eMedicine Specialties > Ophthalmology > Retina

Retinal Detachment, Rhegmatogenous: Differential Diagnoses & Workup

Author: Lihteh Wu, MD, Consulting Surgeon, Department of Ophthalmology, Vitreo-Retinal Section, Instituto De Cirugia Ocular, Costa Rica
Coauthor(s): Teodoro Evans, MD, Retina Fellow, Vitreo-Retinal Section, Instituto De Cirugia Ocular, Costa Rica
Contributor Information and Disclosures

Updated: Aug 2, 2007

Differential Diagnoses

Acute Retinal Necrosis
Retinitis, CMV
Retinal Detachment, Exudative
Retinoschisis, Senile
Retinal Detachment, Postoperative
Retinal Detachment, Proliferative
Retinal Detachment, Tractional

Workup

Imaging Studies

  • Ultrasound
    • On certain occasions, the media may not be clear, impairing a thorough retinal examination with the binocular indirect ophthalmoscope. An ultrasound is a useful adjunct in these situations.
    • Ultra–high-frequency sounds travel to the back of the eye as the probe emits them. Once a structure is contacted by the sound waves, the sound wave is attenuated and reflected back to the probe. The pattern of these waves is specific for certain tissues. Thus, localization and tissue characterization is possible using this technique. Typically, an A scan and a B scan are obtained. For instance, retinal tissue usually shows a large spike in the A scan, reflecting an increased acoustic density of the tissue. The B scan shows a composite picture of the globe and its intraocular contents.
    • Sometimes, it may be difficult to differentiate a retinal detachment from a thickened, partially detached posterior hyaloid. In this case, A-scan and B-scan findings often overlap. Tissue mobility during scanning may help to differentiate the two. Usually, a RRD has a characteristic undulating motion after a sudden saccade, whereas a thickened posterior hyaloid moves in a brisker manner but with less excursion.
  • Fluorescein angiography (FA): Cystoid macular edema may complicate the postoperative course of an eye that has undergone retinal reattachment surgery. FA is a useful adjunct in helping to diagnose this condition.
  • Optical coherence tomography (OCT): Occasionally, certain eyes appear to have complete retinal reattachment, but the visual acuity appears to be incomplete or delayed. OCT helps to reveal subfoveal fluid in these eyes.

Other Tests

  • Electroretinogram (ERG): When a patient presents with a dense vitreous hemorrhage or a cataract that precludes direct visualization of the retina, an ultrasound of the posterior pole is indicated. Sometimes, differentiating a RRD and a thickened posterior hyaloid that is partially detached using ultrasound is difficult. In these circumstances, an ERG is a useful adjunct in the evaluation of a patient suspected of having a RRD. If a good response from the ERG is obtained, the retina is probably attached. If the electric response from the retina is attenuated to a great degree, the retina is probably detached.

Histologic Findings

During separation of the neurosensory retina from the RPE, the choroidal blood flow to the outer retinal layers is lost. The RPE also loses its ability to modulate the health of the outer segments of the photoreceptors. Initially, the outer segments of the photoreceptors are lost. After successful retinal reattachment, the outer segments may regenerate. As the detachment becomes more chronic, atrophy of the entire photoreceptor layer, cystic degeneration, macrocyst formation, demarcation lines, and even rubeosis iridis may be seen.

More on Retinal Detachment, Rhegmatogenous

Overview: Retinal Detachment, Rhegmatogenous
Differential Diagnoses & Workup: Retinal Detachment, Rhegmatogenous
Treatment & Medication: Retinal Detachment, Rhegmatogenous
Follow-up: Retinal Detachment, Rhegmatogenous
Multimedia: Retinal Detachment, Rhegmatogenous
References

References

  1. Haimann MH, Burton TC, Brown CK. Epidemiology of retinal detachment. Arch Ophthalmol. Feb 1982;100(2):289-92. [Medline].

  2. Wilkes SR, Beard CM, Kurland LT, Robertson DM, O'Fallon WM. The incidence of retinal detachment in Rochester, Minnesota, 1970-1978. Am J Ophthalmol. Nov 1982;94(5):670-3. [Medline].

  3. Laatikainen L, Tolppanen EM, Harju H. Epidemiology of rhegmatogenous retinal detachment in a Finnish population. Acta Ophthalmol (Copenh). Feb 1985;63(1):59-64. [Medline].

  4. Tornquist R, Stenkula S, Tornquist P. Retinal detachment. A study of a population-based patient material in Sweden 1971-1981. I. Epidemiology. Acta Ophthalmol (Copenh). Apr 1987;65(2):213-22. [Medline].

  5. Sasaki K, Ideta H, Yonemoto J, Tanaka S, Hirose A, Oka C. Epidemiologic characteristics of rhegmatogenous retinal detachment in Kumamoto, Japan. Graefes Arch Clin Exp Ophthalmol. Dec 1995;233(12):772-6. [Medline].

  6. Wong TY, Tielsch JM, Schein OD. Racial difference in the incidence of retinal detachment in Singapore. Arch Ophthalmol. Mar 1999;117(3):379-83. [Medline].

  7. Custodis E. Beobachtungen bei der diathermischen Behandlung der Netzhautablosung und ein Minweis zur Therapie der Amotio retinae. Ber Dtsch Ophthalmol Ges. 1952;57:227.

  8. Lincoff HA, Baras I, McLean JM. Modification to the Custodis procedure for retinal detachment. Arch Ophthalmol. 1965;73:160-3.

  9. Schepens CL, Okamura ID, Brockhurst RJ. The scleral buckling procedures. I. Surgical techniques and management. Arch Ophthalmol. 1957;58:797.

  10. Chignell AH. Retinal detachment surgery without drainage of subretinal fluid. Am J Ophthalmol. Jan 1974;77(1):1-5. [Medline].

  11. Lincoff H, Kreissig I. The treatment of retinal detachment without drainage of subretinal fluid. (Modifications of the Custodis procedure. VI). Trans Am Acad Ophthalmol Otolaryngol. Sep-Oct 1972;76(5):1121-33. [Medline].

  12. Escoffery RF, Olk RJ, Grand MG, Boniuk I. Vitrectomy without scleral buckling for primary rhegmatogenous retinal detachment. Am J Ophthalmol. Mar 15 1985;99(3):275-81. [Medline].

  13. Gartry DS, Chignell AH, Franks WA, Wong D. Pars plana vitrectomy for the treatment of rhegmatogenous retinal detachment uncomplicated by advanced proliferative vitreoretinopathy. Br J Ophthalmol. Apr 1993;77(4):199-203. [Medline].

  14. Hakin KN, Lavin MJ, Leaver PK. Primary vitrectomy for rhegmatogenous retinal detachment. Graefes Arch Clin Exp Ophthalmol. Jun 1993;231(6):344-6. [Medline].

  15. Oshima Y, Yamanishi S, Sawa M, Motokura M, Harino S, Emi K. Two-year follow-up study comparing primary vitrectomy with scleral buckling for macula-off rhegmatogenous retinal detachment. Jpn J Ophthalmol. Sep-Oct 2000;44(5):538-49. [Medline].

  16. Hilton GF, Tornambe PE. Pneumatic retinopexy. An analysis of intraoperative and postoperative complications. The Retinal Detachment Study Group. Retina. 1991;11(3):285-94. [Medline].

  17. McAllister IL, Meyers SM, Zegarra H, Gutman FA, Zakov ZN, Beck GJ. Comparison of pneumatic retinopexy with alternative surgical techniques. Ophthalmology. Jul 1988;95(7):877-83. [Medline].

  18. Tornambe PE, Hilton GF. Pneumatic retinopexy. A multicenter randomized controlled clinical trial comparing pneumatic retinopexy with scleral buckling. The Retinal Detachment Study Group. Ophthalmology. Jun 1989;96(6):772-83; discussion 784. [Medline].

  19. Tornambe PE, Hilton GF, Brinton DA, Flood TP, Green S, Grizzard WS, et al. Pneumatic retinopexy. A two-year follow-up study of the multicenter clinical trial comparing pneumatic retinopexy with scleral buckling. Ophthalmology. Jul 1991;98(7):1115-23. [Medline].

  20. Lincoff HA, Kreissig I, Hahn YS. A temporary balloon buckle for the treatment of small retinal detachments. Ophthalmology. Apr 1979;86(4):586-96. [Medline].

  21. Wilkinson C. Interventions for asymptomatic retinal breaks and lattice degeneration for preventing retinal detachment. Cochrane Database Syst Rev. 2005;(1):CD003170. [Medline].

  22. Amato JE, Akduman L. Incidence of complications in 25-gauge transconjunctival sutureless vitrectomy based on the surgical indications. Ophthalmic Surg Lasers Imaging. Mar-Apr 2007;38(2):100-2. [Medline].

  23. Ambler JS, Meyers SM, Zegarra H, Paranandi L. Reoperations and visual results after failed pneumatic retinopexy. Ophthalmology. Jun 1990;97(6):786-90. [Medline].

  24. Azad RV, Chanana B, Sharma YR, Vohra R. Primary vitrectomy versus conventional retinal detachment surgery in phakic rhegmatogenous retinal detachment. Acta Ophthalmol Scand. Aug 2007;85(5):540-5. [Medline].

  25. Burton TC. Preoperative factors influencing anatomic success rates following retinal detachment surgery. Trans Sect Ophthalmol Am Acad Ophthalmol Otolaryngol. May-Jun 1977;83(3 Pt 1):OP499-505. [Medline].

  26. Burton TC, Lambert RW Jr. A predictive model for visual recovery following retinal detachment surgery. Ophthalmology. Jun 1978;85(6):619-25. [Medline].

  27. Byer NE. Cystic retinal tufts and their relationship to retinal detachment. Arch Ophthalmol. Oct 1981;99(10):1788-90. [Medline].

  28. Byer NE. Long-term natural history of lattice degeneration of the retina. Ophthalmology. Sep 1989;96(9):1396-401; discussion 1401-2. [Medline].

  29. Byer NE. Long-term natural history study of senile retinoschisis with implications for management. Ophthalmology. Sep 1986;93(9):1127-37. [Medline].

  30. Byer NE. Natural history of posterior vitreous detachment with early management as the premier line of defense against retinal detachment. Ophthalmology. Sep 1994;101(9):1503-13; discussion 1513-4. [Medline].

  31. Byer NE. The natural history of asymptomatic retinal breaks. Ophthalmology. Sep 1982;89(9):1033-9. [Medline].

  32. Byer NE. What happens to untreated asymptomatic retinal breaks, and are they affected by posterior vitreous detachment?. Ophthalmology. Jun 1998;105(6):1045-9; discussion 1049-50. [Medline].

  33. Campochiaro PA, Kaden IH, Vidaurri-Leal J, Glaser BM. Cryotherapy enhances intravitreal dispersion of viable retinal pigment epithelial cells. Arch Ophthalmol. Mar 1985;103(3):434-6. [Medline].

  34. Chan CK, Wessels IF. Delayed subretinal fluid absorption after pneumatic retinopexy. Ophthalmology. Dec 1989;96(12):1691-700. [Medline].

  35. Chen E. 25-Gauge transconjunctival sutureless vitrectomy. Curr Opin Ophthalmol. May 2007;18(3):188-93. [Medline].

  36. Chen SN, Hwang JF. Treatment of rhegmatogenous retinal detachment in teenagers by pneumatic retinopexy technique. Am J Ophthalmol. Feb 2007;143(2):217-221. [Medline].

  37. Chignell AH, Talbot J. Absorption of subretinal fluid after nondrainage retinal detachment surgery. Arch Ophthalmol. Apr 1978;96(4):635-7. [Medline].

  38. Christensen U, Sander B, Villumsen J. Retinal thickening after successful surgery for macula-off retinal detachment. Curr Eye Res. Jan 2007;32(1):65-9. [Medline].

  39. Clarkson JG, Blumenkranz MS, Culbertson WW, Flynn HW Jr, Lewis ML. Retinal detachment following the acute retinal necrosis syndrome. Ophthalmology. Dec 1984;91(12):1665-8. [Medline].

  40. Dieckert JP, O'Connor PS, Schacklett DE, Tredici TJ, Lambert HM, Fanton JW, et al. Air travel and intraocular gas. Ophthalmology. May 1986;93(5):642-5. [Medline].

  41. Diederen RM, La Heij EC, Kessels AG, Goezinne F, Liem AT, Hendrikse F. Scleral buckling surgery after macula-off retinal detachment: worse visual outcome after more than 6 days. Ophthalmology. Apr 2007;114(4):705-9. [Medline].

  42. Dominguez DA. Cirugia precoz y ambulatoria del desprendimiento de retina. Arch Soc Esp Oftalmol. 1985;48:47.

  43. Eckardt C. Transconjunctival sutureless 23-gauge vitrectomy. Retina. Feb-Mar 2005;25(2):208-11. [Medline].

  44. Fine HF, Iranmanesh R, Iturralde D, Spaide RF. Outcomes of 77 consecutive cases of 23-gauge transconjunctival vitrectomy surgery for posterior segment disease. Ophthalmology. Jun 2007;114(6):1197-200. [Medline].

  45. Foos RY. Posterior vitreous detachment. Trans Am Acad Ophthalmol Otolaryngol. Mar-Apr 1972;76(2):480-97. [Medline].

  46. Foos RY, Wheeler NC. Vitreoretinal juncture. Synchysis senilis and posterior vitreous detachment. Ophthalmology. Dec 1982;89(12):1502-12. [Medline].

  47. Freeman WR, Henderly DE, Wan WL, Causey D, Trousdale M, Green RL, et al. Prevalence, pathophysiology, and treatment of rhegmatogenous retinal detachment in treated cytomegalovirus retinitis. Am J Ophthalmol. Apr 15 1987;103(4):527-36. [Medline].

  48. Goldmann H. Zur Biomikroskopie des Glaskorpers. Ophthalmologica. 1954;127:334.

  49. Hilton GF, Grizzard WS. Pneumatic retinopexy. A two-step outpatient operation without conjunctival incision. Ophthalmology. May 1986;93(5):626-41. [Medline].

  50. Holland GN. Standard diagnostic criteria for the acute retinal necrosis syndrome. Executive Committee of the American Uveitis Society. Am J Ophthalmol. May 15 1994;117(5):663-7. [Medline].

  51. Holland SP, Pulido JS, Miller D, Ellis B, Alfonso E, Scott M, et al. Biofilm and scleral buckle-associated infections. A mechanism for persistence. Ophthalmology. Jun 1991;98(6):933-8. [Medline].

  52. Kanski JJ, Elkington AR, Davies MS. Diplopia after retinal detachment surgery. Am J Ophthalmol. Jul 1973;76(1):38-40. [Medline].

  53. Kawahara S, Nagai Y, Kawakami E. Ciliochoroidal Detachment Following Scleral Buckling Surgery for Rhegmatogenous Retinal Detachment. Jpn J Ophthalmol. Nov 1 2000;44(6):692-693. [Medline].

  54. Kon CH, Asaria RH, Occleston NL, Khaw PT, Aylward GW. Risk factors for proliferative vitreoretinopathy after primary vitrectomy: a prospective study. Br J Ophthalmol. May 2000;84(5):506-11. [Medline].

  55. La Heij EC, Derhaag PF, Hendrikse F. Results of scleral buckling operations in primary rhegmatogenous retinal detachment. Doc Ophthalmol. 2000;100(1):17-25. [Medline].

  56. Li X. Incidence and epidemiological characteristics of rhegmatogenous retinal detachment in Beijing, China. Ophthalmology. Dec 2003;110(12):2413-7. [Medline].

  57. Lincoff H, McLean JM, Nano H. Cryosurgical treatment of retinal detachment. Trans Am Acad Ophthalmol Otolaryngol. 1964;68:412-32.

  58. Lobes LA Jr, Grand MG. Incidence of cystoid macular edema following scleral buckling procedure. Arch Ophthalmol. Jul 1980;98(7):1230-2. [Medline].

  59. Lobes LA, Burton TC. The incidence of macular pucker after retinal detachment surgery. Am J Ophthalmol. Jan 1978;85(1):72-7. [Medline].

  60. Mastropasqua L, Carpineto P, Ciancaglini M, Falconio G, Gallenga PE. Treatment of retinal tears and lattice degenerations in fellow eyes in high risk patients suffering retinal detachment: a prospective study. Br J Ophthalmol. Sep 1999;83(9):1046-9. [Medline].

  61. McDonald HR, Abrams GW, Irvine AR, Sipperley JO, Boyden BS, Fiore JV Jr, et al. The management of subretinal gas following attempted pneumatic retinal reattachment. Ophthalmology. Apr 1987;94(4):319-26. [Medline].

  62. Meredith TA, Reeser FH, Topping TM, Aaberg TM. Cystoid macular edema after retinal detachment surgery. Ophthalmology. Nov 1980;87(11):1090-5. [Medline].

  63. Oshima Y, Emi K, Motokura M, Yamanishi S. Survey of surgical indications and results of primary pars plana vitrectomy for rhegmatogenous retinal detachments. Jpn J Ophthalmol. Mar-Apr 1999;43(2):120-6. [Medline].

  64. Packer AJ, Maggiano JM, Aaberg TM, Meredith TA, Reeser FH, Kingham JD. Serous choroidal detachment after retinal detachment surgery. Arch Ophthalmol. Aug 1983;101(8):1221-4. [Medline].

  65. Perez RN, Phelps CD, Burton TC. Angel-closure glaucoma following scleral buckling operations. Trans Am Acad Ophthalmol Otolaryngol. Mar-Apr 1976;81(2):247-52. [Medline].

  66. Richardson EC, Verma S, Green WT, Woon H, Chignell AH. Primary vitrectomy for rhegmatogenous retinal detachment: an analysis of failure. Eur J Ophthalmol. Apr-Jun 2000;10(2):160-6. [Medline].

  67. Rizzo S, Genovesi-Ebert F, Murri S, Belting C, Vento A, Cresti F, et al. 25-gauge, sutureless vitrectomy and standard 20-gauge pars plana vitrectomy in idiopathic epiretinal membrane surgery: a comparative pilot study. Graefes Arch Clin Exp Ophthalmol. Apr 2006;244(4):472-9. [Medline].

  68. Ross WH, Stockl FA. Visual recovery after retinal detachment. Curr Opin Ophthalmol. Jun 2000;11(3):191-4. [Medline].

  69. Ryan SJ, Goldberg MF. Anterior segment ischemia following scleral buckling in sickle cell hemoglobinopathy. Am J Ophthalmol. Jul 30 1971;72(1):35-50. [Medline].

  70. Saw SM, Gazzard G, Wagle AM, Lim J, Au Eong KG. An evidence-based analysis of surgical interventions for uncomplicated rhegmatogenous retinal detachment. Acta Ophthalmol Scand. Oct 2006;84(5):606-12. [Medline].

  71. Schepens CL, Marden D. Data on the natural history of retinal detachment. I. Age and sex relationships. Arch Ophthalmol. 1961;66:631.

  72. Schwartz SG, Flynn HW. Primary retinal detachment: scleral buckle or pars plana vitrectomy?. Curr Opin Ophthalmol. Jun 2006;17(3):245-50. [Medline].

  73. Smiddy WE, Loupe D, Michels RG, Enger C, Glaser BM, deBustros S. Extraocular muscle imbalance after scleral buckling surgery. Ophthalmology. Oct 1989;96(10):1485-9; discussion 1489-90. [Medline].

  74. Smiddy WE, Loupe DN, Michels RG, Enger C, Glaser BM, deBustros S. Refractive changes after scleral buckling surgery. Arch Ophthalmol. Oct 1989;107(10):1469-71. [Medline].

  75. Spencer LM, Foos RY, Straatsma BR. Enclosed bays of the ora serrata. Relationship to retina tears. Arch Ophthalmol. Apr 1970;83(4):421-5. [Medline].

  76. Tanner V, Harle D, Tan J, Foote B, Williamson TH, Chignell AH. Acute posterior vitreous detachment: the predictive value of vitreous pigment and symptomatology. Br J Ophthalmol. Nov 2000;84(11):1264-8. [Medline].

  77. Tillery WV, Lucier AC. Round atrophic holes in lattice degeneration--an important cause of phakic retinal detachment. Trans Sect Ophthalmol Am Acad Ophthalmol Otolaryngol. May-Jun 1976;81(3 Pt 1):509-18. [Medline].

  78. Wilkinson CP. Evidence-based medicine regarding the prevention of retinal detachment. Trans Am Ophthalmol Soc. 1999;97:397-404; discussion 404-6. [Medline].

  79. Wilkinson CP, Bradford RH. Complications of draining subretinal fluid. Retina. Winter-Spring 1984;4(1):1-4. [Medline].

  80. Wolfensberger TJ. Foveal reattachment after macula-off retinal detachment occurs faster after vitrectomy than after buckle surgery. Ophthalmology. Jul 2004;111(7):1340-3. [Medline].

  81. Wolfensberger TJ, Gonvers M. Optical coherence tomography in the evaluation of incomplete visual acuity recovery after macula-off retinal detachments. Graefes Arch Clin Exp Ophthalmol. Feb 2002;240(2):85-9. [Medline].

  82. Wright LA, Cleary M, Barrie T, Hammer HM. Motility and binocularity outcomes in vitrectomy versus scleral buckling in retinal detachment surgery. Graefes Arch Clin Exp Ophthalmol. Dec 1999;237(12):1028-32. [Medline].

  83. Yeo JH, Vidaurri-Leal J, Glaser BM. Extension of retinal detachments as a complication of pneumatic retinopexy. Arch Ophthalmol. Aug 1986;104(8):1161-3. [Medline].

Further Reading

Keywords

rhegmatogenous retinal detachment, RRD, subretinal fluid accumulation, retinal tear, neurosensory retina, retinal pigment epithelium, RPE, vitreoretinal traction, posterior vitreous detachment, PVD, vitreoretinal adhesions

Contributor Information and Disclosures

Author

Lihteh Wu, MD, Consulting Surgeon, Department of Ophthalmology, Vitreo-Retinal Section, Instituto De Cirugia Ocular, Costa Rica
Lihteh Wu, MD is a member of the following medical societies: American Academy of Ophthalmology, American Society of Retina Specialists, Association for Research in Vision and Ophthalmology, and Pan-American Association of Ophthalmology
Disclosure: Nothing to disclose.

Coauthor(s)

Teodoro Evans, MD, Retina Fellow, Vitreo-Retinal Section, Instituto De Cirugia Ocular, Costa Rica
Disclosure: Nothing to disclose.

Medical Editor

Vytautas A Pakainis, MD, Chief of Ophthalmology, Dorn Veterans Administration Medical Center, Professor of Ophthalmology, Ophthalmology, University of South Carolina School of Medicine
Vytautas A Pakainis, MD is a member of the following medical societies: American Academy of Ophthalmology, American College of Surgeons, and South Carolina Medical Association
Disclosure: Nothing to disclose.

Pharmacy Editor

Simon K Law, MD, PharmD, Assistant Professor of Ophthalmology, Jules Stein Eye Institute; Chief of Section of Ophthalmology Surgical Services, Department of Veterans Affairs Healthcare Center, West Los Angeles
Simon K Law, MD, PharmD is a member of the following medical societies: American Academy of Ophthalmology, American Glaucoma Society, and Association for Research in Vision and Ophthalmology
Disclosure: Nothing to disclose.

Managing Editor

Steve Charles, MD, Director of Charles Retina Institute; Clinical Professor, Department of Ophthalmology, University of Tennessee College of Medicine
Steve Charles, MD is a member of the following medical societies: American Academy of Ophthalmology, American Society of Retina Specialists, Club Jules Gonin, Macula Society, and Retina Society
Disclosure: Alcon Laboratories Consulting fee Consulting; OptiMedica Ownership interest Consulting

CME Editor

Lance L Brown, OD, MD, Ophthalmologist, Affiliated With Freeman Hospital and St John's Hospital, Regional Eye Center, Joplin, Missouri
Disclosure: Nothing to disclose.

Chief Editor

Hampton Roy Sr, MD, Associate Clinical Professor, Department of Ophthalmology, University of Arkansas for Medical Sciences
Hampton Roy Sr, MD is a member of the following medical societies: American Academy of Ophthalmology, American College of Surgeons, and Pan-American Association of Ophthalmology
Disclosure: Nothing to disclose.

 
 
HONcode

We subscribe to the
HONcode principles of the
Health On the Net Foundation

All material on this website is protected by copyright, Copyright© 1994- by Medscape.
This website also contains material copyrighted by 3rd parties.

DISCLAIMER: The content of this Website is not influenced by sponsors. The site is designed primarily for use by qualified physicians and other medical professionals. The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for educational and informational purposes only. In no way should it be considered as offering medical advice. Please check with a physician if you suspect you are ill.