative fluorescein angiography-guided treatment in children with early Coats' disease. Ophthalmology. 2015 Jun. 122 (6):1195-202. [Medline].

  4. Rao NA. Pathology of Vogt-Koyanagi-Harada disease. Int Ophthalmol. 2007 Apr-Jun. 27(2-3):81-5. [Medline].

  5. Andreoli CM, Foster CS. Vogt-Koyanagi-Harada disease. Int Ophthalmol Clin. 2006 Spring. 46(2):111-22. [Medline].

  6. Yasuzumi K, Futagami S, Kiyosawa M, Mochizuki M. Bilateral serous retinal detachment associated with Alport's syndrome. Ophthalmologica. 2000. 214(4):301-4. [Medline].

  7. Zhao Q, Peng XY, Chen FH, Zhang YP, Wang L, You QS. Vascular endothelial growth factor in Coats' disease. Acta Ophthalmol. 2013 Jun 13. [Medline].

  8. Sigler EJ, Randolph JC, Calzada JI, Wilson MW, Haik BG. Current management of Coats disease. Surv Ophthalmol. 2014 Jan-Feb. 59(1):30-46. [Medline].


  10. Salehi M, Wenick AS, Law HA, Evans JR, Gehlbach P. Interventions for central serous chorioretinopathy: a network meta-analysis. Cochrane Database Syst Rev. 2015 Dec 22. 12:CD011841. [Medline].

  11. Shields JA, Shields CL. Review: coats disease: the 2001 LuEsther T. Mertz lecture. Retina. 2002 Feb. 22(1):80-91. [Medline].

  12. McDonald HR, Schatz H, Johnson RN. Treatment of retinal detachment associated with optic pits. Int Ophthalmol Clin. 1992 Spring. 32(2):35-42. [Medline].

  13. Wang M, Munch IC, Hasler PW, Prunte C, Larsen M. Central serous chorioretinopathy. Acta Ophthalmol. 2008 Mar. 86(2):126-45. [Medline].

  14. Aaberg TM, Pawlowski GJ. Exudative retinal detachments following scleral buckling with cryotherapy. Am J Ophthalmol. 1972 Aug. 74(2):245-51. [Medline].

  15. Blair CJ, Aaberg TM. Massive subretinal exudation associated with senile macular degeneration. Am J Ophthalmol. 1971 Mar. 71(3):639-48. [Medline].

  16. Brockhurst RJ. Nanophthalmos with uveal effusion. A new clinical entity. Arch Ophthalmol. 1975 Dec. 93(12):1989-99. [Medline].

  17. Brockhurst RJ. Vortex vein decompression for nanophthalmic uveal effusion. Arch Ophthalmol. 1980 Nov. 98(11):1987-90. [Medline].

  18. Brown GC, Shields JA, Goldberg RE. Congenital pits of the optic nerve head. II. Clinical studies in humans. Ophthalmology. 1980 Jan. 87(1):51-65. [Medline].

  19. Cameron JR, Cackett P. Lymphomatoid granulomatosis associated with bilateral exudative retinal detachments. Arch Ophthalmol. 2007 May. 125(5):712-3. [Medline].

  20. Chan DP, Teoh SC, Tan CS, et al. Ophthalmic complications of dengue. Emerg Infect Dis. 2006 Feb. 12(2):285-9. [Medline].

  21. Chang S, Haik BG, Ellsworth RM, St Louis L, Berrocal JA. Treatment of total retinal detachment in morning glory syndrome. Am J Ophthalmol. 1984 May. 97(5):596-600. [Medline].

  22. DeLuise VP, Clark SW 3rd, Smith JL. Syphilitic retinal detachment and uveal effusion. Am J Ophthalmol. 1982 Dec. 94(6):757-61. [Medline].

  23. Dey M, Situnayake D, Sgouros S, Stavrou P. Bilateral exudative retinal detachment in a child with orbital pseudotumor. J Pediatr Ophthalmol Strabismus. 2007 May-Jun. 44(3):183-6. [Medline].

  24. Durant WJ, Jampol LM, Daily M. Exudative retinal detachment in hemoglobin SC disease. Retina. 1982. 2(3):152-4. [Medline].

  25. Gass JD. Bullous retinal detachment. An unusual manifestation of idiopathic central serous choroidopathy. Am J Ophthalmol. 1973 May. 75(5):810-21. [Medline].

  26. Gass JD. Uveal effusion syndrome: a new hypothesis concerning pathogenesis and technique of surgical treatment. Trans Am Ophthalmol Soc. 1983. 81:246-60. [Medline].

  27. Hsu J, Forbes B, Maguire AM. Total exudative retinal detachment in coats disease: biochemical analysis of the subretinal exudate. Retina. 2006 Sep. 26(7):831-3. [Medline].

  28. Hunyor AP, Harper CA, O'Day J, McKelvie PA. Ocular-central nervous system lymphoma mimicking posterior scleritis with exudative retinal detachment. Ophthalmology. 2000 Oct. 107(10):1955-9. [Medline].

  29. Jaben SL, Norton EW. Exudative retinal detachment in Wegener's granulomatosis: case report. Ann Ophthalmol. 1982 Aug. 14(8):717-20. [Medline].

  30. Jumper JM, Machemer R, Gallemore RP, Jaffe GJ. Exudative retinal detachment and retinitis associated with acquired syphilitic uveitis. Retina. 2000. 20(2):190-4. [Medline].

  31. Kielar RA. Exudative retinal detachment and scleritis in polyarteritis. Am J Ophthalmol. 1976 Nov. 82(5):694-8. [Medline].

  32. Marmor MF. New hypotheses on the pathogenesis and treatment of serous retinal detachment. Graefes Arch Clin Exp Ophthalmol. 1988. 226(6):548-52. [Medline].

  33. Negi A, Marmor MF. Experimental serous retinal detachment and focal pigment epithelial damage. Arch Ophthalmol. 1984 Mar. 102(3):445-9. [Medline].

  34. Negi A, Marmor MF. The resorption of subretinal fluid after diffuse damage to the retinal pigment epithelium. Invest Ophthalmol Vis Sci. 1983 Nov. 24(11):1475-9. [Medline].

  35. Oliver M, Uchenik D. Bilateral exudative retinal detachment in eclampsia without hypertensive retinopathy. Am J Ophthalmol. 1980 Dec. 90(6):792-6. [Medline].

  36. Ridley ME, Shields JA, Brown GC, Tasman W. Coats' disease. Evaluation of management. Ophthalmology. 1982 Dec. 89(12):1381-7. [Medline].

  37. Schepens CL, Brockhurst RJ. Uveal effusion: 1. Clinical picture. Arch Ophthalmol. 1963. 70:189-201.

  38. Spaide RF, Goldbaum M, Wong DW, Tang KC, Iida T. Serous detachment of the retina. Retina. 2003 Dec. 23(6):820-46; quiz 895-6. [Medline].

  39. Stropes LL, Luft FC. Hypertensive crisis with bilateral bullous retinal detachment. JAMA. 1977 Oct 31. 238(18):1948-9. [Medline].

  40. Tasman W. Exudative retinal detachment in retrolental fibroplasia. Trans Sect Ophthalmol Am Acad Ophthalmol Otolaryngol. 1977 May-Jun. 83(3 Pt 1):535-40. [Medline].

  41. Topilow HW, Ackerman AL. Massive exudative retinal and choroidal detachments following scleral buckling surgery. Ophthalmology. 1983 Feb. 90(2):143-7. [Medline].

  42. Tseng SH. Surgical debridement of scleral abscesses with concomitant resolution of the complicating exudative retinal detachment. Ophthalmic Surg Lasers. 1998 Nov. 29(11):939-42. [Medline].

  43. Tsukahara I, Uyama M. Central serous choroidopathy with bullous retinal detachment. Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1978 May 16. 206(3):169-78. [Medline].

  44. Weiter JJ, Brockhurst RJ, Tolentino FI. Uveal effusion following pan-retinal photocoagulation. Ann Ophthalmol. 1979 Nov. 11(11):1723-7. [Medline].

  45. Yao XY, Marmor MF. Induction of serous retinal detachment in rabbit eyes by pigment epithelial and choriocapillary injury. Arch Ophthalmol. 1992 Apr. 110(4):541-6. [Medline].

  46. Yuen KS, Lai CH, Chan WM, Lam DS. Bilateral exudative retinal detachments as the presenting features of idiopathic orbital inflammation. Clin Experiment Ophthalmol. 2005 Dec. 33(6):671-4. [Medline].

An 8-year-old boy with Coats disease. Notice the macular exudation.
An 8-year-old boy with Coats disease. Notice the peripheral vascular dilatations. This patient underwent cryotherapy months before, and the exudative retinal detachment has basically disappeared.
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